Protein Alignment Nepl13 and nep-20

DIOPT Version :9

• Sequence 1: NP_651096.1
• Gene: Nepl13 / 42699
• FlyBaseID: FBgn0039022
• Length: 741
• Species: Drosophila melanogaster
• Sequence 2: NP_001317749.1
• Gene: nep-20 / 188176
• WormBaseID: WBGene00020293
• Length: 834
• Species: Caenorhabditis elegans
• Alignment Length: 756
• Identity: 137/756 - (18%)
• Similarity: 266/756 - (35%)
• Gaps: 214/756 - (28%)

  Fly    56 IATDVQKYMNLSADPCTDFFEYACGQWGRYHKRQLRPDELSTAQQLMETKISEQL---QQLLTQP 117
            :|.::..|.:.|...|.:|::..||::  .|.:.|.....:..:::::..:.|.|   :..:|..
 Worm   223 LAFELSAYQDTSVSKCHNFYKATCGKY--KHHQALDKHRDAKKKEVVKRIVREFLRRNESSITSK 285

  Fly   118 LPPQHHPNGYSGASMTNVRKVRAFYESCVAVEANASERRRFLMKILKDNGGLRNVPNSNWQHNRQ 182
            ..|                .:|..:..|     |...:.:..:.|.||...:...|    .....
 Worm   286 FEP----------------AIRLMFGKC-----NKFSQNKTYLDIFKDIEKIGPWP----VLKSD 325

  Fly   183 WVQTLGELRRNYGLDILLGL-EI---DLNLQTMKGNTIYFGE-PKLTIIPAEHCNALATRGAQVR 242
            ||..:..|.     |.||.| |:   |..|..::...:.||: |  .|.|:|.     .:|.|:.
 Worm   326 WVDVMFNLN-----DYLLSLVELGFTDFGLFKLEFRQLAFGQFP--VIAPSEQ-----KQGNQLE 378

  Fly   243 DEVYELVQ--------QQVTENLRDWFGMDT--------GEAARFAGDIIRFEFELCKQMGEQDI 291
            ..:.|:::        |::::.||::....:        |.:.::    ||:............:
 Worm   379 KIILEILEANGVQADRQKLSKYLREYSEFKSQLRHMSLEGTSVKY----IRYNASTLSVNISALV 439

  Fly   292 QKPEEEFPPAIQAQIYGARSRTGQERLRRQKGGMTLTELTSEMGNHLDFKMLVEVILESQYPSQV 356
            ||.              |...|....:||.:.|:.:|..:|..|.:||
 Worm   440 QKM--------------APMSTSSGLVRRIQSGILITNSSSFFGKNLD----------------- 473

  Fly   357 YLRSPEYVKHVVRTVKANNRITVGGYILYVALNELNQPPEEAPSQRARQCVQVTQRLFPQVLGEM 421
                        ..::..::.|:..|:::..::.:...............:.:..|...|||.:.
 Worm   474 ------------AIIQQTHKRTLANYLIFHFIDAVTFDLTSGAKHSEHTLIDLLPRGSLQVLSQD 526

  Fly   422 F--------QRHVQRDNAKHDLDAVFNDVIKALEE-----QFHVEWMDENDRRAARTRLSQYRVS 473
            |        ...:.:|..||        |::.:.|     :.|:.: :|.:||....::....|
 Worm   527 FVDEEDQGVMVEMAKDLKKH--------VVEMISEGSSLDKGHLVF-EEKERRKLIRKVQDILV- 581

  Fly   474 LPDYQSLDLTDLQFQK-----SEDYWRRLEIALKYRSHQQFEALRGNDFGQDADGLDAFEVRAAL 533
            :..| .|::.:..|:|     |:...:.::...::||.|..|.|.|:                 |
 Worm   582 VTKY-PLEILNQNFEKLNLTYSDSLHKIIQKLRRFRSEQLIEYLGGD-----------------L 628

  Fly   534 SPRQQMVLVGWG----------------LLQAPYYNYYYPKSLKYALLGHRLASALVQAFD---- 578
            .|..:.:   ||                ::..||::..||..:....:|..::..|.::.|
 Worm   629 DPTDKGM---WGSAHYEQATNDLIIIAPIIDGPYFDTSYPNYVNIFFMGFIISRELGRSLDSVRI 690

  Fly   579 --DEGWNNHPQATAQW-NEVTMSGYRNASECQRAQYSSYLYNEPGEFRNATR-LREIIADGSGLN 639
              ||  ..|   |..| ...::..:.|..:|.|.:.:            .|| |.|::||..|..
 Worm   691 RKDE--KGH---TENWLKSESLKRFDNNVKCWRKKIT------------GTRFLNEMLADHVGHE 738

  Fly   640 LAFNAYLAWLEQQDHKLRPLLAKETLSELNFTNTQLFF----IYFAQTRCWAKDNQDAILDSMPL 700
            .:|.|...|    :.::...:.::.....:.|..|:||    :||    |.........|.:...
 Worm   739 ASFMALKKW----EKEMNGTIVEKIRGYESMTMEQIFFHLQALYF----CRPPGGSTGELTAKDA 795

  Fly   701 MQHTPERWDVNGPLSNSAEFGREFGCALGTPMNSGDKCLVY 741
            .||...|  ||....|..:|.:.|||:....|||..||..:
 Worm   796 RQHYSTR--VNEAFKNMPQFAKAFGCSSNQNMNSKTKCTFF 834

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl13	NP_651096.1	PepO	63..732	CDD:226118	131/738 (18%)
		M13	68..738	CDD:189000	132/739 (18%)
nep-20	NP_001317749.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920