Protein Alignment Nepl13 and Ecel1

DIOPT Version :10

• Sequence 1: NP_651096.1
• Gene: Nepl13 / 42699
• FlyBaseID: FBgn0039022
• Length: 741
• Species: Drosophila melanogaster
• Sequence 2: NP_067281.2
• Gene: Ecel1 / 13599
• MGIID: 1343461
• Length: 775
• Species: Mus musculus
• Alignment Length: 791
• Identity: 200/791 - (25%)
• Similarity: 339/791 - (42%)
• Gaps: 147/791 - (18%)

  Fly    17 LLFEIQLCDVTEARQNHMNRMQM--------SGNFPDSREEQLVRQKIATDVQKYMNLSADPCTD 73
            |:|...||.:..|    |..::.        .|..|:...|:....:.|..:...::.|.|||.|
Mouse    66 LVFAAGLCAILAA----MLALKYLGPGAAGGGGACPEGCPERKAFARAARFLSANLDASIDPCQD 126

  Fly    74 FFEYACGQWGRYHKRQLRPDELS--TAQQLMETKISEQLQQLLTQPLPPQHHPNGYSGASMTNVR 136
            |:.:|||.|.|.|  .:..|:|:  |...:.|.. .|:|::||.:|      ..|..||:.   |
Mouse   127 FYSFACGGWLRRH--AIPDDKLTYGTIAAIGEQN-EERLRRLLARP------TGGPGGAAQ---R 179

  Fly   137 KVRAFYESCVAVEANASERRRFLMKILK-----DNGGLRNVPN-SNWQHNRQWVQTLGELRRNYG 195
            |||||:.||:.:........|.::::::     |.||..:.|. :.|..||...:..|.    |.
Mouse   180 KVRAFFRSCLDMREIERLGPRPMLEVIEDCGGWDLGGAADRPGAARWDLNRLLYKAQGV----YS 240

  Fly   196 LDILLGLEIDLNLQTMKGNTIYFGEPKLTIIPAEHCNALATRGAQVRDE-------VYELVQQQV 253
            ...|..|.:.|:.:......|...:..||:  .|....||      :||       .|.:..|::
Mouse   241 AAALFSLTVSLDDRNSSRYVIRIDQDGLTL--PERTLYLA------QDEESEKILAAYRVFMQRL 297

  Fly   254 TENLRDWFGMDTGEAARFAGDIIRFEFELCK-QMGEQDIQKPEEEFPPAIQAQIYGARSRTGQER 317
            ...|    |.|..|  :.|.:|::.|..|.. .:.|.|          .::..:..|.::
Mouse   298 LRLL----GADAVE--QKAQEILQLEQRLANISVSEYD----------DLRRDVSSAYNK----- 341

  Fly   318 LRRQKGGMTLTELTSEMGNHLDFKMLVEVILESQY--PSQVYLRSPEYVKHVVRTVKANNRITVG 380
                   :||.:| .::..||.:|.|::.|.:..:  ..:|.|.:.:|::.|.:.:::..|..:.
Mouse   342 -------VTLGQL-QKIIPHLQWKWLLDQIFQEDFSEEEEVVLLATDYMQQVSQLIRSTPRRILH 398

  Fly   381 GYILY---VALNE-LNQPPEEA-------------PSQRARQCVQVTQRLFPQVLGEMFQRHVQR 428
            .|:::   |.|:| |:.|..||             |.:.||.|:....|.|...||.:|......
Mouse   399 NYLVWRVVVVLSEHLSSPFREALHELAKEMEGNDKPQELARVCLGQANRHFGMALGALFVHEHFS 463

  Fly   429 DNAKHDLDAVFNDVIKALEEQF-HVEWMDENDRRAARTRLSQY---RVSLPDY----QSLDLTDL 485
            ..:|..:..:..|:...|.::. .::|||...:.|||.:| ||   .|..||:    :::| .:.
Mouse   464 AASKAKVQQLVEDIKYILGQRLEELDWMDAQTKAAARAKL-QYMMVMVGYPDFLLKPEAVD-KEY 526

  Fly   486 QFQKSE-DYWRRLEIALKYRSHQQFEALRGNDFGQDAD---------GLDAFEVRAALSPRQQMV 540
            :|:..| .|::.:..::::......:.:|     |:.|         .|:|:    .|..:.|||
Mouse   527 EFEVHEKTYFKNILNSIRFSIQLSVKKIR-----QEVDKSSWLLPPQALNAY----YLPNKNQMV 582

  Fly   541 LVGWGLLQAPYYNYYYPKSLKYALLGHRLASALVQAFDDEG--WNNHPQATAQWNEVTMSGYRNA 603
            ... |:||...|:..:|:||.|..:|..:...|...:||.|  ::........|.|.:.|.:...
Mouse   583 FPA-GILQPTLYDPDFPQSLNYGGIGTIIGHELTHGYDDWGGQYDRSGNLLHWWTETSYSHFLRK 646

  Fly   604 SECQRAQYSSY-LYNEPGEFRNATRLREIIADGSGLNLAFNAYLAWLEQQ--DHKLRPLLAKETL 665
            :||....|.:: :||:  .......|.|.|||..||.||:.||..|:.:.  :|.|.
Mouse   647 AECIVRLYDNFTVYNQ--RVNGKHTLGENIADMGGLKLAYYAYQKWVREHGPEHPLH-------- 701

  Fly   666 SELNFTNTQLFFIYFAQTRCWAKDNQDAILDSMPLMQHTPERWDVNGPLSNSAEFGREFGCALGT 730
             .|.:|:.|||||.|||..|..:.:|...|..: ..:|.||.:.|.|.:|...||||.|.|...:
Mouse   702 -RLKYTHNQLFFIAFAQNWCIKRRSQSIYLQVL-TDKHAPEHYRVLGSVSQFEEFGRAFHCPKDS 764

  Fly   731 PMNSGDKCLVY 741
            |||...||.|:
Mouse   765 PMNPVHKCSVW 775

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl13	NP_651096.1	M13	68..738	CDD:341056	186/727 (26%)
Ecel1	NP_067281.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	30..52
		M13	121..773	CDD:341056	187/728 (26%)