Protein Alignment Nepl13 and Kel

DIOPT Version :9

• Sequence 1: NP_651096.1
• Gene: Nepl13 / 42699
• FlyBaseID: FBgn0039022
• Length: 741
• Species: Drosophila melanogaster
• Sequence 2: NP_115929.3
• Gene: Kel / 23925
• MGIID: 1346053
• Length: 713
• Species: Mus musculus
• Alignment Length: 758
• Identity: 166/758 - (21%)
• Similarity: 287/758 - (37%)
• Gaps: 200/758 - (26%)

  Fly    65 NLSADPCTDFFEYACGQWGRYHKRQLRPDELSTAQQLMETKISEQLQQLLTQPLPPQHHPNGYSG 129
            |.|..||||||.:||.          :.:..|.:.|.:..:...:|.:||..| ...|..:|
Mouse    75 NRSVAPCTDFFSFACE----------KANGTSDSFQALTEENKSRLWRLLEAP-GSWHLGSG--- 125

  Fly   130 ASMTNVRKVRAFYESCV---AVEANASERRRFLMKILKDNGGLRNVPNSNWQHNRQWVQTLGELR 191
                 ..|...||.||:   |:||:.|..   |::|:::.||        |.....|.
Mouse   126 -----EEKAFQFYNSCMDTDAIEASGSGP---LIQIIEELGG--------WNITGNWT------- 167

  Fly   192 RNYGLDILLGLEIDLNLQTMKGNTIYFGEPKLTIIPAEHCNALATRGAQVRDEVYELVQQQVTEN 256
                     .|:.:.||:.:.....:|  |........|.....|...|:....::::.||..|.
Mouse   168 ---------SLDFNQNLRLLMSQYGHF--PFFRAYLRPHPAPPHTPIIQIDQPEFDILLQQEQEQ 221

  Fly   257 ------LRDW----------FGMDTGEAARFAGDIIRFEFELCKQMGEQDIQKPEEEFPPAIQAQ 305
                  ||::          .|.:..||.:.|...|.|...|.:.:..|..|:.:::....:
Mouse   222 KVYAQILREYVTYLNRLGTLLGSNPQEAQQHASWSIVFTSRLFQFLRPQQQQQAQDKLFHVV--- 283

  Fly   306 IYGARSRTGQERLRRQKGGMTLTELTSEMGNHLDFKMLVEVILE--SQYPSQ-VYLRSPEYVKHV 367
                                |:.|| .||...:|:...::.|..  |...|| :.:...:|::::
Mouse   284 --------------------TIDEL-QEMAPAIDWLSCLQAIFTPMSLNSSQTLVVHDLDYLRNM 327

  Fly   368 VRTVK---ANNRITVGGYILYVALNELNQPPEEAPSQRAR-----------------------QC 406
            .:.|:   .|:|.::..|::...::.|: |..:...|.||                       :|
Mouse   328 SQLVEEGLLNHRESIQSYMILGLVDTLS-PALDTKFQEARRELIQELRKLKERPPLPAYPRWMKC 391

  Fly   407 VQVTQRLFPQVLGEMFQRHV---QRDNAKHDLDAVFND-VIKALEEQFHVEWMDENDRRAARTRL 467
            |:.|...|...|..:|.|..   ...:|..:|.|...| ||..|::   :.|:.|..::.|..:|
Mouse   392 VEQTGAFFEPTLAALFVREAFGPSIQSAAMELFAEIKDAVIIRLKK---LSWISEETQKEALNKL 453

  Fly   468 SQYRVSL--------PDYQSLDLTDLQFQKS--EDYWRRLEIALKYRSHQQFEALRGNDFGQDAD 522
            :|.:|.:        ||..:.:..|:|...|  :.:...:. :|:.|:.|.|
Mouse   454 AQLQVEMGAPKRAVKPDIATQEYNDIQLGPSFLQSFLSCVR-SLRARNVQSF------------- 504

  Fly   523 GLDAF----------EVRAALSPRQQMVLVGWGLLQAPYYNYYYPKSLKYALLGHRLASALVQAF 577
             |..|          ||.|..|....||:...||||.|:::..||:::.:...|..:|..|:..|
Mouse   505 -LQPFPYHRWQKSPWEVNAYYSISDHMVVFPAGLLQPPFFHPGYPRAVNFGAAGSIMAHELLHIF 568

  Fly   578 DDEGWNNHPQATAQWNEVTMSG---------YRNASECQRAQYSSYLYNEPGEFRNATRLREIIA 633
                           .::.:.|         .:.|..|....|:::.......|..:..|.|..|
Mouse   569 ---------------YQLLLPGGCPACDTHVLQEALLCLERHYAAFPLPSISSFNGSHTLLENAA 618

  Fly   634 DGSGLNLAFNAYLAWLEQQDHKLRPLLAKETLSELNFTNTQLFFIYFAQTRCWAKDNQDAILDSM 698
            |..|:.:||.||...:.:...:|       ||..|:.:..||||..:||..|....:||
Mouse   619 DIGGVAIAFQAYSKRIVEHTGEL-------TLPNLDLSPYQLFFRSYAQVMCRGLSSQD------ 670

  Fly   699 PLMQHTPERWDVNGPLSNSAEFGREFGCALGTPMNSGDKCLVY 741
            |...|:|....|:|||||:.:|.:.|.|..||.:|...:|.::
Mouse   671 PQDPHSPPSLRVHGPLSNTPDFAKHFHCPRGTLLNPSARCKLW 713

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl13	NP_651096.1	PepO	63..732	CDD:226118	164/747 (22%)
		M13	68..738	CDD:189000	163/750 (22%)
Kel	NP_115929.3	M13	78..711	CDD:341056	163/751 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167841062
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	7	6.810