Protein Alignment Nepl13 and Nepl10

DIOPT Version :10

• Sequence 1: NP_651096.1
• Gene: Nepl13 / 42699
• FlyBaseID: FBgn0039022
• Length: 741
• Species: Drosophila melanogaster
• Sequence 2: NP_610787.1
• Gene: Nepl10 / 36366
• FlyBaseID: FBgn0033742
• Length: 633
• Species: Drosophila melanogaster
• Alignment Length: 746
• Identity: 147/746 - (19%)
• Similarity: 267/746 - (35%)
• Gaps: 224/746 - (30%)

  Fly    49 EQLVRQKIAT--DVQKYMNLSADPCTDFFEYACGQWGRYHKR----QLRPDELSTAQ-QLMETKI 106
            :.:|...:||  |:...:|.:..|||:|:.:|||::....|.    :...|:.:||. :.||:.:
  Fly    19 QAIVDINVATSNDIHNNLNRTTSPCTNFWNFACGRFSSASKYVDNFERVEDQFATAMVEFMESHL 83

  Fly   107 SEQLQQLLTQPLPPQHHPNGYSGASMTNVRKVRAFYESCVAVEANASERRRFLMKILKDNGGLRN 171
            .|      ...|.|:            .::::|.:|::|                 .:|...|..
  Fly    84 GE------NDTLAPR------------LIKQMRQYYKAC-----------------KEDTRKLHG 113

  Fly   172 VPNSNWQHNRQWVQTLGELRRN----YGLDILLGLEIDLNLQTMKGNTIYFGEPKLTIIPAEHCN 232
            .|......| ||:     |...    |||:   |:.||..:.....:::.:      :|
  Fly   114 NPRPEELVN-QWI-----LHPKKFLVYGLN---GVFIDERVDVAANDSMRW------VI------ 157

  Fly   233 ALATRGAQVR--DEVYELVQQQVTENLR----DWFGMDT---GEAARFAGDIIRFEFELCKQMGE 288
                   |:|  |.......::|.:.:|    .|:.|..   .|......|..|.|:.:......
  Fly   158 -------QLRMPDPADRYSDRRVLQLMRLYEEAWYSMGVVKLVEKMHQLQDKYRAEYPVVYTWSF 215

  Fly   289 QDIQKPEEEFPPAIQAQIYGARSRTGQERLRRQKGGMTLTELTSEMGNHLDFKML-VEVILE--- 349
            .:::: |...|.:...::.|...                   |.|: .||.|::. ||.:.|
  Fly   216 SELRQ-EIPIPHSFFIELLGVNH-------------------TEEL-YHLTFEVSDVEYLRECFR 259

  Fly   350 -----SQYPSQVYLRSPEYVKHVVRTVKANNRITVGGYILYVALNELNQPPEEAPSQRARQCVQV 409
                 :..|...|:|:.:||                       |.|.::|.|..|    |.|:..
  Fly   260 CLRDFASEPKDTYIRARQYV-----------------------LVEESEPRERNP----RSCIHH 297

  Fly   410 TQRLFPQVLGEMFQRHVQRDNAKHDLDAVFNDVIKALEEQFHVEWMDENDRRAARTRLSQYRVSL 474
            .:...|..:..::.|.:.: |.:.|...|. :::..|:..|. :::|.|..:....:|:..|..|
  Fly   298 MRAYLPLGMNYIYDRFIYQ-NREEDTSKVL-EILSTLKAAFG-QYLDANRLQLTPNQLAYVRAKL 359

  Fly   475 PDYQSLDLTDLQFQKSEDYWRRLEIALKYRSHQQFEALRGNDFGQDADGLDAFEVRAAL------ 533
            ...| :.:.:|..:||.::         |.:|.........:|  .|:.|:||.:|..|
  Fly   360 EGIQ-IKIGNLPEEKSPEF---------YNNHYGSANFSATNF--LANLLEAFALRTRLQNAGLL 412

  Fly   534 ----------------------SP----RQQMVLVGWGLLQAPYYNYYYPKSLKYALLGHRLASA 572
                                  ||    .:..:.|....||.|.:::......:::|||..|...
  Fly   413 ARNSRVDLRHYYVNDNVRKARTSPFYENERNTITVPMEFLQWPLFDHREHTIFQHSLLGAVLGHE 477

  Fly   573 LVQAFDDEG------WNNHPQATAQWNEVTMS-GYRNASECQRAQYSSYLYNEPGEFRNATRLRE 630
            :..||:.||      .|..|...    |:..| .:|:|.:|             .|.:....|:|
  Fly   478 MNHAFEQEGILFDAAGNESPVGL----EIRESKPFRDAIKC-------------AEEQPFVSLKE 525

  Fly   631 IIADGSGLNLAFNAYLAWLEQQDHKLRPLLAKETLSELNFTNTQLFFIYFAQTRCWAKDNQDAIL 695
            .:||.:||.||::|:....    |..|....:....|..||..|||.:.:||..|.:..
  Fly   526 RLADLNGLQLAYDAFFGLA----HDSRQFEYRPYAFEQEFTAPQLFHLSYAQFFCGSLP------ 580

  Fly   696 DSMPLMQHTPERWDVNGPLSNSAEFGREFGC 726
               |::.|..:...||..:.|..:|..:|.|
  Fly   581 ---PVIAHDRDDERVNVSVGNLRQFAYDFNC 608

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl13	NP_651096.1	M13	68..738	CDD:341056	142/725 (20%)
Nepl10	NP_610787.1	GluZincin	41..608	CDD:472708	141/722 (20%)