Protein Alignment Nepl13 and Nep4

DIOPT Version :10

• Sequence 1: NP_651096.1
• Gene: Nepl13 / 42699
• FlyBaseID: FBgn0039022
• Length: 741
• Species: Drosophila melanogaster
• Sequence 2: NP_650904.3
• Gene: Nep4 / 42449
• FlyBaseID: FBgn0038818
• Length: 1040
• Species: Drosophila melanogaster
• Alignment Length: 864
• Identity: 198/864 - (22%)
• Similarity: 337/864 - (39%)
• Gaps: 204/864 - (23%)

  Fly    22 QLCDVTEARQNHMNRMQMSGNFPDSREEQLVRQKIATDVQKYMNLSADPCTDFFEYACGQWGRYH 86
            ::.:.|.|.|:..|.       ..:||.  :|...|..:::||:...|||.||::||||.|.|.|
  Fly   237 EISEATAALQSFWNE-------EGTREG--IRMTQAKTMKRYMDNKVDPCVDFYKYACGNWERLH 292

  Fly    87 KRQLRPDELSTAQQLMET-------------------------------KISEQ----------- 109
            ..........|.:.|.|:                               |::||
  Fly   293 PIPKDKAGFDTFEMLRESLDLVLRNLLEKNTPVHSAAELRKSPVRNTLFKLNEQGEGEGEADQAA 357

  Fly   110 -------------LQQLLTQPL-----------------------------PP------------ 120
                         .:|||.:.|                             ||
  Fly   358 ELTAERLRRHIVSKRQLLNRVLVRYKRYTNGTKRKRLIETPRERTKEEEAAPPVVLPKDKTKDKS 422

  Fly   121 -----QHHPNGYSGASMTNVRKVRAFYESCVAVEANASERRRFLMKILKDNGGLRNVPNSNW-QH 179
                 .|.|..:.........|.:..|.|||.....|......|..::::.||. .|..|.| :.
  Fly   423 DNEEQLHVPTDFLKPHQDAQLKAKNLYRSCVNSAVLAKRGLEPLHTLIRELGGW-PVLESQWSES 486

  Fly   180 NRQWVQTLGELRRNYGLDILLGLEIDLNLQTMKGNTIYFGEPKLTIIPAEHCNALATRGAQVRDE 244
            |..| |.|....|.|..|||:...:..:::..:.|.:.|.:..|.:...|:.       .|..:.
  Fly   487 NFNW-QVLAATLRRYNNDILIVQWVGADIKNSEENIVQFDQTGLGLPTREYF-------LQPSNA 543

  Fly   245 VYELVQQQVTENLRDWFGMDTGEAARFAGDIIRFEFELCKQMGEQDIQKPEEEFPPAIQAQIYGA 309
            .|....|:....:....|....:|.|.|.:::.||.:|.      .|..|.|:
  Fly   544 KYLQAYQRYMAEVMHKMGASKADAQRVASELVAFETQLA------GITAPAEQ------------ 590

  Fly   310 RSRTGQERLRRQKGGMTLTELTSEMGNHLDFKMLVEVILESQY--PSQVYLRSPEYVKHVVRTVK 372
              |....:|.::   |||.:|.:.: ..:.::..::.:.:.:.  ..:|.:.:.||:..:|..:.
  Fly   591 --RLNVTKLYKR---MTLDQLQAVV-PEIKWRAYLQSLQDREVLGTEEVVIYAVEYMSKLVTLLD 649

  Fly   373 ANNRITVGGYILY-----------VALNELNQP-------PEEAPSQRARQCVQVTQRLFPQVLG 419
            ..:..||..|:::           ...:::.|.       .||:| ||.:.|:..........:|
  Fly   650 ETDPRTVSNYMMWRFVRHRINNVDDRFDDIKQSFYHALFGREESP-QRWKVCIAQVNTNMGMAVG 713

  Fly   420 EMFQRHVQRDNAK-------HDLDAVFNDVIKALEEQFHVEWMDENDRRAARTRLS--QYRVSLP 475
            .||......:|:|       |||...|.|::|.      .:|:|:..::.|..:::  ..::..|
  Fly   714 SMFVSRYFDNNSKRDTLRMTHDLQQAFRDILKT------TDWLDDTTKQLAEEKVNAMSLKIGYP 772

  Fly   476 DYQSLDLTDLQFQKS------EDYWRR-LEIALKYRSHQQ---FEALRGNDFGQDADGLDAFEVR 530
            |: .|:.::|..:.:      |.|:.. |.:.|.....:|   .|.:...:: |.|..:    |.
  Fly   773 DF-ILNPSELNSKYAGIEIYPEKYFENTLNVLLHTAKTEQAKLHERVNKTNW-QTAPAI----VN 831

  Fly   531 AALSPRQQMVLVGWGLLQAPYYNYYYPKSLKYALLGHRLASALVQAFDDEG--WNNHPQATAQWN 593
            |..|..:..::...|:||.|:|:.::||||.:..:|..:...|...|||:|  ::.:......|.
  Fly   832 AYYSRNKNQIMFPAGILQPPFYHRHFPKSLNFGGIGVVIGHELTHGFDDKGRLFDRNGNIHKWWT 896

  Fly   594 EVTMSGYRNASECQRAQYSSYLYNEPGEFRNATRLR-EIIADGSGLNLAFNAYLAWLEQQDHKLR 657
            :.::.|:...:.|..||||:|...|.|...|....: |.|||..||..||:||..||::...:
  Fly   897 DSSIRGFDERARCIIAQYSNYTVEEVGIVLNGESTQGENIADNGGLRQAFHAYQRWLKEHPSE-- 959

  Fly   658 PLLAKETLSELNFTNTQLFFIYFAQTRCWAKDNQDAILDSMPLMQHTPERWDVNGPLSNSAEFGR 722
              ::.|.|..||.|..||||:.|.|..|.|. ..:||.:.:....|:|.|:.|.|.||||.:|.|
  Fly   960 --VSDEILPGLNMTGPQLFFLNFGQVWCGAM-RPEAIRNKLNTAIHSPGRFRVIGTLSNSVDFAR 1021

  Fly   723 EFGCALGTPMNSGDKCLVY 741
            ||.|.||:|||...||.|:
  Fly  1022 EFNCPLGSPMNPQKKCSVW 1040

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl13	NP_651096.1	M13	68..738	CDD:341056	185/813 (23%)
Nep4	NP_650904.3	M13	274..1038	CDD:341056	186/814 (23%)