Protein Alignment Nepl13 and Nep1

DIOPT Version :10

• Sequence 1: NP_651096.1
• Gene: Nepl13 / 42699
• FlyBaseID: FBgn0039022
• Length: 741
• Species: Drosophila melanogaster
• Sequence 2: NP_511056.2
• Gene: Nep1 / 31547
• FlyBaseID: FBgn0029843
• Length: 849
• Species: Drosophila melanogaster
• Alignment Length: 774
• Identity: 193/774 - (24%)
• Similarity: 320/774 - (41%)
• Gaps: 154/774 - (19%)

  Fly    38 QMSGNFPDSREEQLVRQ---KIATDVQKYMNLSADPCTDFFEYACGQWGRYHKRQLRPDELSTAQ 99
            |.||:..:.::...:.|   :.|..:...|:|::|||.|||:||||.|.:.|........:||.:
  Fly   160 QDSGSAHEGQDNICMTQECVRTAASLLSAMDLNSDPCEDFFQYACGTWNKMHPIPEDRSSISTFE 224

  Fly   100 QLMETKISEQ----LQQLLTQPLPPQHHPNGYSGASMTNVRKVRAFYESCVAVEANASERRRFLM 160
            .|     |:|    |:.:|.:|:..:.:.     |::    |.:.|::||:.:..........|.
  Fly   225 VL-----SDQQQVILRAVLEEPIDERDNK-----ATI----KAKTFFKSCMDIPQIRKIGTGRLK 275

  Fly   161 KILKDNGGLRNVPNSNWQ--HNRQWVQTLGELRRNYGLDILLGLEIDLNLQTMKGNTIYFGEPKL 223
            ::|:..||. .|...||.  .:....:.:|:||.||...:::.|.:..:.:....|.:...:.:.
  Fly   276 QVLQSLGGW-PVIERNWSPPADLSVERLMGQLRLNYSEPVMIELYVGADDKNSSVNILQMDQLQY 339

  Fly   224 TIIPAEHCNALATRGAQVRD------EVYELVQQQVTENLRDWFGMDTGEAARFAGDIIRFEFEL 282
                     ||.:|...:::      ..|.....||...|    |.|...||.....::.||.:|
  Fly   340 ---------ALPSRDYYLKESSANDRRAYHRYMTQVALLL----GADPATAAAELEKVVLFETQL 391

  Fly   283 CK-QMGEQD----------IQKPE-EEFPPAIQAQIYGARSRTGQERLRRQKG-GMTLTE----- 329
            .. .:.|.|          :..|| :|..|.:|          .||.|:...| |:.|.|
  Fly   392 VNVSLPEADRHDTSLVYRKMLLPELQELVPEVQ----------WQEYLQAALGPGIPLQEDEPLV 446

  Fly   330 -----LTSEMGN---HLDFKMLVEVILESQYPSQVYLRSPEYVKHVVRTVKANNRITVGGYILYV 386
                 ..:|||.   |.|.:::...:|.....|.:.....||.:..|..    .:|.:|
  Fly   447 TYGLHYLTEMGKILAHTDRRVVHNYMLWRLVMSLMSHMIDEYQRERVEF----RKILMG------ 501

  Fly   387 ALNELNQPPEEAPSQRAR--QCVQVTQRLFPQVLGEMFQRHVQRDNAK-------HDLDAVFNDV 442
                       ..|:|.|  |||:.|.:.....:|.:|.|......:|       |.:.|.||::
  Fly   502 -----------IQSERTRWSQCVEWTNKKLGVAVGALFIRDNFNQESKEVALEMIHTIRAAFNEL 555

  Fly   443 IKALEEQFHVEWMDENDRRAARTRLSQY--RVSLPDYQSLDLTDLQFQ------KSEDYWRRLEI 499
               |.|.   :|||:..|..|:.:....  |:..|:..: :.|:|:.:      ..:::...:..
  Fly   556 ---LAEN---DWMDDETRAVAKEKADSMNERIGYPELLT-NATELEQEYVNLTIVPDNFINNVLS 613

  Fly   500 ALKYRSHQQFEALRGNDFGQDAD----GLDAFEVRAALSPRQQMVLVGWGLLQAPYYNYYYPKSL 560
            .|::.|.:....||     |..|    ..:...|.|..:|.:..::...|:||..:|:.::||||
  Fly   614 ILQWESEKMLRLLR-----QPVDKEKWTTEPAVVNAFYNPNKNDIVFPAGILQPLFYSQHFPKSL 673

  Fly   561 KYALLGHRLASALVQAFDDEG--WNNHPQATAQWNEVTMSGYRNASECQRAQYSSYLYNEPGEFR 623
            .|..:|..:...:...|||:|  ::........||..|:..:|..::|...|||.|..||...|.
  Fly   674 NYGGIGVVIGHEITHGFDDKGRQFDKEGNMMQWWNNATIEAFRERTQCVIDQYSRYKINEVDMFM 738

  Fly   624 NATRLR-EIIADGSGLNLAFNAYLAW-----LEQQDHKLRPLLAKETLSELNFTNTQLFFIYFAQ 682
            :....: |.|||..||..||.||..|     .|||            |..||.|:.||||:.:||
  Fly   739 DGRMTQGENIADNGGLKQAFRAYKKWETLHGREQQ------------LPGLNMTHDQLFFLNYAQ 791

  Fly   683 TRCWAKDNQDAILDSMPLMQHTPERWDVNGPLSNSAEFGREFGCALGTPMNSGDKCLVY 741
            ..|.:...:|| |..:....|:|....|.||||||.:|...:.|.||:.||..:||.|:
  Fly   792 IWCGSMRPEDA-LTKIRSAVHSPGFVRVLGPLSNSRDFASAYKCPLGSTMNPAEKCSVW 849

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl13	NP_651096.1	M13	68..738	CDD:341056	183/736 (25%)
Nep1	NP_511056.2	M13	194..847	CDD:341056	184/736 (25%)