DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Nepl13 and nep-4

DIOPT Version :9

Sequence 1:	NP_651096.1	Gene:	Nepl13 / 42699	FlyBaseID:	FBgn0039022	Length:	741	Species:	Drosophila melanogaster
Sequence 2:	NP_509156.2	Gene:	nep-4 / 183746	WormBaseID:	WBGene00016896	Length:	437	Species:	Caenorhabditis elegans

Alignment Length:	223	Identity:	48/223 - (21%)
Similarity:	81/223 - (36%)	Gaps:	63/223 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   545 GLLQAPYYNYYYP-----KSLKYALLGHRLASALVQAFDDEGWNNHPQATAQWNEVTMSGYRNAS 604
            |.:...:.|||:.     ::.|....|.|:...:...|.:...|  |.....::       :.|.
Worm   243 GTIYFGFPNYYHTTYGNWRASKLGYTGTRVGHEIGHTFIEHSIN--PDGLPYFS-------KPAE 298

  Fly   605 ECQRAQY------------------SSYLYNEPGEFRNATRLREIIADGSGLNLAFNAYLAWLEQ 651
            :|.:.||                  |.|.:::.|            ||..||.||:    |.||:
Worm   299 DCVQNQYLKTCNEYYEGEVPDACNTSDYTFDDNG------------ADVFGLQLAY----AILER 347

  Fly   652 Q-DHKLRPLLAKETLSELNFTNTQLFFIYFAQTRCWAKDNQDAILDSMPLMQHTPERWDVNGPLS 715
            . ..:||     |....|..||.||.|..||...|  :.::....|.    .|:.....:|. ::
Worm   348 DLSDQLR-----EQADGLKITNEQLLFYSFAYRFC--RGSKSNTTDG----SHSHHNVRINA-VA 400

  Fly   716 NSAEFGREFGCALGTPM--NSGDKCLVY 741
            ....|.:.|.||..:.|  ::..:|::|
Worm   401 QMPGFQQAFNCASDSRMMKSATKQCVIY 428

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nepl13	NP_651096.1	PepO	63..732	CDD:226118	45/210 (21%)
Nepl13	NP_651096.1	M13	68..738	CDD:189000	46/218 (21%)
nep-4	NP_509156.2	GluZincin	250..425	CDD:387391	45/211 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000