Protein Alignment Nepl13 and goe

DIOPT Version :9

• Sequence 1: NP_651096.1
• Gene: Nepl13 / 42699
• FlyBaseID: FBgn0039022
• Length: 741
• Species: Drosophila melanogaster
• Sequence 2: NP_001285350.1
• Gene: goe / 32660
• FlyBaseID: FBgn0027528
• Length: 879
• Species: Drosophila melanogaster
• Alignment Length: 746
• Identity: 143/746 - (19%)
• Similarity: 261/746 - (34%)
• Gaps: 220/746 - (29%)

  Fly    63 YMNLSADPCTDFFEYACGQWGRYH--------KR-QLRPDELSTAQQLMETKISEQLQQLLTQPL 118
            :.|.|..||.:.:|:|||.:...:        || :...:..:..|:|.|  ::..:..|
  Fly   178 WANTSKSPCHETYEWACGNFASDYANHEYFVIKRGEWNYETYNEYQELNE--LNRFIAML----- 235

  Fly   119 PPQHHPNGYSGASMTNVRKVRAFYESCVAVEANASERRRFLMK----------ILKDNGGLRNVP 173
                 ||...|:..:.   |.:.|.||...:.....:...|:|          ..:|:..|:
  Fly   236 -----PNSQEGSVEST---VSSLYRSCRETDVLDKSQSDLLLKRAINAVYGWQAFRDSNRLQ--- 289

  Fly   174 NSNWQHNRQWVQTLGELRRNYGLDILLGLEIDLNLQTMKGNTIYFGEPKLTIIPAEHCNALATRG 238
              :|::.|    .|..|:..:|:.....:.::..........|...|.:|. :|.::     ..|
  Fly   290 --SWEYKR----VLVVLQAKHGIFPYYRVTVENGFSNPHDYVITLDEGELG-LPDKY-----FYG 342

  Fly   239 AQVRDEV---YELVQQQVTENLRDW---FGMDTGEAARFAGDIIRFEFELCK------------- 284
            ....:||   |:|:       |||:   .|:.:.||..||.||..:|..:..
  Fly   343 NDADEEVVRGYKLL-------LRDFAINMGIVSREADLFADDIFHYERRIVNHIEDAKADANRPI 400

  Fly   285 ----QMGEQDIQKPEEEFPPAIQAQIYGARSRTGQERLRRQK------------------GGMTL 327
                ::.:..|:.|......::||.....:.....|.|.|..                  ....:
  Fly   401 NKLMRLADLKIKAPSLPILESLQAIFPKTKITEDTEVLVRDPEVMHALSVLLSTSDKKPINNFIV 465

  Fly   328 TELTSEMGNHL--DFKMLVEVILESQYPSQVYLRSPEYVKHVVRTVKANNRITVGGYILYVALNE 390
            ..|..:|..||  :::.|.|.     :...:|.|:..|.:.::.:....:       .|..|::.
  Fly   466 WSLARKMLPHLSKEYRTLAET-----FDHALYGRTASYPRWLICSKVVRD-------WLPFAVDA 518

  Fly   391 LNQPPEEAPSQRARQCVQVTQRLFPQVLGEMFQRHVQRDNAKHDL-----DAVFNDVIKALEEQF 450
            |.|.|   |.|   |...:|.:          .|.:.:.....:|     .::.|.:..:||:
  Fly   519 LQQQP---PRQ---QFETMTSK----------SRGLNKTQGNEELLKLMFFSLRNQLKDSLEQ-- 565

  Fly   451 HVEWMDENDRRAARTRLSQYRV--SLPD------------YQSLDLTDLQF-QKSEDYW--RRLE 498
             .:|::...|:..:.:|::.|:  .:||            |..|.|.::.| :..|..|  ||.:
  Fly   566 -AKWLEPAARQFIQKKLNEMRLQFGIPDEVLQQPTYLAQYYNELILNNVFFVEHLEWIWTFRRSQ 629

  Fly   499 IALKYRSHQQFEALRGNDFGQDADGLDAFEVRAALSPRQQMVLVGWGLLQAPYYNYYYPKSLKYA 563
            :..|.......:.:....:.:|.....|:      |.:..|:||...|:.:.||:|.||.::.:|
  Fly   630 MEKKLGPLAILDVIVSEMYTRDNPQAIAY------SNKLNMLLVSKVLISSNYYDYRYPVAVNFA 688

  Fly   564 LLGHRLASALVQAFDD--EGWNNH--------------------------PQATAQWNE------ 594
            .:|..:..||:..|..  ..:|..                          |:...:.||
  Fly   689 RIGTDILEALIDNFSTFLLQFNTQSTDISDAAPEIRYAQPDVNCLAAGQPPRLVHELNELSSNAL 753

  Fly   595 ----VTMSGYRNASECQRAQYSSYLYNEPGEFRNATRLREIIADGSGLNLAFNAYLAWLEQQDHK 655
                ||:|..|.|:..        |.|    |.||......| .|||::.| |.|.|.  ....:
  Fly   754 KSFHVTLSAARTAARA--------LSN----FVNAIDAGSAI-QGSGIDQA-NTYEAL--GLTRR 802

  Fly   656 LR-PLLAKETLSELNFTNTQLFFIYFAQTRC 685
            || |.|.       :|...:||.:.:.|..|
  Fly   803 LRIPGLR-------SFNENELFTLSYMQQHC 826

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl13	NP_651096.1	PepO	63..732	CDD:226118	143/746 (19%)
		M13	68..738	CDD:189000	141/741 (19%)
goe	NP_001285350.1	GluZincin	184..>694	CDD:301352	107/583 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45469672
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840