Protein Alignment Nepl13 and nep-21

DIOPT Version :10

• Sequence 1: NP_651096.1
• Gene: Nepl13 / 42699
• FlyBaseID: FBgn0039022
• Length: 741
• Species: Drosophila melanogaster
• Sequence 2: NP_001360525.1
• Gene: nep-21 / 179925
• WormBaseID: WBGene00011794
• Length: 864
• Species: Caenorhabditis elegans
• Alignment Length: 793
• Identity: 170/793 - (21%)
• Similarity: 305/793 - (38%)
• Gaps: 148/793 - (18%)

  Fly    17 LLFEIQLCDVTEARQNHMNRMQMSGNFPDSREEQLVRQKIATDVQKYMNLSADPCTDFFEYACGQ 81
            |.||.....|..:.:||.:.:..|        .:.||  :|..:.:.:|...:||.||:|:|||.
 Worm   152 LPFENSSVAVDRSAKNHNDVVCTS--------RECVR--LAGFLAENLNSKINPCEDFYEFACGN 206

  Fly    82 WGRYHKRQLRPDELSTAQQLMETKISEQLQQLLTQPLPPQHHPNGYSGASMTNVRKVRAFYESCV 146
            :| .:|.......|......:::::::|::.:|..|:.....|..         :..:.:|:.|:
 Worm   207 YG-LNKNLPANKPLRHTISDVQSRLNKQVKSMLQSPISANEKPWD---------KVAKGYYQKCL 261

  Fly   147 AVEANASERRRFLMKILKDNGGLRNVPNSNWQH-NRQWVQTLGELRRNYGLD-ILLGLEIDLNLQ 209
            ..|...|.....:..|.|..||...:....||. :..|.:.:..:....|:: ::|.:.:..:..
 Worm   262 DEEELESTGVEAMRDIAKRIGGWPTLEGDKWQEWSHSWEEQIALVLNLTGVNAVILEMAVTHDPS 326

  Fly   210 TMKGNTIYFGEPKLTIIPAEHCNALATRGAQVRDEVYELVQQQVTENLRDW----------FGMD 264
            ....:.|...:||.              ||..|   |..:.......||::          .|.|
 Worm   327 NSSRSVIELDQPKW--------------GAGSR---YPYLSGANDPMLRNYTTLMKMTAVALGAD 374

  Fly   265 TGEAARFAGDIIRFEFELCKQMGEQDIQKPEEEFPPAIQAQIYGARSRTGQERLRRQKGGMTLTE 329
            ...|.:...:.:.||.:|.....:..:::..|.                |..|..       |.:
 Worm   375 PAIAEKEMNEAMEFELKLVNFSADDMVRRDPER----------------GNNRFE-------LWQ 416

  Fly   330 LTSEMGNHLDFKMLVEVI---LESQYPSQ-VYLRSPEY---VKHVVRT----VKANN---RITVG 380
            |.| :...::|:..::.:   |.:..|:. |.:|..:|   ::||:::    |.||.   |:..|
 Worm   417 LKS-VFPFINFEKYLKTVFKELVALSPNHTVIVREIDYFVGIQHVLQSTPKRVLANYISWRLVQG 480

  Fly   381 G----YILY--------------VALNE---LNQPPEEAPSQRARQCVQVTQRLFPQVLGEMF-Q 423
            |    |..:              ...|:   .|.||.:    |...||.::..:....:|.:| :
 Worm   481 GPTGDYFSFSPFLPPSAREPFYQFKANQTGMFNSPPPD----RWEDCVTLSVIMMDMPVGRLFVE 541

  Fly   424 RHVQRDNAKHDLDAVFNDVIKALEEQFHV-EWMDENDRRAA--RTRLSQYRVSLPDYQSLDLTDL 485
            ...:::.|...:..:.:.:.....:|.|| :||||..||.|  :..:.:|:...|   .:...|.
 Worm   542 NFFEKERAMKKMTELTSYLKNEFIKQLHVLDWMDEITRRRAISKANMIEYKSGFP---MVLFNDT 603

  Fly   486 QFQKS-------EDYWRRLEIALKYRSHQQFEALRGNDFGQDADGLDAF----EVRAALSPRQQM 539
            ..:|:       .:|...|.|.:|.....: |.||   ..|..|....|    :|.|..:|....
 Worm   604 WMEKNWGMIIKPREYLLHLTIRVKLVRFTE-ELLR---LDQPLDRSMWFQSPAQVDAYYAPNNNE 664

  Fly   540 VLVGWGLLQAPYYNYYYPKSLKYALLGHRLASALVQAFDDEG--WNNHPQATAQWNEVTMSGYRN 602
            ::...|::|.|:.....|..:.|.::|..:...:..||||:|  ::........|:..|...:..
 Worm   665 MIFPAGIMQFPFLTLGVPNYITYGMVGAVIGHEVSHAFDDQGGQYDEMGNLNDWWDAETEEKFIE 729

  Fly   603 ASECQRAQYSS-YLYNEPGEFRNATRLREIIADGSGLNLAFNAYLAWLEQQDHKLRPLLAKETLS 666
            .:.|...||.: ::............|.|.|||..|:..|||||.||.........|.|.    .
 Worm   730 KTRCFVRQYENVHVVEADIHLNGQLSLGENIADNGGVKTAFNAYKAWKSNTTGISEPALP----G 790

  Fly   667 ELNFTNTQLFFIYFAQTRC---WAKDNQDAILDSMPLMQHTPERWDVNGPLSNSAEFGREFGCAL 728
            ..|||:.|:||:.:|...|   ..|.....||..:    |.|.::....||.|..||.:.|.|.:
 Worm   791 FQNFTSQQMFFLAYANNWCSLVRPKHYIQIILTDV----HAPSKYRAMIPLQNRPEFAKAFQCPI 851

  Fly   729 GTPMNSGDKCLVY 741
            |:|||...||.|:
 Worm   852 GSPMNPERKCQVW 864

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl13	NP_651096.1	M13	68..738	CDD:341056	156/737 (21%)
nep-21	NP_001360525.1	M13	193..862	CDD:341056	157/738 (21%)