Protein Alignment Nepl14 and Kel

DIOPT Version :10

• Sequence 1: NP_651097.1
• Gene: Nepl14 / 42700
• FlyBaseID: FBgn0039023
• Length: 696
• Species: Drosophila melanogaster
• Sequence 2: NP_001178540.1
• Gene: Kel / 297025
• RGDID: 1565470
• Length: 713
• Species: Rattus norvegicus
• Alignment Length: 724
• Identity: 162/724 - (22%)
• Similarity: 277/724 - (38%)
• Gaps: 169/724 - (23%)

  Fly    57 NKSIDPCVDFYAYACGNWKSTLTPQQQLQQQTDRELLLLVEEAVRREDSVIVRQAKELFKSCVSA 121
            |:|..||.||:::||.....|....|.|.::....|..|:|............:|.:.:.||:..
  Rat    75 NRSAAPCTDFFSFACEKANGTSNSFQALAEENKSRLWKLLEAPGSWHLESGEEKAFQFYNSCMDT 139

  Fly   122 QAHQSQQQQHFLSEFINQNGGFPAVPGSQWAVHHHDYNWLSVLGGLRLRYGMDILIGLRVGYNYG 186
            .|.::..... |.:.|.:.||        |.:   ..||........||..|.         .||
  Rat   140 DAIEASGTGP-LVQIIKELGG--------WNI---SGNWTFFDFNQNLRLLMS---------QYG 183

  Fly   187 NVNENSLYL----SEPSTLI----PTELCTRNRSDIRDSIYEPLEHRVA---SELKSWLALGHDE 240
            :......||    :.|.|.|    ..|.....:.|....:|..:.....   :.|.:.|.....|
  Rat   184 HFPFFRAYLHPHPAPPHTPIIQIDQPEFDILLQQDQEQKVYAQILREYVTYLNRLGTLLGSNPQE 248

  Fly   241 SARLAADILSFEHELCGGMKGGSFESWDAEEQLYLANYTRKTLREFSNSIELDLDSYVRASFGQD 305
            :.:.|:..:.|...|...::  ..:...|:::|:.. .|...|:|.:.:|:.       .|..|.
  Rat   249 AQQHASWSIVFTSRLFQFLR--PQQQQQAQDKLFHV-VTIDALQEMAPAIDW-------LSCLQA 303

  Fly   306 IYKPVYMAAP--------EYFRQLKRTVS---AHNISLVANYIMYRAVSALNFP----------- 348
            |:.|:.::..        :|.|.:.:.|.   .::..::.:|::...|..|: |
  Rat   304 IFTPMSLSPSQTLQVHDLDYLRNMSQLVEEGLLNHSEIIQSYMILGLVDTLS-PALATKFQEARR 367

  Fly   349 --------LDDRPQL----RKRECLERTKELLPTALGELYARQ-FGTEDGRIDLDNLYDTLKTAL 400
                    |.:||.|    |..:|:|:|.......|..|:..: ||.......:: |:..:|.|:
  Rat   368 ELTQKLRKLKERPPLPAYPRWMKCVEQTGSFFEPTLAALFVHEAFGPSIRSAAME-LFAEIKDAV 431

  Fly   401 RQSL-GAEWLVEGTQRVGQEKLRNLKLQMPTYERPVILKLQLERGNYW------QNLRQLLGVVQ 458
            ...| ...|:.|.|::....||..|:::|...:|  .||.::.:..|.      ..|:..|..|:
  Rat   432 IVRLKKLSWISEETRKEALNKLTQLQVEMGAPKR--ALKTEMAKQEYSDIQLGPSFLQSFLSCVR 494

  Fly   459 SQRNNRLFEEFLPAP-----TDP--VEAYEA---RVRLRPVQRRLDMGLALLQPPAYDPRYGHAI 513
            |.:..::.....|.|     ..|  |.||.:   .|.:.|.        .|||||.:.|.|..|:
  Rat   495 SLQGRKVRSFLQPFPYHRWQKSPWSVSAYYSVPDHVVVFPA--------GLLQPPFFHPGYPRAV 551

  Fly   514 RYATLGVQLAQQLVMAFDDPHWSVGLLERDNWDGQTAWQYHIRSNCFA---RQVDNYL------- 568
            .:..:|..:|.:|:..|                    :|:.:...|.|   |.:...|
  Rat   552 NFGAVGSIMAHKLLHIF--------------------FQFLLPGGCPACDTRALQEALLCLEHRY 596

  Fly   569 ----RPNVSA--TTQLITDSAA----INVAFRAYLTWLGFQEPNNDFTKLTKE-TLPDLNYSNTA 622
                .|::|:  .:..:.::||    :.:||:||         ....|:.|.| |||:...|...
  Rat   597 AAFPLPSMSSFNGSHTLLENAADIGGVAIAFQAY---------RKRITERTGELTLPNQELSPYQ 652

  Fly   623 LFFLAYAQEHCSLEEARPRDEQGTPEGYLYSARQNHTWTRLLVNGPLRNSVEFASEFRCPIGSPM 687
            |||.:|||..|  .|...:|.|.|           |:..||.|:|||.||.:||..|.||.||.:
  Rat   653 LFFRSYAQVMC--RELISQDPQDT-----------HSPPRLRVHGPLSNSPDFAKHFLCPSGSLL 704

  Fly   688 NPASKCIIY 696
            ||:::|.::
  Rat   705 NPSTRCKLW 713

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl14	NP_651097.1	M13	60..693	CDD:341056	159/716 (22%)
Kel	NP_001178540.1	M13	78..711	CDD:341056	159/717 (22%)