Protein Alignment Nepl14 and nep-24

DIOPT Version :10

• Sequence 1: NP_651097.1
• Gene: Nepl14 / 42700
• FlyBaseID: FBgn0039023
• Length: 696
• Species: Drosophila melanogaster
• Sequence 2: NP_503005.3
• Gene: nep-24 / 190993
• WormBaseID: WBGene00013786
• Length: 567
• Species: Caenorhabditis elegans
• Alignment Length: 583
• Identity: 107/583 - (18%)
• Similarity: 216/583 - (37%)
• Gaps: 134/583 - (22%)

  Fly    49 AQDMGSHVNKSIDPCVDFYAYACGN----------WKSTLTPQQQLQQQTDRELLLLVEEAVRRE 103
            |..:.::.:.|:|||.:|:.:|||.          .|.|.|....:::      .|...|..|.:
 Worm    47 AHMLHNYHDPSVDPCDNFHQFACGREHEHETEDIYTKKTKTINNIMKR------FLKKNETSRSK 105

  Fly   104 DSVIVRQAKELFKSCVSAQAHQSQQQQHFLSEF---INQNGGFPAVPGSQWAVHHHDYNWLSVLG 165
            ....:|   .|:|:|.:.:.:.:..:...|.:.   |...|.:|.| ..:|.....|.|
 Worm   106 SENAMR---TLYKACKTLEKNSTASRNKALQDIFQDIQSIGAWPVV-DDKWDESKFDLN------ 160

  Fly   166 GLRLRYGMDILIGL-RVGYNYGNVNENSLYLSEPSTLIPTELCTRNRSDIRDSIYEPLEHRVASE 229
                    |.|:.| |:|.....:.:.:.|::..:..|..|...|:..|:..:|.|.|:   |:.
 Worm   161 --------DFLVNLVRLGRKNFGLFQMARYVNVRNFAIGPEAAWRHNVDLGKTISEILK---ANS 214

  Fly   230 LKSWLALGHDESARLAADILSF--------EHELCGGMKGGSFESWDAEEQLYLANYTRKTLREF 286
            :::       .:.:|..|:..:        :|:......|..|.  :..:.:...|::|
 Worm   215 VQT-------NNKKLLDDLAEYVNLEKALSQHKFNTVQPGYIFS--ERSDFVSSVNFSR------ 264

  Fly   287 SNSIELDLDSYVRASFGQDIYKPVYMAAPEYF----RQLKRTVSAHNISLVANYIMYR----AVS 343
               :.|::.|..:.:...::|:.:|:.....|    ..|:..:...:...:|||::::    :::
 Worm   265 ---LVLEMMSPDKRTLFPEVYQIMYLTNTSLFFGKNNNLETIIRNTSKRALANYLIFKFIDTSIA 326

  Fly   344 ALNFPLDDRPQLRKRECLERTKELLPTALGELYARQFGTEDGRIDLDNLYDTLKTALRQSLGA-E 407
            .|.:   ..|   ...|.::....||.|....:.|.|.:::.|..:..|.:..:..|.:.:|| :
 Worm   327 DLTY---GSP---SAFCEQKVINFLPRAALRAFYRNFISKENRKKITKLTEATQVQLLKIIGATD 385

  Fly   408 WLVEGTQRVGQEKL--RNLKLQMPTYERP------VILKLQLERGN-YWQNLRQLLGVVQSQRNN 463
            |:...::::..:::  .|:.:..|.|..|      :...|.|...: |:..:|::         |
 Worm   386 WMSIKSKKIAMDRVSSMNMVIGYPDYFDPPGKLDGLFEHLNLSSSDTYYTVVRKI---------N 441

  Fly   464 RLFEEFLPAPTDPVEAYEARVRLRPVQRRL---------DMGLALLQP----PAYDPRYGHAIRY 515
            |...|      ..::.|...|...|:...|         |..|.:..|    |.:|..:......
 Worm   442 RFMRE------QEMDYYTGEVPYYPLFPGLMTNAMYNANDNNLMIFAPFFDDPFFDSSFPDYANI 500

  Fly   516 ATLGVQLAQQLVMAFDDPHWSVGLLERDNWDGQT-AW-------QYHIRSNCFARQVDNYLRP 570
            |.....||.::...| .||.      .|...|.| .|       :|..|..|...|...|..|
 Worm   501 AFTSNTLAHEMGHTF-SPHL------MDIMTGTTEVWLTPKETEEYEKRVKCLEDQYTEYDDP 556

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl14	NP_651097.1	M13	60..693	CDD:341056	105/572 (18%)
nep-24	NP_503005.3	GluZincin	58..561	CDD:472708	105/572 (18%)