Protein Alignment Nepl13 and nep-24

DIOPT Version :9

• Sequence 1: NP_651096.1
• Gene: Nepl13 / 42699
• FlyBaseID: FBgn0039022
• Length: 741
• Species: Drosophila melanogaster
• Sequence 2: NP_503005.3
• Gene: nep-24 / 190993
• WormBaseID: WBGene00013786
• Length: 567
• Species: Caenorhabditis elegans
• Alignment Length: 662
• Identity: 121/662 - (18%)
• Similarity: 215/662 - (32%)
• Gaps: 177/662 - (26%)

  Fly    10 GFLLELLLLFEIQLC--DVTEARQNHMNRMQMSGNFPDSREEQLVRQKIATDVQKYMNLSADPCT 72
            ||:|.|||.....|.  ..|.|.:|..|.....              .:|..:..|.:.|.|||.
 Worm    12 GFMLLLLLTCTAPLAIGATTPATRNVCNTPACI--------------TLAHMLHNYHDPSVDPCD 62

  Fly    73 DFFEYACGQWGRYHKRQLRPDELSTAQQLMETKISEQLQQLLTQPLPPQHHPNGYSGASMTNVRK 137
            :|.::|||:...:....:...:..|...:|:..:.:                |..|.:...|.
 Worm    63 NFHQFACGREHEHETEDIYTKKTKTINNIMKRFLKK----------------NETSRSKSENA-- 109

  Fly   138 VRAFYESCVAVEANA-SERRRFLMKILKD--NGGLRNVPNSNWQHNR----QWVQTLGEL-RRNY 194
            :|..|::|..:|.|: :.|.:.|..|.:|  :.|...|.:..|..::    .::..|..| |:|:
 Worm   110 MRTLYKACKTLEKNSTASRNKALQDIFQDIQSIGAWPVVDDKWDESKFDLNDFLVNLVRLGRKNF 174

  Fly   195 GL----------DILLGLE------IDLN---LQTMKGNTIYFGEPKLTIIPAEHCN---ALATR 237
            ||          :..:|.|      :||.   .:.:|.|::.....||....||:.|   ||:
 Worm   175 GLFQMARYVNVRNFAIGPEAAWRHNVDLGKTISEILKANSVQTNNKKLLDDLAEYVNLEKALS-- 237

  Fly   238 GAQVRDEVYELVQQQVTENLRDWFGMDTGEAARFAGDIIRFEFELCKQMGEQDIQKPEEE--FPP 300
                 ...:..||.          |....|.:.|...:......|       ::..|::.  ||
 Worm   238 -----QHKFNTVQP----------GYIFSERSDFVSSVNFSRLVL-------EMMSPDKRTLFP- 279

  Fly   301 AIQAQIYGARSRTGQERLRRQKGGM-TLTELTSE--MGNHLDFKMLVEVILESQYPSQVYLRSPE 362
                ::|.....|.......:...: |:...||:  :.|:|.||.:...|.:..|.|
 Worm   280 ----EVYQIMYLTNTSLFFGKNNNLETIIRNTSKRALANYLIFKFIDTSIADLTYGS-------- 332

  Fly   363 YVKHVVRTVKANNRITVGGYILYVALNELNQPPEEAPSQRARQCVQVTQRLFPQVLGEMFQRH-V 426
                                                ||   ..|.|......|:.....|.|: :
 Worm   333 ------------------------------------PS---AFCEQKVINFLPRAALRAFYRNFI 358

  Fly   427 QRDNAKHDLDAVFNDVIKALEEQFHVEWMDENDRRAARTRLSQYR--VSLPDY----QSLD--LT 483
            .::|.|..........::.|:.....:||....::.|..|:|...  :..|||    ..||  ..
 Worm   359 SKENRKKITKLTEATQVQLLKIIGATDWMSIKSKKIAMDRVSSMNMVIGYPDYFDPPGKLDGLFE 423

  Fly   484 DLQFQKSEDYWRRLEIALKYRSHQQFEALRGN-DFGQDADGLDAFEVRAALSPRQQMVLVGWGLL 547
            .|....|:.|:..:....::...|:.:...|. .:.....||   ...|..:.....:::.....
 Worm   424 HLNLSSSDTYYTVVRKINRFMREQEMDYYTGEVPYYPLFPGL---MTNAMYNANDNNLMIFAPFF 485

  Fly   548 QAPYYNYYYPKSLKYALLGHRLASALVQAFD----------DEGWNNHPQATAQWNEVTMSGYRN 602
            ..|:::..:|.....|...:.||..:...|.          .|.|.. |:.|.:        |..
 Worm   486 DDPFFDSSFPDYANIAFTSNTLAHEMGHTFSPHLMDIMTGTTEVWLT-PKETEE--------YEK 541

  Fly   603 ASECQRAQYSSY 614
            ..:|...||:.|
 Worm   542 RVKCLEDQYTEY 553

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl13	NP_651096.1	PepO	63..732	CDD:226118	109/607 (18%)
		M13	68..738	CDD:189000	107/602 (18%)
nep-24	NP_503005.3	GluZincin	58..561	CDD:301352	107/602 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920