Protein Alignment Nepl13 and nep-11

DIOPT Version :10

• Sequence 1: NP_651096.1
• Gene: Nepl13 / 42699
• FlyBaseID: FBgn0039022
• Length: 741
• Species: Drosophila melanogaster
• Sequence 2: NP_494538.1
• Gene: nep-11 / 173685
• WormBaseID: WBGene00017557
• Length: 848
• Species: Caenorhabditis elegans
• Alignment Length: 766
• Identity: 173/766 - (22%)
• Similarity: 299/766 - (39%)
• Gaps: 164/766 - (21%)

  Fly    55 KIATDVQKYMNLSADPCTDFFEYACGQWGRYHKRQLRPDEL---STAQQLMETKISEQLQQLLTQ 116
            :.||.....||.|.|||.||||:|||||...|.   .||::   .|.....| ::.:||:.||.|
 Worm   168 RAATHFLNAMNTSVDPCDDFFEFACGQWNDQHP---IPDDMYGFGTFAYARE-QVRQQLRVLLEQ 228

  Fly   117 PLPPQHHPNGYSGASMTNVRKVRAFYESCVAVEANASERRRF----LMKILKDNGGLRNVP--NS 175
            .:..:..          ::...||.|.||:    |.::....    |.:.|.:.|   ..|  ..
 Worm   229 EVVTESE----------SINMARATYRSCM----NKTQLDELMTGPLFETLTELG---EWPLLQE 276

  Fly   176 NWQHNR-QWVQTLGELRRNYGLDILLGLEIDLNLQTMKGNTIYFGEPKLTIIPAEHCNALATRGA 239
            ||...: .:...|...||:||:|:...|.|..:.:....||::..:..|.:            |.
 Worm   277 NWDKTKFNFTSLLVNSRRDYGVDVFFQLYIYADSKNTSRNTLFIDQSTLAL------------GR 329

  Fly   240 QVRD------------EVYELVQQQVTENLRDWFGMDTGEAARFAG--DIIRFEFELCKQMGEQD 290
            ..||            ..|....:|:...|:....:...|:...|.  .||.||.||.|.:..:|
 Worm   330 GTRDYYLNTTLFSSHMTAYRKYLRQIAHLLKTDGNLTRSESEMNADIEKIIDFEIELAKIIVAED 394

  Fly   291 IQKPEEEFPPAIQAQIYGARSRTGQERLRRQKGGMTLTELTSEMGNHLDFKMLVEVILESQY--- 352
                                .|....||..::....|..|..:    :|:....:.|..|..
 Worm   395 --------------------ERRNNTRLYNKRQIQDLYNLLPQ----VDWVPFFQSIAPSDLTHL 435

  Fly   353 ---PSQVYLRSPEYVKHVVRTVKANNRITVGGYILY-----------------------VALNEL 391
               .:::.:...||::||...::..:...:..|:|:                       |...:.
 Worm   436 FHNETEIIICEIEYLQHVSELIEKTDVGLLTNYVLWRVVQSNVRYLDERFEDIKQDFLKVMTGQQ 500

  Fly   392 NQPPEEAPSQRARQCVQVTQRLFPQVLGEMF-QRHVQRDNAKHD-------LDAVFNDVIKALEE 448
            ..||      |.:.|.||...:.|...|.:: |.|.| ::.||:       |...|.|:::
 Worm   501 QSPP------RWKDCAQVPSTVLPLAAGAIYVQAHFQ-ESDKHEALRMIMHLRNSFADLVR---- 554

  Fly   449 QFHVEWMDENDRRAARTRLSQY--RVSLPD-----------YQSLDLTDLQFQKSEDYWRRLEIA 500
              ..:||||..:..|..:.:..  .:..||           |..|.::|     |:.|:..::.:
 Worm   555 --QNDWMDEETKAVAIEKANSMINNIGYPDVTNDLPKLDKQYLGLSISD-----SDTYYYIMKKS 612

  Fly   501 LKYRSHQQFEALRGNDFGQDADGLDAFEVRAALSPRQQMVLVGWGLLQAPYYNYYYPKSLKYALL 565
            :.:...::|:.|. ..|.:....:....|.|..||.:..:....|:||.|:::..:||::.|..:
 Worm   613 VVWMQSREFQKLT-KPFDKHEFDISPAVVNAFYSPEKNAITFPAGILQPPFFSGTFPKAVNYGAI 676

  Fly   566 GHRLASALVQAFDDEG--WNNHPQATAQWNEVTMSGYRNASECQRAQYSSYLYNEPGEFRNATRL 628
            |..:...:...|||:|  ::........|:|.:::.:.....|...||.:|...:. .||...:|
 Worm   677 GAVIGHEITHGFDDQGSQYDKDGNLHNWWSESSLNSFDTRRRCIVEQYGNYTVPKT-NFRVNGKL 740

  Fly   629 R--EIIADGSGLNLAFNAYLAWLEQQDHKLR-PLLAKETLSELNFTNTQLFFIYFAQTRCWAKDN 690
            .  |.|||..|:..||.||..::.:...:.| |.|.:       :||.|:||:.:|...| .|..
 Worm   741 TQGENIADNGGVKEAFQAYQKYVTENGEEPRLPGLQQ-------YTNEQIFFVSYAHFWC-GKKK 797

  Fly   691 QDAILDSMPLMQHTPERWDVNGPLSNSAEFGREFGCALGTPMNSGDKCLVY 741
            :.|.:..:...:|:||.:.|.|.|||...|...:.|....|:|...||:|:
 Worm   798 EAAAMQQVLTDEHSPEVFRVIGVLSNMQAFADVYKCPRNAPVNPDHKCIVW 848

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl13	NP_651096.1	M13	68..738	CDD:341056	165/748 (22%)
nep-11	NP_494538.1	M13	181..845	CDD:341056	165/748 (22%)