Protein Alignment Nepl14 and frma

DIOPT Version :10

• Sequence 1: NP_651097.1
• Gene: Nepl14 / 42700
• FlyBaseID: FBgn0039023
• Length: 696
• Species: Drosophila melanogaster
• Sequence 2: NP_572226.2
• Gene: frma / 31464
• FlyBaseID: FBgn0029769
• Length: 611
• Species: Drosophila melanogaster
• Alignment Length: 728
• Identity: 138/728 - (18%)
• Similarity: 251/728 - (34%)
• Gaps: 234/728 - (32%)

  Fly    61 DPCVDFYAYACGNWKST--------------LTPQQQLQQQTDRELLLLVEEAVRREDSV--IVR 109
            |||.:||..|||||.::              ...|::|....|.|          |||..  .::
  Fly    26 DPCQNFYKVACGNWSASHATDSYESFMDRLDYNYQEKLADLLDNE----------REDDEPHFLQ 80

  Fly   110 QAKELFKSCVSAQAHQSQQQ-----QHFLSEFINQNGGFPAVPGSQWAVHHHDYNWLSVLGGLRL 169
            |.:..:.:|   :...||.|     :|.:   :.:|            :.:.:   |||  ||..
  Fly    81 QLRNFYTAC---RKPLSQDQVLRILEHLI---VMEN------------IQNEE---LSV--GLTA 122

  Fly   170 RYGMDILIGLRVGYNYGNVNENSLY------LSEPSTLIPTELCTRNRSDIRDSIYEPLEHRVAS 228
            .:.:.:||.|         |:::.|      :|......|.   |.||        |||...:..
  Fly   123 AFRLQVLIDL---------NDSNTYDIWKQLMSHRKHWDPN---TTNR--------EPLTREMFD 167

  Fly   229 ELKSWLALGH----------DESARLAADILSFEHELCGGMKGGSFESWDAEEQL---YL----- 275
            :|  |.:|..          .|.:.|...|:|:      |.:...|:|.|...::   ::
  Fly   168 KL--WASLPKIPFPFKEYYWRELSELEEKIMSY------GSEDDGFDSGDLVTRIPPFWMMPWPN 224

  Fly   276 ANYTRKTLREFSNSIELDLDSYVRASFGQDIYKPVYMAAPEYFRQLKRTVSAHNISLVANYIMYR 340
            .|.|.:.|.:.::.:::..:.:        |...:||                .:.|||     .
  Fly   225 GNITYENLSQMAHWLDIKANEF--------ILTYIYM----------------RLKLVA-----E 260

  Fly   341 AVSALNFPLDDRPQLRKRECLERTKELLPTALGELYARQFGTEDGRIDLDNLYDTLKTALRQSLG 405
            .||..::.:|      :.:|.|:::::|......|..:..........|.:::..||....|.|.
  Fly   261 GVSTESWHID------RDQCAEQSRQILSHPAAWLVEKNHPRLKEEPVLQDIFAELKQRFGQKLL 319

  Fly   406 AEW--LVEGTQRVGQEKLRNLKLQMPTYER-----PVILKLQ-------LERGNYWQNLRQLLGV 456
            |..  ....||.....||:.::|::....|     .::.:::       :...:|:.||.  :|:
  Fly   320 ANRNNFTRSTQHFLLGKLKRMRLRLSILPRNSSAQSMVRRIERHYRDVHMNASDYFGNLH--IGL 382

  Fly   457 VQSQRNNRLFE--------EFLPAPTDPVEAYEARVR---------LRPVQRRLDMGLALLQPPA 504
            ..|:.:.:..:        :.:|:.....:.|..:||         ....|..|.:.|:||:||.
  Fly   383 NHSRSHKKYAQLWAIVFGRQLIPSRISKSDLYPTQVRGYGTYASAFYIVKQNMLIVPLSLLEPPF 447

  Fly   505 YDPRYGHAIRYATLGVQLAQQLVMAFDDPHWSVGLLERDNWDGQTAWQYHIRSNCFARQVD---- 565
            |.......:.|:.||..|..:|...||.             :|.|...:.:.|:...|::|
  Fly   448 YTHGQPSILTYSALGFILGHELSHGFDS-------------EGMTFSSHGVGSSAVDRELDRNPR 499

  Fly   566 -----NYLRPNVSATT-QLITDSAAINVAFRAYLTWLGFQEPNNDFTKLTKETLPDLNYSNTAL- 623
                 ..||....... :...|::.:.:|:.||..              |.:|....|.|...|
  Fly   500 FQQELGCLRRRFGRKRYEKFADASGLELAYSAYFD--------------TAQTDHKRNRSAEELV 550

  Fly   624 -----FFLAYAQEHCSLEEARPRDEQGTPEGYLYSARQNHTWTRLLVNGPLRNSVEFASEFRCPI 683
                 ||..:||..||.:|.....:.|:              .|..||..:.:...|...|.|
  Fly   551 TQKQQFFHNFAQFFCSDKELLQAHDHGS--------------DRKRVNDAVAHFEPFREAFSC-- 599

  Fly   684 GSPMNPASKCIIY 696
             .|.....:|.:|
  Fly   600 -GPSPRRRQCRLY 611

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl14	NP_651097.1	M13	60..693	CDD:341056	136/723 (19%)
frma	NP_572226.2	GluZincin	25..601	CDD:472708	135/716 (19%)