Protein Alignment Nepl13 and Nep3

DIOPT Version :10

• Sequence 1: NP_651096.1
• Gene: Nepl13 / 42699
• FlyBaseID: FBgn0039022
• Length: 741
• Species: Drosophila melanogaster
• Sequence 2: XP_317711.2
• Gene: Nep3 / 1278166
• VectorBaseID: AGAMI1_011685
• Length: 789
• Species: Anopheles gambiae
• Alignment Length: 800
• Identity: 194/800 - (24%)
• Similarity: 334/800 - (41%)
• Gaps: 138/800 - (17%)

  Fly    12 LLELLLLFEIQLCDVTEARQNHMNRM----QMSGNFPDSREEQL--VRQK---IATDVQKYMNLS 67
            ||.||.|..|.:..::....:...|:    ...|:.|...:|||  :.|.   .|:::...::.|
Mosquito    58 LLSLLALSIILIVVLSSLLASDTTRILHVRPHVGSDPFGVDEQLPCLNQHCIFAASEILHSIDWS 122

  Fly    68 ADPCTDFFEYACGQWGRYHKRQLRPDELSTAQQL--METKISEQ----LQQLLTQPLPPQHHPNG 126
            .|||.||:.::|.||       :|.:.:...:.:  :..|:.:|    |:..|.:||
Mosquito   123 VDPCDDFYAFSCNQW-------IRNNPIPEGKSMWGLFGKLEQQNQLVLKNALERPL-------- 172

  Fly   127 YSGASMTNVRKVRAFYESCV----AVEANASERRRFLMKILKDNGGLRNVPNSNWQHNRQW--VQ 185
             :.......:|.:.:|:||:    .:|...:|.   |.|:|:..||.....|::....::|  .:
Mosquito   173 -AEFKSKAEKKAKLYYQSCLDEDETMEKLGAEP---LQKLLRQIGGWNVTANASGFDVQRWSLQR 233

  Fly   186 TLGELRRNYGLDILLGLEIDLNLQTMKGNTIYFGEPKLTIIPAEHCNALATRGAQVRDEVYELVQ 250
            ||..|:..|.:..|.|..:..:.:....:.|...:..|| :|:.......|..|::.....|.:.
Mosquito   234 TLQTLQIRYNMGGLFGWAVGEDDRNSSKHIIQIDQGGLT-LPSRDNYLNKTANAKILTAYLEYMT 297

  Fly   251 QQVTENLRDWFGMDTGEAARFAGDIIRFEFELCKQMGEQDIQKPEEE-FPPAIQAQIYGARSRTG 314
            :     :....|.|..:|.|...::|.||..|......||:::.||. :.|
Mosquito   298 K-----VSVLLGADETDARRQMLEVIEFETRLANITTPQDMRRDEETLYHP-------------- 343

  Fly   315 QERLRRQKGGMTLTELTSE-----MGNHLD--FKMLVEVILESQYPSQVYLRSPEYVKHVVRTVK 372
                      |||..|..:     ...|.:  |:::...|.|.:   :|.:.:|||::.:...:|
Mosquito   344 ----------MTLAMLQEKAPFINWQEHFEEAFRLVRRKITEKE---RVVVYAPEYLEKLNILMK 395

  Fly   373 A-----NNRITVGGYILYVALNELNQPPEEA-----------------PSQRARQCVQVTQRLFP 415
            .     ..:|.:..|:::..:..|.....:|                 ..:..|.||..|..:..
Mosquito   396 EYTSTDEKKIILNNYLVWQTVRTLTACLSKAFRDAYKGLRKALMGSDGGEELWRYCVSDTSNVLG 460

  Fly   416 QVLGEMFQRHVQRDNAKHDLDAVFNDVIKALEEQF-HVEWMDENDRRAARTRLSQY--RVSLPDY 477
            ..:|.||.|.|...::|...:.:.|.|..|.:|.| ::.|||...||.|..:....  .:..|||
Mosquito   461 FAVGAMFVRDVFHGDSKPQAEEMINQVRDAFKENFKNLGWMDAETRRLAVEKADAISDMIGFPDY 525

  Fly   478 ----QSLD--LTDLQFQKSEDYWRRLEIALKYRSHQQFEALRGNDFGQDADGLDAFEVRAALSPR 536
                :.||  ..||.......:...:...: |...:..|.| .....:...|:....|.|..:|.
Mosquito   526 ILYPEELDRKYQDLNIDPKTYFDNNINYNI-YSLKKNLEKL-DQPVNKTKWGMTPPTVNAYYTPT 588

  Fly   537 QQMVLVGWGLLQAPYYNYYYPKSLKYALLGHRLASALVQAFDDEG--WNNHPQATAQWNEVTMSG 599
            :..::...|:||.|:::....|||.|..:|..:...|..||||:|  ::.:......||..|:..
Mosquito   589 KNQIVFPAGILQNPFFDIKNSKSLNYGAMGVVMGHELTHAFDDQGREYDKYGNLHQWWNNQTIER 653

  Fly   600 YRNASECQRAQYSSYLYNEPGEFRNATR-LREIIADGSGLNLAFNAYLAWLEQQDHKLRPLLAKE 663
            ::|.:||...|||:|..|  |:..|..: :.|.|||..||..||:||:      :::.......:
Mosquito   654 FKNQTECFNQQYSAYRIN--GKTINGKQTMGENIADNGGLKAAFHAYI------NNEKNSYTDTD 710

  Fly   664 T--LSELNFTNTQLFFIYFAQTRCWAKDNQDAILDSMPLMQ-----HTPERWDVNGPLSNSAEFG 721
            |  |..:|.|:.||||:.|||..|      .|:.|....:|     |:|.::.|.|||||..||.
Mosquito   711 TLPLPGVNMTHRQLFFVSFAQVWC------SAVTDETTTLQIEKDSHSPPKYRVIGPLSNLKEFS 769

  Fly   722 REFGCALGTPMNSGDKCLVY 741
            ..|.|.|||.||..:||:|:
Mosquito   770 DTFHCPLGTGMNPIEKCVVW 789

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl13	NP_651096.1	M13	68..738	CDD:341056	176/730 (24%)
Nep3	XP_317711.2	None