Protein Alignment Nepl13 and ece2b

DIOPT Version :10

• Sequence 1: NP_651096.1
• Gene: Nepl13 / 42699
• FlyBaseID: FBgn0039022
• Length: 741
• Species: Drosophila melanogaster
• Sequence 2: XP_073779419.1
• Gene: ece2b / 793465
• ZFINID: ZDB-GENE-131120-140
• Length: 800
• Species: Danio rerio
• Alignment Length: 768
• Identity: 181/768 - (23%)
• Similarity: 315/768 - (41%)
• Gaps: 158/768 - (20%)

  Fly    56 IATDVQKYMNLSADPCTDFFEYACGQWGRYHKRQLRPDELSTAQQLMETKISEQLQQLLTQPLPP 120
            :|:.:.:.::.|||||.||::||||.|.|  |..| ||..|.....  ..|.:|.|.:|...|
Zfish   109 VASKIVEALDRSADPCQDFYQYACGGWVR--KNPL-PDGRSRWSTF--NSIWDQNQAVLKHLL-- 166

  Fly   121 QHHPNGYSGASMTNVRKVRAFYESCVAVEANASERRRFLMKILKDNGGLRNVPNSNWQHNRQWVQ 185
               .||...:|....||.:::|.||:..:.......:.||.::...||        |.....|.
Zfish   167 ---ENGTFNSSSEAERKTQSYYLSCLNEQRIEELGAQPLMDLITKIGG--------WNITESWD- 219

  Fly   186 TLGELRRNYGLDIL------------LGLEIDLNLQTMKGNTIYFGEPKLTIIPAEHCNALATRG 238
                 :.|: ||:|            ..:.:.::.:....|.|...:..| .:|:
Zfish   220 -----KENF-LDVLKIISGPYRAQPFFTVSVSVDPKNSNSNVIQVDQSGL-FLPS---------- 267

  Fly   239 AQVRDEVYELVQQQVTENLRDW-------FGMDTGEAARFAGDIIRFEFELCKQMGEQDIQKPEE 296
               ||.......::|.:...|:       .|.|..........|:.||..|.      :|..|::
Zfish   268 ---RDYYLNKTNEKVLKAYLDYMVELGLLLGGDKNSTRGQMQQILDFETALA------NITVPQD 323

  Fly   297 EFPPAIQAQIYGARSRTGQERLRRQKGGMTLTEL-----TSEMGNHLDFKMLVEVILESQYPSQV 356
            |              |..:|::..:   :|:.:|     ..|..::|: .:|..:.|....|..|
Zfish   324 E--------------RRDEEKIYHK---ITIADLQVLAPAIEWLDYLN-SVLSPLELNDTEPVVV 370

  Fly   357 YLRSPEYVKHVVRTVKANNRITVGGYILY----VALNELNQPPEEAPSQ--------------RA 403
            |.:  ||::.|...:...:...:..|:::    ...:.|:|..|.|..:              |.
Zfish   371 YAK--EYMQQVSELINKTDHSLLNNYMIWNLVQKGASSLDQRFENAQDKLLESLYGTKKSCTPRW 433

  Fly   404 RQCVQVTQRLFPQVLGEMFQRHVQRDNAK---------------------HDL--------DAVF 439
            :.|:..|.......||.:|.:......:|                     |:|        :.:.
Zfish   434 QTCIGNTDDTLGFALGALFVKATFDKQSKEIDLNGGAFLPSCGRNVNSTVHNLMFSVITQAEGMI 498

  Fly   440 NDVIKALEEQF-HVEWMDENDRRAARTRLSQY--RVSLPDY--QSLDLTDLQ--FQKSED-YWRR 496
            |::..|.:... .::||||..|:||:.:....  .:..||:  .|.:|.|:.  ::.:|| :::.
Zfish   499 NEIRTAFKGALDDLKWMDEQTRQAAKDKADAIYDMIGFPDFILDSKELDDVYDGYEVTEDNFFQN 563

  Fly   497 LEIALKYRSHQQFEALRGNDFGQDADGLDAFEVRAALSPRQQMVLVGWGLLQAPYYNYYYPKSLK 561
            :.....:.:....:.|| ....:|...:....|.|...|.:..::...|:||||:|...:||:|.
Zfish   564 MINFYNFSARVMADQLR-KPPNRDQWSMTPPTVNAYYMPTKNGIVFPAGILQAPFYAQDHPKALN 627

  Fly   562 YALLGHRLASALVQAFDDEG--WNNHPQATAQWNEVTMSGYRNASECQRAQYSSYLYNEPGEFRN 624
            :..:|..:...|..||||:|  ::......:.|...::..::|.:||...||:.|..|  ||..|
Zfish   628 FGGIGVVMGHELTHAFDDQGREYDKDGNLRSWWQNSSVEAFKNRTECMVDQYTQYTIN--GEHIN 690

  Fly   625 ATR-LREIIADGSGLNLAFNAYLAWLEQQDHKLRPLLAKETLSELNFTNTQLFFIYFAQTRCWAK 688
            ..: |.|.|||..||..|::||.:|:::...:.|       |..:|.||.||||:.|||..|..:
Zfish   691 GKQTLGENIADNGGLKAAYHAYRSWVQKNGEEKR-------LPAVNLTNDQLFFVGFAQVWCSVR 748

  Fly   689 DNQDAILDSMPLMQHTPERWDVNGPLSNSAEFGREFGCALGTPMNSGDKCLVY 741
            ..:.| .:.:....|:|.::.|.|.||||.||...|.|.||:.||||.:|.|:
Zfish   749 TPESA-HEGLMTDPHSPPKYRVIGTLSNSPEFAEHFQCPLGSSMNSGHRCEVW 800

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl13	NP_651096.1	M13	68..738	CDD:341056	177/751 (24%)
ece2b	XP_073779419.1	None