Protein Alignment Nepl14 and Eef1ece2

DIOPT Version :10

• Sequence 1: NP_651097.1
• Gene: Nepl14 / 42700
• FlyBaseID: FBgn0039023
• Length: 696
• Species: Drosophila melanogaster
• Sequence 2: NP_808810.1
• Gene: Eef1ece2 / 110599584
• MGIID: 6121518
• Length: 910
• Species: Mus musculus
• Alignment Length: 731
• Identity: 157/731 - (21%)
• Similarity: 279/731 - (38%)
• Gaps: 165/731 - (22%)

  Fly    56 VNKSIDPCVDFYAYACGNW---------KSTLTPQQQLQQQTDRELLLLVEEAVRREDSVIVRQA 111
            :::.:.||.|||.::||.|         :|.......|..|....|..|:|.......|...|:.
Mouse   255 LDRGVSPCQDFYQFSCGGWIRRNPLPNGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAERKT 319

  Fly   112 KELFKSCVSAQAHQSQQQQHF----LSEFINQNGGFPAVPGSQWAVHHHDYNWLSVLGGLRLRYG 172
            :..:.||:     ||::.:..    |.:.|::.||:...  ..|    .:.:::.||..:...|.
Mouse   320 RSFYLSCL-----QSERIEKLGAKPLRDLIDKIGGWNIT--GPW----DEDSFMDVLKAVAGTYR 373

  Fly   173 MDILIGLRVGYNYGNVNENSLYLSEPSTLIPTELCTRNRSDIRDSIYEPLEHRVASE--LKSWLA 235
            ......:.|..:..:.|.|.:.:.:....:|:          ||...    :|.|:|  |.::|
Mouse   374 ATPFFTVYVSADSKSSNSNIIQVDQSGLFLPS----------RDYYL----NRTANEKVLTAYL- 423

  Fly   236 LGHDESARLAADILSFEHELCGGMKGGSFESWD--AEEQLYLANYT-----RK------------ 281
               |....|..        |.||....:.|...  .|.::.|||.|     |:
Mouse   424 ---DYMVELGV--------LLGGQPTSTREQMQQVLELEIQLANITVPQDQRRDEEKIYHKMSIS 477

  Fly   282 TLREFSNSIE-LDLDSYVRASFGQDIYKPVYMAAPEYFRQLKRTVSAHNISLVANYIMYRAVSAL 345
            .|:..:.::: |:..|::.:.......:||.:...||.:|:...::....|::.||:::..|...
Mouse   478 ELQALAPAVDWLEFLSFLLSPLELGDSEPVVVYGTEYLQQVSELINRTEPSILNNYLIWNLVQKT 542

  Fly   346 NFPLDDRPQL------------------RKRECLERTKELLPTALGELYARQFGTEDGRIDLDNL 392
            ...||.|.:.                  |.:.|:..|.:.|..|||.|:.:.......:...:.:
Mouse   543 TSSLDQRFETAQEKLLETLYGTKKSCTPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGM 607

  Fly   393 YDTLKTALRQSLG-AEWLVEGTQRVGQEKLRNL--KLQMPTYERPVILK----------LQLERG 444
            .:.:::|..::|| ..|:.|.|:...:||...:  .:..|.:    ||:          .::...
Mouse   608 INEIRSAFEETLGDLVWMDEKTRLAAKEKADAIYDMIGFPDF----ILEPKELDDVYDGYEVSED 668

  Fly   445 NYWQNLRQLLG----VVQSQRNNRLFEEFLPAPTDPVEAYEARVRLRPVQRRLDMGLALLQPPAY 505
            :::||:..|..    |:..|.......:........|.||     ..|.:..:.....:||.|.|
Mouse   669 SFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAY-----YLPTKNEIVFPAGILQAPFY 728

  Fly   506 DPRYGHAIRYATLGVQLAQQLVMAFDD------------PHWSVGLLERDNWDGQTAWQYHIRSN 558
            ...:..|:.:..:||.:..:|..||||            |.|..        :..||:|.|  :.
Mouse   729 AHNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQN--------ESLTAFQNH--TA 783

  Fly   559 CFARQVDNYL----RPN-VSATTQLITDSAAINVAFRAYLTWL---GFQEPNNDFTKLTKETLPD 615
            |...|...|.    |.| :....:.|.|:..:..|:.||..||   |.::|           ||.
Mouse   784 CMEEQYSQYQVNGERLNGLQTLGENIADNGGLKAAYNAYKAWLRKHGEEQP-----------LPA 837

  Fly   616 LNYSNTALFFLAYAQEHCSLEEARPRDEQGTPEGYLYSARQNHTWTRLLVNGPLRNSVEFASEFR 680
            :..:|..|||:.:||..||:     |..:.:.||.:   ...|:..|..|.|.|.||.:|...|.
Mouse   838 VGLTNHQLFFVGFAQVWCSV-----RTPESSHEGLV---TDPHSPARFRVLGTLSNSRDFLRHFG 894

  Fly   681 CPIGSPMNPASKCIIY 696
            ||:||||||...|.::
Mouse   895 CPVGSPMNPGQLCEVW 910

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl14	NP_651097.1	M13	60..693	CDD:341056	156/722 (22%)
Eef1ece2	NP_808810.1	UbiG	46..>128	CDD:441829
		M13	259..908	CDD:341056	156/723 (22%)