Protein Alignment Nepl13 and Nepl8

DIOPT Version :10

• Sequence 1: NP_651096.1
• Gene: Nepl13 / 42699
• FlyBaseID: FBgn0039022
• Length: 741
• Species: Drosophila melanogaster
• Sequence 2: NP_609795.2
• Gene: Nepl8 / 34983
• FlyBaseID: FBgn0032585
• Length: 619
• Species: Drosophila melanogaster
• Alignment Length: 747
• Identity: 156/747 - (20%)
• Similarity: 289/747 - (38%)
• Gaps: 211/747 - (28%)

  Fly    55 KIATDVQKYMNLSADPCTDFFEYACGQWGRYHKRQLRPDELSTAQQLMETKISEQLQQLLTQPLP 119
            ::...:..:::..|:||.:::.:||||   |:.|.: .|......|:::.::::.|.:|:.:...
  Fly    19 RLLNGILSHVDKEANPCENYYNHACGQ---YNMRHI-DDTFFDIIQMLDHQVNQNLVKLMDELEM 79

  Fly   120 PQHHPNGYSGASMTNVRKVRAFYESCVAVEANASERRRFLMKILKDNGGL---RNVPN-SNW-QH 179
            ....|: ::.:|:..  ||..:|.||.....|.....::| |::....||   :.:|: |:| |.
  Fly    80 SSQLPD-FNVSSVDG--KVLRYYLSCRGAPRNMDSLSQYL-KVISPGEGLTWPQFIPDGSSWPQE 140

  Fly   180 NRQWVQTLGELRRNYGL-DILLGLEIDLNLQT-----MKGNTIYFGEPK---------LTI---- 225
            |.:|::.|..|.| ||| ::...||:..|.:.     ::.||..|||..         |::
  Fly   141 NFKWLKALAHLHR-YGLTNVFFNLEVVSNPRNASEYMVELNTPTFGEESQLPNSFIEILSVLYII 204

  Fly   226 -IPAEHCNALATRGAQVRDEVYELVQQQVTEN-----LRDWFGMDTGEA-ARFAGDII------- 276
             :|:.....||.:...:...:..::....|.|     :|| |.|:||.. .||...:|
  Fly   205 KVPSSEIITLARKMRTLELLLKTMINPIDTLNNRYISIRD-FQMETGHNWQRFFEILIGSSAAPE 268

  Fly   277 --------RFEFELCKQMGEQDIQKPEEEFPPAIQAQIYGA--RSRTGQERLRRQKGGMTLTELT 331
                    |:...|.:.|.:||             |::..:  .:|.....|....||...||..
  Fly   269 LQVLVRNFRYFTALKELMDKQD-------------ARLVASYIMTRFAIFLLDETMGGRESTECV 320

  Fly   332 SEMGNHLDF--KMLVEVILESQYPSQVYLRSPEYVKHVVRTVKANNRITVGGYILYVALNELNQP 394
            |::..:::.  .||        |..:.:..|         |..||        ||.:.
  Fly   321 SQVRRNMNLAANML--------YKERFFEDS---------TFSAN--------ILEIK------- 353

  Fly   395 PEEAPSQRARQCVQVTQRLFPQVLGEMFQRHVQRDNAKHDLDAVFNDVIKALEEQFHVEWMDEND 459
                         .:.::|..|.|.::.|.|::               :.||:.:|.|
  Fly   354 -------------DIFEKLRHQFLLQVDQNHLE---------------LTALQMKFFV------- 383

  Fly   460 RRAARTRLSQYRVSLPDYQSLD------LTDLQFQKSE-DYWRRLEIALKYRSHQQF-EALRGND 516
            |:|....::.  |:||....|.      ..||||...| ||.:.....|::|:.:.. ::.:|:
  Fly   384 RKAEAIEINV--VNLPKTDDLRHFIGQYYQDLQFPTGELDYHQEHLKVLQFRTQKMLAQSSKGH- 445

  Fly   517 FGQDADGLDAFEVRAALSPRQQMVLVGWGLLQAPYYNYYYPKSLKYALLGHRLASALVQAFDDEG 581
              .:...:..:..:||..|..|           |::........||:|:|:.:|..|:.||..||
  Fly   446 --SEEQNILTYRSQAAPLPPPQ-----------PFFQLESEDVFKYSLMGYIMAHHLISAFATEG 497

  Fly   582 WNNHPQATAQWNEVTMSGYRNASECQRAQYSSYLYNEPGE--FRNATRLREIIADGSGLNLAFNA 644
                         :|:     .|:.....:.|:.:.|...  .||:..:.|.:.|.:||.||:..
  Fly   498 -------------ITI-----GSDGNDQSFRSHRFEEAVSCLSRNSENIDESMGDIAGLELAYFT 544

  Fly   645 YLAWLEQQDHKLRPLLAKETLSELNFTN---TQLFFIYFAQTRCWAKDNQDAILDSMPLMQHTPE 706
            |..            :||.. :.|:||:   .|:||:...|..|   .|.|.      |:|:..:
  Fly   545 YAK------------MAKNR-NRLDFTHLPPEQIFFLNVGQFFC---GNSDM------LVQYKED 587

  Fly   707 RWDVNGPLSNSAEFGREFGCALGTPMNSGDKC 738
            :..:...:.....|.:.|||....|.:  :||
  Fly   588 QVRLQRAIEGFEPFDKAFGCYRNKPKH--EKC 617

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl13	NP_651096.1	M13	68..738	CDD:341056	154/732 (21%)
Nepl8	NP_609795.2	GluZincin	32..618	CDD:472708	156/734 (21%)