Protein Alignment Nepl14 and Nep5

DIOPT Version :10

• Sequence 1: NP_651097.1
• Gene: Nepl14 / 42700
• FlyBaseID: FBgn0039023
• Length: 696
• Species: Drosophila melanogaster
• Sequence 2: XP_061503273.1
• Gene: Nep5 / 1273520
• VectorBaseID: AGAMI1_014349
• Length: 834
• Species: Anopheles gambiae
• Alignment Length: 816
• Identity: 166/816 - (20%)
• Similarity: 286/816 - (35%)
• Gaps: 214/816 - (26%)

  Fly    32 PPFQRIYQSEQTVRRSKAQDMGSHVNKSIDPCVDFYAYACGNWKSTLTPQQQLQQQTD------R 90
            ||  .|..|...:|.:.|  :...::.::|||.|||.||||||:.. .|:.......|      .
Mosquito    82 PP--EICHSADCLRSAAA--LKHSMDLTVDPCEDFYQYACGNWEDE-HPRPDTYVSFDWFSERQA 141

  Fly    91 ELLLLVEEAVRREDSVI----VRQAKELFKSCVSAQA-----------HQSQQQQHFLSEFINQN 140
            ::|..:...::...|.:    |.||:.::.:|::..|           :..|.|.......:|..
Mosquito   142 KILRNIRHYLQANSSALDPKPVVQARTMYAACLNLTAMDRLGYGPVFKYLKQFQLPPYPSLLNVT 206

  Fly   141 GGFPAVPGSQWAVHHHDYNWLSVLGGLRLRYGMDILIGLRVGYNYGNVNENSLYLSEPSTLIPTE 205
            .|    |.|. ....:.::|:..|..::...||||.|||.|..:..:.:.|.|.|..|
Mosquito   207 EG----PASA-TFQGYGFDWVKSLAKIKQLLGMDIFIGLDVYPDPRHRDYNRLVLGTP------- 259

  Fly   206 LCTRNRSDIRDSIYEPLEHRVASELKSWLALGHDESARLAAD-------------ILSFEHELCG 257
               .:.||:..:. :.|.|......:..|.:..|:.|...:|             :.:::..:.|
Mosquito   260 ---ESGSDLPFNT-DILRHIRRGRTRRKLMVSADDEADGESDGEEVEDADDEVGPLTAYKKFMIG 320

  Fly   258 GMK---------------GGSFE-------------------------SWDAEEQLYLANYTRKT 282
            .||               ...||                         |.:.|::|.|.:....|
Mosquito   321 VMKLLVNSTDPTIKVESFNAQFERAATIVVQFSDSISKFNREAENASRSTNVEDRLNLQDIVYYT 385

  Fly   283 LREFSNSIELDLDSYVRASFGQDIYKPVYMAAPE------------------YFRQLKRTVSAHN 329
            :.:..|..:..|.........:.:...|:...||                  |.:.|...::...
Mosquito   386 VADLQNITDTHLAPKDPLPIWERLLASVFEGIPEAQLNLQDELILTSNADLLYLKLLVDYLAVTP 450

  Fly   330 ISLVANYIMYRAVSAL-----------------NFPLDDRPQLRKRECLERTKELLPTALGELYA 377
            ::.:..||.:..|..|                 :....|....|...|......||..|:....:
Mosquito   451 LAHIELYIWWTVVEELILHTTLEVRKLYYDYYKSIAPSDGFSSRTLYCTGTVNRLLGMAVSYAIS 515

  Fly   378 RQFGTEDGRIDLDNLYDTLKTA----LRQSLGAEWLVEGTQRVGQEKLRNLKLQMPTYERPVILK 438
            ....|.|.:..:.::...::||    :|.:...:|..:.:.....:.:|:| :..|.:    ||.
Mosquito   516 SDNFTRDTKPRVQDMLRYIRTAFEGLVRDTTWMDWPTKQSTLRKSQAMRSL-IGFPDW----ILD 575

  Fly   439 ----------LQLERGNYWQNLRQLLGVVQSQRNN-----------RLFEEFLPAPTDPVEAYEA 482
                      ||:....:.:|:.|     :.||.|           .|..|.||...:....::
Mosquito   576 HRELEQHYSGLQVNESTHLENMMQ-----EVQRKNIIKLRRWRQKHELSWETLPTNVNAFHTFQ- 634

  Fly   483 RVRLRPVQRRLDMGLALLQPPAYDPRYG-HAIRYATLGVQLAQQLVMAFDDPHWSVGLLERDN-- 544
                   :..:.:.:|:||.|.|  ..| .|:.|..||..|..:|...|||   |....::|.
Mosquito   635 -------ENAITIPIAILQYPFY--HLGLEALNYGALGTILGHELTHGFDD---SGRQFDKDGNL 687

  Fly   545 ---WDGQTAWQYHIRSNCFARQVDNYLRPNVS-------ATTQLITDSAAINVAFRAYLTWL--G 597
               |..:|..:|..|:.||..|...|..|...       ...:.|.|:..:..|||||..::  |
Mosquito   688 AQWWTDRTVQEYVNRTKCFVSQYSRYYIPEADDYIDGLLTLGENIADNGGVREAFRAYQLYVKNG 752

  Fly   598 FQEPNNDFTKLTKETLPDL-NYSNTALFFLAYAQEHCSLEEARPRDEQGTPEGYLYSARQNHTWT 661
            .::|          .||.. :|::..|||::|....|.      ...|...:.||   ..:|...
Mosquito   753 GKDP----------LLPGFEHYTHEQLFFISYGNIWCE------SHTQAAAKAYL---DDSHCPG 798

  Fly   662 RLLVNGPLRNSVEFASEFRCPIGSPMNPA-SKCIIY 696
            :..:.|.|.||.||:..|.|..|:.|||. .||.|:
Mosquito   799 KFRLKGVLTNSPEFSQTFGCKPGTEMNPGKDKCRIW 834

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl14	NP_651097.1	M13	60..693	CDD:341056	157/783 (20%)
Nep5	XP_061503273.1	None