Protein Alignment Nepl14 and Nep3

DIOPT Version :10

• Sequence 1: NP_651097.1
• Gene: Nepl14 / 42700
• FlyBaseID: FBgn0039023
• Length: 696
• Species: Drosophila melanogaster
• Sequence 2: NP_523417.2
• Gene: Nep3 / 33005
• FlyBaseID: FBgn0031081
• Length: 786
• Species: Drosophila melanogaster
• Alignment Length: 763
• Identity: 178/763 - (23%)
• Similarity: 314/763 - (41%)
• Gaps: 149/763 - (19%)

  Fly    17 PHLQQNALVSGEDLPPPFQR-IYQSEQTVRRSKAQDMGSHVNKSIDPCVDFYAYACGNW------ 74
            ||  |....||.:||...:. |:.|.:.::         .::.::|||.|||.|:|..|
  Fly    90 PH--QKDCPSGNELPCLNKHCIFASSEILK---------SIDVTVDPCDDFYGYSCNQWIKNNPI 143

  Fly    75 ---KSTLTPQQQLQQQTDRELLLLVEEAVRREDSVIVRQAKELFKSCVSAQAHQSQQQQHFLSEF 136
               |||.....:|:|.....:..::|:..:...|...|:||..::||:.|..|..:.....:::.
  Fly   144 PEGKSTWGTFGKLEQMNQLIIRNVLEKPAKSFKSDAERKAKVYYESCLDADEHMEKLGAKPMNDL 208

  Fly   137 INQNGGFPAVPGSQWAVHHHDY---NWL--SVLGGLRLRYGMDILIGLRVGYNYGNVNENSLYLS 196
            :.|.||        |.|....|   ||.  ..|..|..:|..:.|.|..:|.:..|.:.:.:.:.
  Fly   209 LLQIGG--------WNVTKSGYNVANWTMGHTLKILHNKYNFNCLFGWAIGEDDKNSSRHVIQID 265

  Fly   197 EPSTLIPTELCTRNRSD-IRDSIYEPLEHRVASELKSWLALGHDESARLA--ADILSFEHELCGG 258
            :....:||.....|::| .|..:.|.:|:..    |..:.||.:||...|  ..:::||.:|...
  Fly   266 QGGLTLPTADYYNNKTDNHRKVLNEYIEYMT----KVCVLLGANESDARAQMIGVINFEKKLANI 326

  Fly   259 MKGGSFESWDAEEQLY----------LANYTRKTLREFSNSIELDLDSYVRASFGQDIYKPVYMA 313
            ..  ..|....||.:|          ||.:...| ..|.|::::     |......|....||
  Fly   327 TI--PLEDRRNEEAMYHPMQLRQLSKLAPFLNWT-DHFDNAMQM-----VGRRVTDDEVVVVY-- 381

  Fly   314 APEYFRQ-----LKRTVSAHNISLVANYIMYRAV----SALNFPLDDRPQ-LRK----------- 357
            ||::.:.     ||...:......:.||::::||    |.|:.|..|..: :||
  Fly   382 APDFLKNLSDIILKMEQTEEGKITLNNYLVWQAVRTLTSCLSKPFRDAYKGVRKALMGSDGGEEI 446

  Fly   358 -RECLERTKELLPTALGELYARQFGTEDGRIDLDNLYDTLKTALRQSL-GAEWLVEGTQRVGQEK 420
             |.|:..|..::..|:|.::.||....:.:...:.:...::.|.:.:| ...|:.:.|:....||
  Fly   447 WRYCVSDTNNVVGFAVGAIFVRQAFHGESKPAAEQMIAEIREAFKMNLQNLTWVDKQTREKAIEK 511

  Fly   421 LRNLK--LQMPTY-ERPVIL-----KLQLERGNYWQNLRQLLGVVQSQRNNRLFEEFLPAPTD-- 475
            ...:.  :..|.| ..||.|     :|.:....|::|..|:  .:.:.::|.   :.|..|.:
  Fly   512 ANQISDMIGFPDYILDPVELDKKYAELNITPNAYFENNIQV--AIYNLKSNL---KRLDQPVNKT 571

  Fly   476 -------PVEAYEARVRLRPVQRRLDMGLALLQPPAYDPRYGHAIRYATLGVQLAQQLVMAFDD- 532
                   .|.||     ..|.:.::.....:||.|.:|.....::.:..:||.:..:|..||||
  Fly   572 NWGMTPQTVNAY-----YTPTKNQIVFPAGILQTPFFDINNPKSLNFGAMGVVMGHELTHAFDDQ 631

  Fly   533 --PHWSVGLLERDNWDGQTAWQYHIRSNCFARQVDNYLRPNVSATT--------QLITDSAAINV 587
              .:...|.:.| .||.::..:::.:|.|.|||...|   .::..|        :.|.|:..:..
  Fly   632 GREYDKFGNINR-WWDSKSIERFNEKSECIARQYSGY---KMNGRTLNGKQTLGENIADNGGLKA 692

  Fly   588 AFRAYLTWLGFQEPNNDFTKLTKET----LPDLNYSNTALFFLAYAQEHCSLEEARPRDEQGTPE 648
            |:.||           ..||..::.    ||.||.:::.|||:::||..||    ...||    .
  Fly   693 AYHAY-----------QRTKSDRDVDILKLPGLNLTHSQLFFVSFAQVWCS----STTDE----T 738

  Fly   649 GYLYSARQNHTWTRLLVNGPLRNSVEFASEFRCPIGSPMNPASKCIIY 696
            ..|...:..|:.::..|.|.|.|..|||..|:|..|..|||..||.::
  Fly   739 NLLQMEKDPHSPSQFRVIGTLSNMKEFAEVFQCKPGKRMNPTEKCEVW 786

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl14	NP_651097.1	M13	60..693	CDD:341056	167/714 (23%)
Nep3	NP_523417.2	M13	123..784	CDD:341056	168/715 (23%)