Protein Alignment Nepl13 and nep-16

DIOPT Version :9

• Sequence 1: NP_651096.1
• Gene: Nepl13 / 42699
• FlyBaseID: FBgn0039022
• Length: 741
• Species: Drosophila melanogaster
• Sequence 2: NP_001023203.2
• Gene: nep-16 / 177541
• WormBaseID: WBGene00018472
• Length: 868
• Species: Caenorhabditis elegans
• Alignment Length: 801
• Identity: 151/801 - (18%)
• Similarity: 270/801 - (33%)
• Gaps: 194/801 - (24%)

  Fly     6 SAWLGFLLELLLLFEIQLCDVTEARQNHMNRM-QMSGNFPDSREEQLVRQKIATDVQKYMNLSAD 69
            |.|||.|..|..|..|.|..|.....:....: ..|.|..::|  |.:  .||..:...::...:
 Worm   195 SIWLGALCALFFLLSIALFLVWVITTDGFRTIGAKSTNVCNTR--QCI--DIAFRLSSCIDDEIE 255

  Fly    70 PCTDFFEYACGQWGRYHKR----------QLRPDELSTAQQLMETKISEQLQQLLTQPLPPQHHP 124
            ||.:|:.|:|   .|||.:          ||:.:.|.....|:.   ||:..:||.:
 Worm   256 PCENFYRYSC---QRYHSQTADKQMSFLSQLKDESLRRMHSLLS---SEEDSRLLPK-------- 306

  Fly   125 NGYSGASMTNVRKVRAFYESCVAVEANASERRRFLMKILKD---NGGLRNVPNSNWQHNRQWVQT 186
                     :.|..|:.|.:|:.....:|.....|:..:::   ...||:..|.: ..:..|.:.
 Worm   307 ---------SARLSRSLYSACMNAVLRSSNAPTDLLTFIRNFPCGPLLRDCQNFH-ADSYSWERH 361

  Fly   187 LGELRRNYGLDILLGLEIDLNLQTMKGNTIYFGEPKLTIIPAEHCNALATRGAQVRD-------- 243
            .|.|....|...|:..:.|::.|......:....|.||.|.          |...||
 Worm   362 AGMLDWYAGRYNLIVYDRDVHPQDRSKIILQIKPPDLTPIV----------GLIERDLIDLARPS 416

  Fly   244 --EVYELVQQQVTENLRDWFGMDTGEAARFAGDIIRFEFELCKQMGEQDIQKPEEEFPPAIQAQI 306
              |...|:|..:.:||...|..|:         ::|         ..:|:|...:|....:....
 Worm   417 PTEFEPLLQLSLRQNLLSAFARDS---------LLR---------DPRDVQSQLDEVARLMVDLY 463

  Fly   307 YGARSRTGQERLRRQKGGMTLTELTSEMGNHLDFKMLVEVILESQY----PSQVYLRSPEYVKHV 367
            ..||....   |......||:.|:...: ..|..:..::..|.:.|    ...:.::..:|...:
 Worm   464 ISARQSAS---LTPNTTYMTIGEMFQAL-PQLYLREFLDAQLSNTYRWTETDMLSIQDYDYFARL 524

  Fly   368 VRTVKANNRITVGGYILYVALNELNQPPEEAPSQRA-RQCVQVTQRLFPQVLGEMFQRHVQRDNA 431
            ...:...:|..|..|:|.|.:..|.|.......|.. |:||.       |:......|.:..|.|
 Worm   525 SDIMAQTSRQAVANYLLTVTVWNLKQYSYSPRDQYGWRECVD-------QISSFEIGRKMYVDKA 582

  Fly   432 KHDLD-AVFNDVIKALEEQFHVEWMDENDRRAARTRLSQYRVSLPDYQSLDLTDLQF-------- 487
            ...:| ....:.::.|:..|                ||.:|.:...|.| ::..|.|
 Worm   583 SQTIDLPKIQEFLQNLKIDF----------------LSVHRSTPLQYLS-NINRLGFYVGFPRRL 630

  Fly   488 QKSEDYWRRL-EIALKYRSHQQFEAL-------RGNDFGQ-----DADGLDAFEV---RAALSPR 536
            |..|..|:.: :::|....:  |:::       |.....|     |.|....|.:   ....:..
 Worm   631 QNEELIWKPVSQVSLNETDY--FDSMIRVGKAERDYTMSQIGTYLDNDDTTTFPISDPTMLYNSN 693

  Fly   537 QQMVLVGWGLLQAPYY--NYYYPKSLKYALLGHRLASALVQAFDDEGWNNHPQATAQWNEVTMSG 599
            ...:::....::.|.|  ....|....|:.||......:.:.|    |....: |:|
 Worm   694 VGAIVIPLAFIEPPIYLPGDEVPMYGIYSSLGITTLQMISKVF----WQGLDK-TSQ-------- 745

  Fly   600 YRNASECQRAQYSSYLYNEPGEFRNATRLR------EIIAD---GSGLNLAFNAYLAWLEQQDHK 655
                .||        |.|....|.:|.|.|      |::|.   ......|..:|..|  |.||.
 Worm   746 ----LEC--------LDNVFRGFLDANRQRSPNIEPELLATIELADAFKSALYSYAKW--QNDHH 796

  Fly   656 LRPLLAKETLSELNFTNT-QLFFIYFAQTRCWAKDNQ-DAILDSMPLMQHTPERWDVNGPLSNSA 718
            :.   .::||...:.|:: :...:.|:...|..:.:: .:..::|           :|....||.
 Worm   797 IH---HEKTLPAFDSTDSMRSLMLTFSTMFCSGEGSEPGSDYEAM-----------INTVAENSR 847

  Fly   719 EFGREFGCALGTPMNSGDKCL 739
            .|...|.|...:.:.:...||
 Worm   848 MFSIHFNCNNSSRLYNRRTCL 868

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl13	NP_651096.1	PepO	63..732	CDD:226118	133/734 (18%)
		M13	68..738	CDD:189000	133/735 (18%)
nep-16	NP_001023203.2	GluZincin	254..>725	CDD:387391	99/552 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010