Protein Alignment Nepl13 and Nepl4

DIOPT Version :10

• Sequence 1: NP_651096.1
• Gene: Nepl13 / 42699
• FlyBaseID: FBgn0039022
• Length: 741
• Species: Drosophila melanogaster
• Sequence 2: NP_609019.1
• Gene: Nepl4 / 33889
• FlyBaseID: FBgn0031805
• Length: 652
• Species: Drosophila melanogaster
• Alignment Length: 768
• Identity: 165/768 - (21%)
• Similarity: 280/768 - (36%)
• Gaps: 241/768 - (31%)

  Fly    52 VRQKIATDVQKYMNLSADPCTDFFEYACGQWGRYHKRQLRPDELSTAQQLMETKISEQLQ----Q 112
            :.|:....:..|::...:||.||:.||||:|...|...      :||..:.|::|:.|.:    |
  Fly    42 INQQHIDTLMSYVDSEKNPCEDFYAYACGKWRAKHGSH------TTATMISESQINRQYEDLFLQ 100

  Fly   113 LLTQPLPPQHHPNGYSGASMTNVRKVRAFYESCVAVEANASERRRFLMKILKDNGGLRNVPNSNW 177
            ||..|..|::   ||     ....||.|.|:||:|:|  ..:.||::.  |.|...|.::.:::|
  Fly   101 LLRNPSAPEY---GY-----PMFAKVLAHYQSCIALE--KPDLRRYIE--LLDRDLLASLNSTHW 153

  Fly   178 QHNRQWVQTLGELRRNYGLDILLG--LEIDLNLQTMKGNTIYFGEPKLTIIP-AEHCNALATRGA 239
            .|      .|..|.| ||..   |  :::::.......:.|:       ::| ..|.|...|:
  Fly   154 MH------LLAALGR-YGYH---GHYVQVEVRWYNATHHMIF-------LLPHNRHLNLSLTQ-- 199

  Fly   240 QVRDEVYELVQQ---------QVTENLRDWFGMDTGEAARFAGDIIRFEFELCKQMGEQDIQKP- 294
                ::|:.:.|         |:.|..|.           ...:::|             :.||
  Fly   200 ----DIYDALSQDGSSWPPLHQLQEQFRS-----------LEQNLVR-------------LAKPH 236

  Fly   295 --EEEFP----PAIQAQIYGARSRTGQERLRRQKGGMTLTELTSEMGNH---LDFKMLVEVILES 350
              ::.|.    ..|:.::.|..   ..|.||.|.|       .|..|||   :|....:|.::|
  Fly   237 SADDTFRNYSLDQIRTEVPGLH---WDEALRTQLG-------RSVPGNHVFQVDDLDAIEGLVE- 290

  Fly   351 QYPSQVYLRSPEYVKHVVRTVKANNRITVGGYILYVALNELNQPP----EEAPSQRARQCVQ--- 408
                  ||       :.|.|:.. ||.::..::.:  |.||...|    |.....|.|.|::
  Fly   291 ------YL-------NTVDTLLL-NRYSLARFLSH--LLELPHNPLATWESGQRSRGRNCIRHMR 339

  Fly   409 ---------VTQRLF--------PQVLGEMFQRHVQRD---NAKHDLDAVFNDVIKALE------ 447
                     |.:|.|        ..|:..:||: :|..   ..:|:...:..|::|:|:
  Fly   340 RSVYLPMNYVYERSFYSRRRHADELVIHSVFQQ-LQSQLELRVQHNAFNLSQDLVKSLQAKVHQM 403

  Fly   448 ------------EQFHVEWMDENDRR--AARTRLSQYRVSLPDYQSL--DLTDLQFQKSEDYWRR 496
                        |||:  |  ::|||  ..|.....:..||..|.:|  ||.....|:..|.|
  Fly   404 RINVGNLPPNVTEQFY--W--DSDRRWSVGRDFYENHLNSLLYYYTLVADLESSSDQEERDIW-- 462

  Fly   497 LEIALKYRSHQQFEALRGNDFGQDADGLDAFEVRAALSPRQQMVLVGWGLLQAPYYNYYYPKSLK 561
                ..:..|..          :..|.:||......|.   .::.|.:..::.|:::..:..:|.
  Fly   463 ----YSFNMHTP----------EFPDNIDATPYFYCLG---NIIFVPYSYVKRPFFDANFWPALL 510

  Fly   562 YALLGHRLASALVQAFDD-----EGWNNHPQATAQWNEVTMSGYRNASECQRAQYSSYLYNEPGE 621
            |..|.:.|...::.|||.     :...|....:.|..||.:  |..|..|..:
  Fly   511 YGDLANTLGHEIMHAFDTDLVDYDAQGNLRNFSDQLGEVEL--YNGAVGCLNS------------ 561

  Fly   622 FRNATRLREIIADGSGLNLAFNAYLA-WLEQQDHKLRPLLAKETLSELNFTNTQLFFIYFAQTRC 685
              :|..|.|..:|.||..||...|.. ||.:..                  |.:|:|:.||...|
  Fly   562 --SAVMLNERTSDVSGSRLAMQTYGGDWLTRSG------------------NGRLYFLQFAHFFC 606

  Fly   686 WAKDNQDAILDSMPLMQHTPERWDVNGPLSNSAEFGREFGCALGTPMNSGDKC 738
            ..:.:|          .|......:|..|....:|...|.|.:|:.|.|.|:|
  Fly   607 GDEGDQ----------YHDSGSQRLNYALGQVPQFAEVFRCHVGSGMTSADQC 649

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl13	NP_651096.1	M13	68..738	CDD:341056	162/750 (22%)
Nepl4	NP_609019.1	GluZincin	59..649	CDD:472708	162/749 (22%)