Protein Alignment Nepl13 and nep-3

DIOPT Version :9

• Sequence 1: NP_651096.1
• Gene: Nepl13 / 42699
• FlyBaseID: FBgn0039022
• Length: 741
• Species: Drosophila melanogaster
• Sequence 2: NP_494679.2
• Gene: nep-3 / 173730
• WormBaseID: WBGene00016778
• Length: 634
• Species: Caenorhabditis elegans
• Alignment Length: 774
• Identity: 163/774 - (21%)
• Similarity: 270/774 - (34%)
• Gaps: 215/774 - (27%)

  Fly    12 LLELLLLFEIQLC--DVTEARQNHMNRMQMSGNFPDSREEQLVRQKIATDVQKYMNL---SADPC 71
            :|.|:||.|....  :|:|...||    ..|...|..:...|..:.| |.|.:.:|.   |.|||
 Worm    26 ILPLVLLLEAGKIGGEVSENCSNH----STSSASPKPKPMCLTPECI-TLVHQLLNFQDPSVDPC 85

  Fly    72 TDFFEYACGQWGRYHKRQLRPDELSTAQQLMETKISEQLQQLLTQPLPPQHHPNGYSGASMTNVR 136
            .:|::.|||::..::              :::...:.|.||::.:.:....|.|..|.:...|..
 Worm    86 ENFYQAACGKYNEHN--------------VIDGSRTAQKQQIVKRLIRDFLHKNQSSTSKSENSM 136

  Fly   137 KVRAFYESC-----VAVEANASERRRFLMKILKDNGGLRNVPNSNWQHNRQWVQTLGELRRNYGL 196
            |:  .||.|     :.|..|.:..:...|.|.|.  |...|.:.||.
 Worm   137 KL--LYEKCKEAKTIKVLGNQNLLQEIFMNIQKI--GSWPVLDENWD------------------ 179

  Fly   197 DILLGLEIDLN---LQTMKGNTIYFGEPKLTIIPAEHCNALATRGAQVRDEVYELVQQQVTENLR 258
                |.:.:||   |..::.....||..::.|...........|....|:.:.:::.:....|
 Worm   180 ----GKKFNLNEMLLSLIRLGVSNFGFFEIIISSDAFVEIKPARNFPTRENLSDIISKVFLGN-- 238

  Fly   259 DWFGMDTGEAARFAGDIIRFEFELCKQMGEQDIQKPEEEFPPAIQAQIYGARSRTGQERLRRQKG 323
                       .|..:|...|.:|.:.   :::|:..:.....||
 Worm   239 -----------GFQPNITAIENDLREY---ENLQRELKSLERLIQ-------------------- 269

  Fly   324 GMTLTELTSEMGNHLDFKMLVEVILESQYPSQVYLRSPEYVKHVVRTVKANNRITVGGYILYVAL 388
                |.....:.|:|.|..|..|:||       |.|.||
 Worm   270 ----TTPNRSLVNYLIFNYLKSVMLE-------YKRLPE-------------------------- 297

  Fly   389 NELNQPPEEAPSQRARQCVQVTQRLFPQVLGEMF-QRHVQRDNAKH------DLDAVFNDVIKAL 446
                           .||..|.....|:....:| |..:.::|.|:      |:...|.|:|:
 Worm   298 ---------------EQCEGVVIDFLPRASTRVFVQNFLDKENRKYVAGMIEDVKMGFIDMIQ-- 345

  Fly   447 EEQFHVEWMDENDRRAARTRLSQYR--VSLPDY----QSLD--LTDLQFQKSEDYWRRLEIALKY 503
                ...|::|..::.|..::...:  :..||:    .:||  ..||..::::.|...:....|:
 Worm   346 ----ESTWLNEESKKVAVQKVKNIKSMIGYPDFFEPPGTLDRSFKDLNIEQTDSYHTIVRKIQKF 406

  Fly   504 RSHQQFE-------------ALRGNDFGQDADGLDAFEVRAALSPRQQMVLVGWGLLQAPYYNYY 555
            .:.|..|             .|..|.|.|:.:.|      |.|:|          :|..|.::..
 Worm   407 TNEQCMEFVASEIPLDPRQPILHANAFYQNTNFL------AILAP----------VLDDPIFDTT 455

  Fly   556 YPKSLKYALLGHRLASALVQAFDDEGWNNHPQATAQ--W-NEVTMSGYRNASECQRAQYSSYLYN 617
            :|:.:..|::|:.||..:..|||..| .|:..|..|  | .......|.....|...|:..  |:
 Worm   456 FPRYVNLAVIGNVLAHEIGHAFDHTG-INYDDAGQQRIWLTPEDSEEYGKRLRCLLRQHDE--YD 517

  Fly   618 EPGEFRN---ATRLREIIADGSGLNLAFNAYLAWLEQQDHKLRPLLAKETLSELNFTNTQLFFIY 679
            :|...||   :..|.||.||..|:..|:..:        .||......|.:...||...||:|..
 Worm   518 DPDFGRNLNGSKTLHEISADRFGVEAAWRTF--------KKLDLSNESEIVGFQNFNIDQLYFRT 574

  Fly   680 FAQTRCWAKDNQDAILDSMPLMQHTPERWDVNGPLSNSAEFGREFGCALGTPMNSGDKC 738
            .|...|..:|..|  |......:|....:.|||..:|..:|...|.|.||:|||...||
 Worm   575 AALIWCRQRDTTD--LQYALQREHPTNNFRVNGIYANMPQFAETFNCPLGSPMNPKKKC 631

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl13	NP_651096.1	PepO	63..732	CDD:226118	143/713 (20%)
		M13	68..738	CDD:189000	144/711 (20%)
nep-3	NP_494679.2	M13	82..631	CDD:189000	144/711 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.920