Protein Alignment Nepl14 and ecel1

DIOPT Version :10

• Sequence 1: NP_651097.1
• Gene: Nepl14 / 42700
• FlyBaseID: FBgn0039023
• Length: 696
• Species: Drosophila melanogaster
• Sequence 2: XP_012818808.2
• Gene: ecel1 / 100496473
• XenbaseID: XB-GENE-989944
• Length: 764
• Species: Xenopus tropicalis
• Alignment Length: 726
• Identity: 158/726 - (21%)
• Similarity: 291/726 - (40%)
• Gaps: 133/726 - (18%)

  Fly    44 VRRSKAQDMGSHVNKSIDPCVDFYAYACGNW-KSTLTPQQQL---------QQQTDRELLLLVEE 98
            :|.||.  :.::::.:|.||.|||::|||.| :....|:.:|         :|..::...||::.
 Frog    99 MRASKF--ITNNIDPTISPCTDFYSFACGGWLRRHGIPEDKLIYGTIAAIGEQNEEKLEHLLLQP 161

  Fly    99 AVRREDSVIVRQAKELFKSCVSAQAHQSQQQQHFLSEFINQNGGF--PAVPGSQWAVHHHDYNWL 161
            ..|:......|:.||.||||::.:.......:..| :.|...||:  |..|.:||     |:|
 Frog   162 VRRKHKGSAERKVKEFFKSCLNMRDIDRLGARPML-QVIEDCGGWDLPEDPRTQW-----DFN-- 218

  Fly   162 SVLGGLRLRYGMDILIGLRVGYNYGNVNENSLYLSEPSTLIPTELCTRNRSDIRDSIYEPLEHRV 226
            .:|...:..|...:...:.|..:..|.:...:.:.:....:|.......:.:  :||      :|
 Frog   219 ELLYKTQGVYSTAVFFSMTVSLDDKNSSRYIIRIDQDGLTLPERTLYLGQDE--ESI------KV 275

  Fly   227 ASELKSWL-----ALGHDESARLAADILSFEHELCGGMKGGSFESWDAEEQLYLANYTRKTLREF 286
            ....|.::     .||.:...:.|.:||..|..|    ...:...:|...:.....|.:.||.:.
 Frog   276 LEAYKVFMQTILSLLGVENVQKKAEEILHLEQHL----SNITISEFDDMRRDISTMYNKVTLAQL 336

  Fly   287 SN-SIELD----LDSYVRASFGQDIYKPVYMAAPEYFRQLKRTVSAHNISLVANYIMYRAVSALN 346
            .. :..|:    |:.....:|.:|  :.|.:.|.:|.:::...:.:...|::.||:::|.|..|:
 Frog   337 QQITPHLNWKNLLNRIFHTNFPED--EEVVVLATDYMQKVSEMIRSTPASVLHNYMLWRIVVVLS 399

  Fly   347 FPL-----DDRPQLRK------------RECLERTKELLPTALGELYARQFGTEDGRIDLDNLYD 394
            ..|     |...:|.|            :.||.:..:....|||.|:..::.:...:..:..|.:
 Frog   400 EHLSTPFRDAIHELSKEMEGSEKQAELTKVCLTQANKHFGMALGALFVEEYFSSSSKAKVQQLVE 464

  Fly   395 TLKTALRQSL-GAEWLVEGTQRVGQEKLRNLKLQMPTYERPVIL----------KLQLERGNYWQ 448
            .:|..|...| ..:|:...|::..:|||::: :.|..|  |.:|          :.::....|::
 Frog   465 NIKHILDYRLEELDWMDTETKQAAREKLKHM-MVMIGY--PDVLLQPESMDKEYEFEVNEKTYFK 526

  Fly   449 NLRQLLGVVQSQRNNRLFEEFLPA----PTDPVEAYEARVRLRPVQRRLDMGLALLQPPAYDPRY 509
            |:...:.........|:.:|...:    |...:.||     ..|.:.::.....:|||..|||.:
 Frog   527 NILNSIRYSIKMAVRRIRQEVDKSAWLLPPQALNAY-----YLPNKNQMVFPAGILQPTLYDPDF 586

  Fly   510 GHAIRYATLGVQLAQQLVMAFDDPHWSVGLLERDNWDGQ-------TAW-------QYHIRSNCF 560
            ..::.|..:|..:..:|...:||            |.||       ..|       ::..::.|.
 Frog   587 PQSLNYGGIGTIIGHELTHGYDD------------WGGQYDANGNPIQWWTEDSYSKFLKKAECI 639

  Fly   561 ARQVDNYLRPN--VSATTQL---ITDSAAINVAFRAYLTWLGFQEPNNDFTKLTKETLPDLNYSN 620
            ....:|:...|  |:..|.|   |.|...:.:|:.||..|:....|        :..||.|.|::
 Frog   640 VDLYENFTVYNQRVNGRTTLGENIADLGGLKLAYYAYQKWVRDNGP--------ERPLPRLKYTH 696

  Fly   621 TALFFLAYAQEHCSLEEARPRDEQGTPEGYLYSARQNHTWTRLLVNGPLRNSVEFASEFRCPIGS 685
            ..|||:|:||..|.     .|..|..   ||......|......|.|.:....||...|.||..|
 Frog   697 DQLFFIAFAQNWCI-----KRRSQSI---YLQVLTDKHAPEHYRVMGSVSQFEEFGRVFHCPRNS 753

  Fly   686 PMNPASKCIIY 696
            ||||..||.::
 Frog   754 PMNPVHKCSVW 764

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl14	NP_651097.1	M13	60..693	CDD:341056	153/705 (22%)
ecel1	XP_012818808.2	M13	113..762	CDD:341056	154/706 (22%)