Protein Alignment Nepl14 and ece1

DIOPT Version :10

• Sequence 1: NP_651097.1
• Gene: Nepl14 / 42700
• FlyBaseID: FBgn0039023
• Length: 696
• Species: Drosophila melanogaster
• Sequence 2: XP_031762312.1
• Gene: ece1 / 100485607
• XenbaseID: XB-GENE-1014218
• Length: 782
• Species: Xenopus tropicalis
• Alignment Length: 786
• Identity: 178/786 - (22%)
• Similarity: 303/786 - (38%)
• Gaps: 168/786 - (21%)

  Fly     5 CWTT------------------VFLWLLWLPHLQQNALVSGEDLPPPFQRIYQSEQTVRRSKAQD 51
            ||..                  :|:.||.|....:|:           .|:..||..:  |....
 Frog    71 CWAERTHVEKRLLVLVVLLSLGLFMCLLALSLQYRNS-----------HRVCLSESCI--SVTSS 122

  Fly    52 MGSHVNKSIDPCVDFYAYACGNW-KSTLTPQ--------QQLQQQTDRELLLLVEEAVRREDSVI 107
            :...:::|.|||.|||.|:||.| |....|.        .:|.:.....:..|:|.:....:|..
 Frog   123 ILRSLDRSADPCQDFYQYSCGGWIKGNPVPDGHSRWGTFNELWEHNQATMKHLLENSTIETNSTA 187

  Fly   108 VRQAKELFKSCVSAQAHQSQQQQHFLSEFINQNGGFPAVPGSQWAVHHHDYNWLSVLGGLRLRYG 172
            .|:|:..|::|:: :....:.....|.:.|.:.||: |:.| .|   ..| |:...|..:...|.
 Frog   188 ERKAQRYFQACMN-ETKIEELGAKPLQDLIQKLGGW-AITG-PW---DRD-NFQETLQLVTAHYR 245

  Fly   173 MDILIGLRVGYNYGNVNENSLYLSEPSTLIPTELCTRNRSDIRDSIYEPLEHRVASELKSWLALG 237
            ......:.|..:..|.|.|.:.:.:....:|:.....|::
 Frog   246 TSPFFSVFVSADSKNSNSNVIQIDQSGLGLPSREFYLNKT------------------------- 285

  Fly   238 HDESARLAADILSFEHELCGGMKGGSFESWDAEEQLY--------LANYT-----RKTLREFSNS 289
              |:.::....|:|..:| |.:.||:..|  ..||:.        |||.|     |:...:..:.
 Frog   286 --ENEKVLTGYLNFMIQL-GVLLGGAENS--TREQMQEILDFETTLANITIPQEKRRDEEQIYHK 345

  Fly   290 IEL-DLDSYVRA----SFGQDIY--------KPVYMAAPEYFRQLKRTVSAHNISLVANYIMYRA 341
            :.. :|...|.|    .|.|.::        :||.:.|.||...:...:::.:..::.||:|:..
 Frog   346 MAAGELKDLVPAVDWMPFLQTVFYPVAINESEPVVVYAKEYLVAVSGLINSTDKRILNNYMMWNL 410

  Fly   342 VSALNFPLDDRPQ-----------LRKRECLER-------TKELLPTALGELYARQFGTEDGRID 388
            |...:..||.|.|           ..|:.||.|       |...|..|||.::.:....|:.::.
 Frog   411 VRKASSFLDQRFQDAEEKLMEVMYGTKKTCLPRWKFCISDTDNNLGFALGAMFVKATFAENSKLQ 475

  Fly   389 LDNLYDTLKTALRQSLGA-EWLVEGTQRVGQEKLRNL--KLQMPTY------------ERPVILK 438
            ...:...:|.|..::|.. .|:.:.|:|..:||...:  .:..|.:            :..|...
 Frog   476 ALKMIKEIKAAFEENLSTLTWMDDETRRAAREKAEAIYDMIGYPNFIMDPKELDKVFNDYNVTSD 540

  Fly   439 LQLERGNYWQNLRQLLGVVQSQRNNRLFEEFLPAPTDPVEAYEARVRLRPVQRRLDMGLALLQPP 503
            ...|.|..:.|....:...|.::.....:..:..||  |.||.:     |.:..:.....:||.|
 Frog   541 FYFENGMRFYNFSARVTADQLRKAPSKDQWSMTPPT--VNAYYS-----PTKNEIVFPAGILQAP 598

  Fly   504 AYDPRYGHAIRYATLGVQLAQQLVMAFDD---PHWSVGLLERDNWDGQTAWQYHIRSNCFARQVD 565
            .|......|:.:..:||.:..:|..||||   .:...|.| |..|...:...:..::.|...|..
 Frog   599 FYTSSSPTALNFGGIGVVMGHELTHAFDDQGREYDKDGNL-RPWWKNASVEAFKKQTECITEQYG 662

  Fly   566 NYL---RPNVSATT--QLITDSAAINVAFRAYLTWLGFQEPNNDFTKLTKETLPDLNYSNTALFF 625
            ||.   .|.....|  :.|.|:..:..|:|||..|:   ..|.     .::.||.|..||..|||
 Frog   663 NYTVNGEPVNGRQTLGENIADNGGLKAAYRAYKNWV---RKNG-----AEQLLPSLGLSNDQLFF 719

  Fly   626 LAYAQEHCSLEEARPRDEQGTPEGYLYSARQNHTWTRLLVNGPLRNSVEFASEFRCPIGSPMNPA 690
            :.:||..||:     |..:.:.||.:   ...|:.:|..|.|.:.||.|||..||||.||||||.
 Frog   720 VGFAQVWCSV-----RTSESSHEGLI---TDPHSPSRFRVIGSVSNSQEFAEHFRCPPGSPMNPR 776

  Fly   691 SKCIIY 696
            :||.::
 Frog   777 NKCEVW 782

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl14	NP_651097.1	M13	60..693	CDD:341056	164/708 (23%)
ece1	XP_031762312.1	M13	131..780	CDD:341056	165/709 (23%)