Protein Alignment Nepl13 and Ece2

DIOPT Version :10

• Sequence 1: NP_651096.1
• Gene: Nepl13 / 42699
• FlyBaseID: FBgn0039022
• Length: 741
• Species: Drosophila melanogaster
• Sequence 2: XP_038944493.2
• Gene: Ece2 / 408243
• RGDID: 1303039
• Length: 789
• Species: Rattus norvegicus
• Alignment Length: 680
• Identity: 151/680 - (22%)
• Similarity: 273/680 - (40%)
• Gaps: 125/680 - (18%)

  Fly    55 KIATDVQKYMNLSADPCTDFFEYACGQWGRYHKRQLRPDELSTAQQLMET--KISEQLQQLLTQP 117
            ::|..:.:.::....||.||::::||.|       :|.:.|.:.:....|  .:.:|.|.:|...
  Rat   179 RVAGKILESLDRGVSPCQDFYQFSCGGW-------IRRNPLPSGRSRWNTFNSLWDQNQAILKHL 236

  Fly   118 LPPQHHPNGYSGASMTNVRKVRAFYESCVAVEANASERRRFLMKILKDNGGLRNVPNSNWQHNRQ 182
            |     .|....:|....||.|:||.||:.:|.......:.|..::...||        |.....
  Rat   237 L-----ENSTFNSSSEAERKTRSFYLSCLHLERIEKLGAKPLQDLIDKIGG--------WNITGP 288

  Fly   183 W-----VQTLGELRRNYGLDILLGLEIDLNLQTMKGNTIYFGEPKLTIIPAEHCNALATRGAQVR 242
            |     ::.|..:...|.......:.:..:.::...|.|...:..| .:|:             |
  Rat   289 WDEDNFMEVLKAVAGTYRAAPFFTVYVGADSKSSNSNIIQVDQSGL-FLPS-------------R 339

  Fly   243 DEVYEL---VQQQVTENLRDWF--------GMDTGEAARFAGDIIRFEFELCKQMGEQDIQKPEE 296
            |  |.|   ..::|.....|:.        |..|...|:.. .::..|.:|......||.::.||
  Rat   340 D--YYLNRTANEKVLAAYLDYMVELGMLLGGQPTSTRAQMQ-QVLELEIQLATITVPQDQRRDEE 401

  Fly   297 EFPPAIQAQIYGARSRTGQERLRRQKGGMTLTELTSEMGNHLDFKMLVEVILE-----SQYPSQV 356
                    :||..               |:::||.: :...:|:...:..:|.     ...|..|
  Rat   402 --------KIYHK---------------MSISELQT-LAPSMDWLEFLSFLLSPLELGDSEPVVV 442

  Fly   357 YLRSPEYVKHVVRTVKANNRITVGGYILY----VALNELNQPPEEAPSQ--------------RA 403
            |  ..||::.|...:.......:..|:::    ...:.|:|..|.|..:              |.
  Rat   443 Y--GTEYLQQVSELINRTEPSILNNYLIWNLVQKTTSSLDQRFETAQEKLLETLYGTKKSCTPRW 505

  Fly   404 RQCVQVTQRLFPQVLGEMFQRHVQRDNAKHDLDAVFNDVIKALEEQF-HVEWMDENDRRAARTRL 467
            :.|:..|.......||.:|.:......:|...:.:.:::..|.||.. ::.||||..|.||:.:.
  Rat   506 QTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMISEIRAAFEETLENLVWMDEKTRLAAKEKA 570

  Fly   468 SQY--RVSLPDY--QSLDLTDLQ--FQKSED-YWRRLEIALKYRSHQQFEALRGNDFGQDADGLD 525
            ...  .:..||:  :..:|.|:.  ::.||| :::.:.....:.:....:.|| ....:|...:.
  Rat   571 DAIYDMIGFPDFILEPRELDDVYDGYEVSEDSFFQNMLNLYNFSAKVMADQLR-KPPSRDQWSMT 634

  Fly   526 AFEVRAALSPRQQMVLVGWGLLQAPYYNYYYPKSLKYALLGHRLASALVQAFDDEG--WNNHPQA 588
            ...|.|...|.:..::...|:||||:|.:.:||:|.:..:|..:...|..||||:|  ::.....
  Rat   635 PQTVNAYYLPTKNEIVFPAGILQAPFYAHNHPKALNFGGIGVVMGHELTHAFDDQGREYDQEGNL 699

  Fly   589 TAQWNEVTMSGYRNASECQRAQYSSYLYNEPGEFRNATR-LREIIADGSGLNLAFNAYLAWLEQQ 652
            ...|...:::.::|.:.|...||:.|..|  ||..|..: |.|.|||..||..|:|||.|||.:.
  Rat   700 RPWWQNESLTAFQNHTACMEEQYNQYQVN--GERLNGLQTLGENIADNGGLKAAYNAYKAWLRKH 762

  Fly   653 DHKLRPLLAKETLSELNFTNTQLFFIYFAQ 682
            ..: :||.|      :..||.||||:.|||
  Rat   763 GEE-QPLPA------VGLTNHQLFFVGFAQ 785

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl13	NP_651096.1	M13	68..738	CDD:341056	150/667 (22%)
Ece2	XP_038944493.2	None