Protein Alignment Nepl14 and nep-10

DIOPT Version :10

• Sequence 1: NP_651097.1
• Gene: Nepl14 / 42700
• FlyBaseID: FBgn0039023
• Length: 696
• Species: Drosophila melanogaster
• Sequence 2: NP_494532.2
• Gene: nep-10 / 173684
• WormBaseID: WBGene00017555
• Length: 711
• Species: Caenorhabditis elegans
• Alignment Length: 796
• Identity: 169/796 - (21%)
• Similarity: 286/796 - (35%)
• Gaps: 218/796 - (27%)

  Fly     9 VFLWLLWLPHLQQNALV-----SGEDLP--PPFQR---IYQSEQTVRRSK-----------AQDM 52
            |||.|:.: |::....|     |.:.||  .|.|:   |....|||...:           |.::
 Worm    26 VFLALVTV-HIKMTIDVAPVFKSDDPLPRGDPDQKPATIDSETQTVDEPRNVCESPECITLAHEL 89

  Fly    53 GSHVNKSIDPCVDFYAYACGNW-------KSTLTPQQQLQQQTDRELLLLVEEAVRREDSVIVRQ 110
            .::.:.|:|||.|||.:.||.:       :..:..::....:..||.||..:.:..:.::.:
 Worm    90 HNYKDPSVDPCQDFYQHFCGKFYEHSAIGQGRMATKRSTLSKLIREFLLKNKTSTSKSENTM--- 151

  Fly   111 AKELFKSCVSAQA---HQSQQQQHFLSEF--INQNGGFPAVPGSQWAVHHHDYNWLSVLGGLRLR 170
             |:::..|...|.   ..|...|..|..|  |.:.|.:|.:          |.:|..      .:
 Worm   152 -KQVYAKCRELQKISDLNSIPPQALLDIFSDIKKIGAWPVL----------DKDWDG------SK 199

  Fly   171 YGMDILIGLRVGYNYGNVNENSL------YLSEPSTLIPTELCTRNRSDIRDSIYEPLEHRV--A 227
            :.::.::...|     |:.|..|      :::.|..||...|    :..::.|:.|.:...:  |
 Worm   200 FNLNEMLRQLV-----NLGETHLGFFHFDFIARPYVLIKPPL----KQGVQKSVLEKVVKMILEA 255

  Fly   228 SELKSWLALGHDESARLAADILSFEHELCGGMKGGSFESWDAEEQLYLANYTR-KTLREFSNSIE 291
            :|:|                           |..|..|  |.:|...|:|..: ..|...|.||.
 Worm   256 NEIK---------------------------MDQGFSE--DLDEYFELSNRIKIDKLPRTSRSIV 291

  Fly   292 LDLDSYVRASF-----------------GQDIYKPVYMAAPEYFR-----QLKRTVSAHNISLVA 334
            ..|....|.:|                 |....|.|....|.:.|     .|...:.:.:...:|
 Worm   292 GLLPDVRRINFRGLILEMMPRSKMNRFLGTLFQKVVTYHHPLFVRDNETNHLDTIIRSTSNRALA 356

  Fly   335 NYIMYR----AVSALNFPL-DDRPQLRKRECLERTKELLPTALGELYARQFGTEDGRIDLDNLYD 394
            ||:::.    ::..|.|.| .||     ..|.:...:.||.....::.|....:..|.::..|.:
 Worm   357 NYLIFNFIHSSIKFLTFGLKSDR-----ERCEKIVVQELPRPSLRVFMRNCVDKGNREEVAKLTE 416

  Fly   395 TLKTALRQSLGAEWLVEGTQRVGQEKLRNLK--------LQMPT-YERPVIL-----KLQLERGN 445
            |:|..:     .|.:.|........|.|.||        :..|. ::.|..|     .|.|:..:
 Worm   417 TVKENV-----LEMIRESDSFTPSVKKRVLKKVEAIGAIIGYPDHFDPPGTLDKEYENLTLDASD 476

  Fly   446 YWQNLRQLLGVVQSQRNNRLFEEFLP-----APTDPVEAYEARVRLRPVQRRLDMGLALLQP--- 502
            .:..:.|.|..::.|..    .|||.     :|:|.|....|....:      |..|.:|.|
 Worm   477 SYYKMSQKLHQLRLQHQ----MEFLAGQTPLSPSDQVLEVNAHYDSK------DNALTVLAPFLD 531

  Fly   503 -PAYDPRYGHAIRYATLGVQLAQQLVMAFDDPHWSVGLLERDNW-DGQTAWQYHIRSNCFARQVD 565
             |.:|..|...:.....|..:..:...:.|..     :|.||.| ..:...:|..|:.|...|.|
 Worm   532 DPFFDSTYPEYVNLIFTGFLIGHEFGHSIDPK-----ILRRDGWYKTEDMTEYGKRAQCLIDQYD 591

  Fly   566 NYLRPN----VSAT---TQLITDSAAINVAFRAYLTW--------LGFQEPNNDFTKLTKETLPD 615
            ||..|:    ::.|   .:::.|....:|.:||:...        :||::.|          |..
 Worm   592 NYDDPDHGKQMNGTYCIGEIVGDWVGRDVTWRAFKKMDLSKMQKLIGFEDKN----------LDQ 646

  Fly   616 LNYSNTALFFLAYAQEHCSLEEARPRDEQGTPEGYLYSARQNHTWTRLLVNGPLRNSVEFASEFR 680
            |.:...:|||       |.     ||..:...:  |.|  ..|......|||...|..:||..|.
 Worm   647 LYFRIQSLFF-------CG-----PRSMKSLEQ--LLS--DPHPTEVFRVNGIYSNMPQFAKAFN 695

  Fly   681 CPIGSPMNPASKCIIY 696
            |||||||||..||.::
 Worm   696 CPIGSPMNPEKKCKMF 711

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl14	NP_651097.1	M13	60..693	CDD:341056	150/719 (21%)
nep-10	NP_494532.2	M13	97..709	CDD:341056	151/720 (21%)