Protein Alignment Nepl13 and Nep2

DIOPT Version :10

• Sequence 1: NP_651096.1
• Gene: Nepl13 / 42699
• FlyBaseID: FBgn0039022
• Length: 741
• Species: Drosophila melanogaster
• Sequence 2: XP_061497288.1
• Gene: Nep2 / 1281326
• VectorBaseID: AGAMI1_002834
• Length: 792
• Species: Anopheles gambiae
• Alignment Length: 742
• Identity: 172/742 - (23%)
• Similarity: 304/742 - (40%)
• Gaps: 126/742 - (16%)

  Fly    57 ATDVQKYMNLSADPCTDFFEYACGQWGRYHKRQLRPDELSTAQ--QLMETKISEQLQQLLTQPLP 119
            |:...:.|:...:||.||:.|||   |::.|..:.|||..:..  .::..::.:||:.|:::.:
Mosquito   120 ASKALEQMDQEVEPCDDFYNYAC---GKFVKETVIPDEKVSVNTFSVIGDRLQQQLRSLVSEEI- 180

  Fly   120 PQHHPNGYSGASMTNVRKVRAFYESCVAVEANASERRRFLMKILKDNGGLRNVPNSNW--QHNRQ 182
                    |.:..|..:..:..|:.|:.......:..:.|:.|.:..||...:...:|  ..:..
Mosquito   181 --------SDSEATPFKLAKNLYKLCMNKTRIEEKGIKPLLDIHEVLGGWPVLKGDSWDLDSSWS 237

  Fly   183 WVQTLGELRRN-YGLDILLGLEI--DLNLQTMKGNTIYFGEPKLTIIPAEHCNALATRGAQVRDE 244
            ||:::.:.|.| |..|......|  ||...|.:            ||..:..:...:|...|:..
Mosquito   238 WVKSVKDFRNNGYSTDYFFDFSIGSDLKNSTRR------------IIDTDQASLGISREYLVKGM 290

  Fly   245 VYELVQ--QQVTENLRDWFGMDTGEAARFAGDIIRFEFELCKQMGEQDIQKPEEEFPPAIQAQIY 307
            ...:|.  .....::....|.|...|.|...|.:.||..|.      :|..|.|:...|  ..:|
Mosquito   291 ENPIVSAYYNYMVDMAVLLGADEERAKRELLDSLNFEMALA------NISLPNEKRRNA--TALY 347

  Fly   308 GARSRTGQERLRRQKGGMTLTELTS--------EMGNHL--DFKMLV---EVILESQYPSQVYLR 359
            ..               ||:.|...        |..|.:  |..:::   |||:.| .|:.:...
Mosquito   348 NP---------------MTVKEFQQRYPYTDWLEYFNAILKDTGIVIGEEEVIIVS-VPTFMEQL 396

  Fly   360 SPEYVKHVVRTVKANNRI-TVGGYILYVALNELNQ-----------PPEEAPSQRARQCVQVTQR 412
            .| .:::..:.|.||..: .:.|:..:....:|.:           ..|:.|  |.::||.:|..
Mosquito   397 GP-LLQNTPKRVMANYVMWRISGFSSFFLTEKLRKRQLQYSTALSGKQEQEP--RWKECVDITSG 458

  Fly   413 LFPQVLGEMFQRHVQRDNAK-------HDLDAVFNDVIKALEEQFHVEWMDENDRRAARTRLSQY 470
            ..|..:|.::.|...|:::|       :|:.:||.|::|      .|:||||..|.:|..::|..
Mosquito   459 SLPISVGALYIRKYFREDSKRAALDMVNDIKSVFVDILK------KVDWMDEVTRVSALEKVSTM 517

  Fly   471 --RVSLPDYQSLD-------LTDLQFQKSEDYWRRLEIALKYRSHQQFEALR--GNDFGQDADGL 524
              .:..|| :.:|       ..||:||....|...:....|:.:.:.|:.||  .|.........
Mosquito   518 ATHIGYPD-ELMDDAKIAEYYKDLEFQPDSTYLNTILYMNKFGTTKAFKKLRIAVNKTDWITHSR 581

  Fly   525 DAFEVRAALSPRQQMVLVGWGLLQAPYYNYYYPKSLKYALLGHRLASALVQAFDDEG--WNNHPQ 587
            .|. |.|..|..:..:....|:||..:::|..||.:.|..:|..:...:...|||:|  ::.:..
Mosquito   582 PAI-VNAFYSSIENSIQFPAGILQGQFFSYDRPKYMNYGAIGFVIGHEITHGFDDQGRQFDKNGN 645

  Fly   588 ATAQWNEVTMSGYRNASECQRAQYSSYLYNEPGEFRNATRLR---EIIADGSGLNLAFNAYLAWL 649
            ....|...|.:.|...:.|...||.:  |.||....|...:.   |.|||..|:..|:.||..|.
Mosquito   646 LVDWWQSDTKTAYLEKARCIIEQYGN--YTEPNVKLNLNGINTQGENIADNGGIKEAYYAYRRWT 708

  Fly   650 EQQDHKLRPLLAKETLSELNFTNTQLFFIYFAQTRCWAKDNQDAILDSMPLMQHTPERWDVNGPL 714
            |:...:.|       |..||.:..|:|::..|||.| :....:.:...:....|:|.::.|.||:
Mosquito   709 EKNGPEQR-------LPGLNLSPEQMFWLSAAQTWC-SVYRPETMKMRITTGVHSPGQFRVLGPM 765

  Fly   715 SNSAEFGREFGCALGTPMNSGDKCLVY 741
            ||..||.::|.|.:|:|||...||.|:
Mosquito   766 SNMHEFAKDFNCPVGSPMNPEHKCEVW 792

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl13	NP_651096.1	M13	68..738	CDD:341056	167/726 (23%)
Nep2	XP_061497288.1	None