Protein Alignment Nepl14 and Nep1

DIOPT Version :10

• Sequence 1: NP_651097.1
• Gene: Nepl14 / 42700
• FlyBaseID: FBgn0039023
• Length: 696
• Species: Drosophila melanogaster
• Sequence 2: NP_511056.2
• Gene: Nep1 / 31547
• FlyBaseID: FBgn0029843
• Length: 849
• Species: Drosophila melanogaster
• Alignment Length: 757
• Identity: 188/757 - (24%)
• Similarity: 314/757 - (41%)
• Gaps: 162/757 - (21%)

  Fly    27 GEDLPPPFQRIYQSEQTVRRS----KAQDMGSHVNKSIDPCVDFYAYACGNW---------KSTL 78
            |:|      .|..:::.||.:    .|.|:.|      |||.||:.||||.|         :|::
  Fly   168 GQD------NICMTQECVRTAASLLSAMDLNS------DPCEDFFQYACGTWNKMHPIPEDRSSI 220

  Fly    79 TPQQQLQQQTDRELLLLVEEAVRREDSVIVRQAKELFKSCVS-AQAHQSQQQQHFLSEFINQNGG 142
            :..:.|..|....|..::||.:...|:....:||..||||:. .|..:....:  |.:.:...||
  Fly   221 STFEVLSDQQQVILRAVLEEPIDERDNKATIKAKTFFKSCMDIPQIRKIGTGR--LKQVLQSLGG 283

  Fly   143 FPAVPGSQWAVHHHDYNW-----LSV---LGGLRLRYGMDILIGLRVGYNYGNVNENSLYLSEPS 199
            :|.:          :.||     |||   :|.|||.|...::|.|.||.:..|.:.|.|.:.:..
  Fly   284 WPVI----------ERNWSPPADLSVERLMGQLRLNYSEPVMIELYVGADDKNSSVNILQMDQLQ 338

  Fly   200 TLIPTELCTRNRSDIRDSIYEPLEHRVASELKSWLALGHDESARLAAD---ILSFEHELCGGMKG 261
            ..:|:.......|...|   ....||..:::.  |.||.| .|..||:   ::.||.:|.    .
  Fly   339 YALPSRDYYLKESSAND---RRAYHRYMTQVA--LLLGAD-PATAAAELEKVVLFETQLV----N 393

  Fly   262 GSFESWDAEEQLYLANYTRKTLREFSNSI-ELDLDSYVRASFGQDI----YKPVYMAAPEYFRQL 321
            .|....|..:...:  |.:..|.|....: |:....|::|:.|..|    .:|:......|..::
  Fly   394 VSLPEADRHDTSLV--YRKMLLPELQELVPEVQWQEYLQAALGPGIPLQEDEPLVTYGLHYLTEM 456

  Fly   322 KRTVSAHNISLVANYIMYRAV-SALNFPLD----DRPQLRK------------RECLERTKELLP 369
            .:.::..:..:|.||:::|.| |.::..:|    :|.:.||            .:|:|.|.:.|.
  Fly   457 GKILAHTDRRVVHNYMLWRLVMSLMSHMIDEYQRERVEFRKILMGIQSERTRWSQCVEWTNKKLG 521

  Fly   370 TALGELYAR-QFGTEDGRIDLDNLYDTLKTALRQSLGA-EWLVEGTQRVGQEKLRNLKLQMPTYE 432
            .|:|.|:.| .|..|...:.|:.:: |::.|..:.|.. :|:.:.|:.|.:||..::.      |
  Fly   522 VAVGALFIRDNFNQESKEVALEMIH-TIRAAFNELLAENDWMDDETRAVAKEKADSMN------E 579

  Fly   433 R---PVILKLQLERGNYWQNL--------RQLLGVVQ--SQRNNRLFEEFLPAPTD----PVEAY 480
            |   |.:|....|....:.||        ..:|.::|  |::..||..:    |.|    ..|..
  Fly   580 RIGYPELLTNATELEQEYVNLTIVPDNFINNVLSILQWESEKMLRLLRQ----PVDKEKWTTEPA 640

  Fly   481 EARVRLRPVQRRLDMGLALLQPPAYDPRYGHAIRYATLGVQLAQQLVMAFDDP-----------H 534
            .......|.:..:.....:|||..|...:..::.|..:||.:..::...|||.           .
  Fly   641 VVNAFYNPNKNDIVFPAGILQPLFYSQHFPKSLNYGGIGVVIGHEITHGFDDKGRQFDKEGNMMQ 705

  Fly   535 WSVGLLERDNWDGQTAWQYHIRSNCFARQVDNYLRPNVSATTQL----------ITDSAAINVAF 589
            |         |:..|...:..|:.|.   :|.|.|..::.....          |.|:..:..||
  Fly   706 W---------WNNATIEAFRERTQCV---IDQYSRYKINEVDMFMDGRMTQGENIADNGGLKQAF 758

  Fly   590 RAYLTWLGFQEPNNDFTKLTKETLPDLNYSNTALFFLAYAQEHCSLEEARPRDEQGTPEGYLYSA 654
            |||..|        :.....::.||.||.::..||||.|||..|.  ..||.|....    :.||
  Fly   759 RAYKKW--------ETLHGREQQLPGLNMTHDQLFFLNYAQIWCG--SMRPEDALTK----IRSA 809

  Fly   655 RQNHTWTRLLVNGPLRNSVEFASEFRCPIGSPMNPASKCIIY 696
            ..:..:.|:|  |||.||.:|||.::||:||.||||.||.::
  Fly   810 VHSPGFVRVL--GPLSNSRDFASAYKCPLGSTMNPAEKCSVW 849

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl14	NP_651097.1	M13	60..693	CDD:341056	178/715 (25%)
Nep1	NP_511056.2	M13	194..847	CDD:341056	179/715 (25%)