Protein Alignment Nepl14 and Nepl4

DIOPT Version :10

• Sequence 1: NP_651097.1
• Gene: Nepl14 / 42700
• FlyBaseID: FBgn0039023
• Length: 696
• Species: Drosophila melanogaster
• Sequence 2: NP_609019.1
• Gene: Nepl4 / 33889
• FlyBaseID: FBgn0031805
• Length: 652
• Species: Drosophila melanogaster
• Alignment Length: 758
• Identity: 151/758 - (19%)
• Similarity: 274/758 - (36%)
• Gaps: 191/758 - (25%)

  Fly    14 LWLPHLQQNALVSGEDLP----PPFQR---IYQSEQTVRRSKAQDMGSHVNKSIDPCVDFYAYAC 71
            ||...|...:...|..:|    .|.|.   :.:...|:.:.....:.|:|:...:||.|||||||
  Fly     5 LWTALLLLGSATCGSSVPVKANDPEQSCPYLGECNSTINQQHIDTLMSYVDSEKNPCEDFYAYAC 69

  Fly    72 GNWK--------STLTPQQQLQQQTDRELLLLVEEAVRREDSVIVRQAKEL--FKSCVSAQAHQS 126
            |.|:        :|:..:.|:.:|.:...|.|:......|....: .||.|  ::||::.:....
  Fly    70 GKWRAKHGSHTTATMISESQINRQYEDLFLQLLRNPSAPEYGYPM-FAKVLAHYQSCIALEKPDL 133

  Fly   127 QQQQHFLSEFINQNGGFPAVPGSQWAVHHHDYNWLSVLGGLRLRYGMDILIG--LRVGYNYGNVN 189
            ::....|...:     ..::..:.|      .:.|:.||    |||..   |  ::|...:.|..
  Fly   134 RRYIELLDRDL-----LASLNSTHW------MHLLAALG----RYGYH---GHYVQVEVRWYNAT 180

  Fly   190 ENSLYLSEPSTLIPTELCTRNRS---DIRDSIYEPLEHRVASELKSWLALGHDESARLAADILSF 251
            .:.::      |:|     .||.   .:...||:.|    :.:..||..| |    :|.....|.
  Fly   181 HHMIF------LLP-----HNRHLNLSLTQDIYDAL----SQDGSSWPPL-H----QLQEQFRSL 225

  Fly   252 EHELCGGMKGGSFESWDAEEQLYLANYTRKTLREFSNSIELDLDSYVRASFGQD-----IYKPVY 311
            |..|....|..|.:.       ...||:...:|  :....|..|..:|...|:.     :::...
  Fly   226 EQNLVRLAKPHSADD-------TFRNYSLDQIR--TEVPGLHWDEALRTQLGRSVPGNHVFQVDD 281

  Fly   312 MAAPEYFRQLKRTVSAHNISLVANYIMYRAVSAL----NFPL---DDRPQLRKRECLERTKELLP 369
            :.|.|...:...||   :..|:..|.:.|.:|.|    :.||   :...:.|.|.|:...:..:.
  Fly   282 LDAIEGLVEYLNTV---DTLLLNRYSLARFLSHLLELPHNPLATWESGQRSRGRNCIRHMRRSVY 343

  Fly   370 TALGELYARQFGTEDGRID---LDNLYDTLKTALRQSLGAEWLVEGTQRVGQEKLRNLKLQMPTY 431
            ..:..:|.|.|.:.....|   :.:::..|::.|...:             |....||...:...
  Fly   344 LPMNYVYERSFYSRRRHADELVIHSVFQQLQSQLELRV-------------QHNAFNLSQDLVKS 395

  Fly   432 ERPVILKLQLERGN---------YWQNLRQ-LLG--VVQSQRNNRLFEEFLPAPTDPVEAYEAR- 483
            .:..:.::::..||         ||.:.|: .:|  ..::..|:.|:...|.|..:.....|.|
  Fly   396 LQAKVHQMRINVGNLPPNVTEQFYWDSDRRWSVGRDFYENHLNSLLYYYTLVADLESSSDQEERD 460

  Fly   484 ------VRLRPVQRRLD-------MGLALLQP------PAYDPRYGHAIRYATLGVQLAQQLVMA 529
                  :........:|       :|..:..|      |.:|..:..|:.|..|...|..:::.|
  Fly   461 IWYSFNMHTPEFPDNIDATPYFYCLGNIIFVPYSYVKRPFFDANFWPALLYGDLANTLGHEIMHA 525

  Fly   530 FDDPHWSVGLLERDNWDGQTAWQYHIRSNCFARQ---VDNY------LRPNVSATTQLITDSAAI 585
            ||     ..|::.|.       |.::|:  |:.|   |:.|      |..:.....:..:|.:..
  Fly   526 FD-----TDLVDYDA-------QGNLRN--FSDQLGEVELYNGAVGCLNSSAVMLNERTSDVSGS 576

  Fly   586 NVAFRAYLTWLGFQEPNNDFTKLTKETLPDLNYSNTALFFLAYAQEHCSLEEARPRDEQGTPEGY 650
            .:|.:.|         ..|:  ||:.       .|..|:||.:|...|. :|.....:.|
  Fly   577 RLAMQTY---------GGDW--LTRS-------GNGRLYFLQFAHFFCG-DEGDQYHDSG----- 617

  Fly   651 LYSARQNHTWTRLLVNGPLRNSVEFASEFRCPIGSPMNPASKC 693
              |.|.|:.         |....:||..|||.:||.|..|.:|
  Fly   618 --SQRLNYA---------LGQVPQFAEVFRCHVGSGMTSADQC 649

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl14	NP_651097.1	M13	60..693	CDD:341056	140/703 (20%)
Nepl4	NP_609019.1	GluZincin	59..649	CDD:472708	140/702 (20%)