Protein Alignment Nepl13 and Nep4

DIOPT Version :10

• Sequence 1: NP_651096.1
• Gene: Nepl13 / 42699
• FlyBaseID: FBgn0039022
• Length: 741
• Species: Drosophila melanogaster
• Sequence 2: XP_061501026.1
• Gene: Nep4 / 1273777
• VectorBaseID: AGAMI1_013990
• Length: 1007
• Species: Anopheles gambiae
• Alignment Length: 854
• Identity: 199/854 - (23%)
• Similarity: 315/854 - (36%)
• Gaps: 209/854 - (24%)

  Fly    30 RQNHMNRMQMS-GNFPDSREE-QLVRQKIATDVQKYMNLSADPCTDFFEYACGQWGRYHKRQLRP 92
            |...:.|::.| |...|.|.. :.||......:::||:..||||.||::||||.|.|.:......
Mosquito   221 RSEQLPRVRRSVGWMNDDRSSPESVRAAQVAIMKQYMDPDADPCDDFYQYACGNWDRVNPIPKDK 285

  Fly    93 DELSTAQQLMETKISEQLQQLLTQPLPP------------QHHPNG------------------- 126
            ..|.|.:.|.|: :...|:|||.:..|.            :..|:|
Mosquito   286 AALDTFELLRES-LDLVLKQLLLEGEPAGLLDVENALSTVRSQPDGTKKSTSTTTTAASAGWPTT 349

  Fly   127 ------------------------YSGASMTN--------VRKVRAFYESCVAVEANASERRRF- 158
                                    .||.::.|        |::||...|..:..:|....|..|
Mosquito   350 TVTGGPAQQQLHRVRKRGRAENRNRSGRAVQNKLIIRSAQVKRVRRKRELLINDDAEMKARHLFV 414

  Fly   159 ---------------LMKILKDNGGLRNVPNSNWQHNR-QWVQTLGELRRNYGLDILLGLEIDLN 207
                           |..:|...||...:....|..:. .|:.....||| |..|:|:...:..:
Mosquito   415 SCMNYELIERRGLEPLRTLLHSLGGWPVLEPHTWDESSFDWLNLTAALRR-YNNDVLIVEWVGPD 478

  Fly   208 LQTMKGNTIYFGEPKLTIIPAEHCNALATRGAQVRDEVYELVQQQVTENLRDWFGMDTG------ 266
            ::....|.:.|.:..|              |...||...:...::..|..|.:.....|
Mosquito   479 IKNSDENIVQFDQTSL--------------GLPTRDYYLQPGNRKYLEAYRQFMLEVIGLLDVPA 529

  Fly   267 EAARFAGD-IIRFEFELCKQMGEQDIQKPEEEFPPAIQAQIYGARSRTGQERLRRQKGGMTLTEL 330
            :.||.|.| :|.||.:|.      :|....||              |.....|.|:   :.|.:|
Mosquito   530 DTARQATDEMIEFETQLA------NITSTPEE--------------RNNVSTLYRK---LMLDQL 571

  Fly   331 TSEMGNHLDFKMLVEVILESQY--PSQVYLRSPEYVKHVVRTVKANNRITVGGYILY----VALN 389
            ..|: ..:::...:.::.|...  .|.|.:.:..|::.:|..:.......|..|:|:    ..:|
Mosquito   572 QEEV-PQINWTHYLTIVTERPVNGSSFVVMFAMSYMRDLVELIDQTEPRIVANYLLWRFVRHRIN 635

  Fly   390 ELN-------------------QPPEEAPSQRARQCVQVTQRLFPQVLGEMFQRHVQRDNAK--- 432
            .|:                   .||      |.:.||..........:|.||.|....:|:|
Mosquito   636 NLDDRFLGAKQRFSNALFGRERNPP------RWKNCVTQVNANMGMAVGAMFVRRYFDENSKRDT 694

  Fly   433 ----HDLDAVFNDVIKALEEQFHVEWMDENDRRAARTRLS--QYRVSLPDY----QSLDLTDLQF 487
                |:|...|.:::.      ...|:|...|:.|..:::  ..|:..||:    :.|.......
Mosquito   695 LTMTHELQDAFREILG------RTGWIDMATRQLAEQKVNAMSLRIGYPDFILDPEQLSARYATL 753

  Fly   488 QKSEDYWRRLEIALKYRSHQQFEALRGND---FGQDADGLDAFE-----VRAALSPRQQMVLVGW 544
            :...|  |..|..|...||     :|..|   .||..: ..|:.     |.|..|..:..::...
Mosquito   754 EIHPD--RYFENTLNVLSH-----IRRTDQEKLGQPVN-KTAWHTAPAVVNAYYSRNKNQIMFPA 810

  Fly   545 GLLQAPYYNYYYPKSLKYALLGHRLASALVQAFDDEG--WNNHPQATAQWNEVTMSGYRNASECQ 607
            |:||.|:|:.:.||::.|..:|..:...|...|||:|  ::........|::..:..:...:.|.
Mosquito   811 GILQPPFYHRHLPKAINYGGIGVVIGHELTHGFDDKGRLFDRDGNLYRWWSDRAIEEFHERAACL 875

  Fly   608 RAQYSSYLYNE-----PGEFRNATRLREIIADGSGLNLAFNAYLAWLEQQDHKLRPLLAKETLSE 667
            ..||..|...|     .||....    |.|||..|:..||.||..||..|..  |.:|..|||..
Mosquito   876 VEQYGRYRIAEVDVQLDGENTQG----ENIADNGGIKQAFLAYSKWLAAQTD--RRVLEAETLPG 934

  Fly   668 LNFTNTQLFFIYFAQTRCWAKDNQDAILDSMPLMQHTPERWDVNGPLSNSAEFGREFGCALGTPM 732
            ||.|.|||||:.|||..|.|. ..:|..:.:....|:|.|:.|.|.||||.:|.||:.|.:|:.|
Mosquito   935 LNVTRTQLFFLNFAQIWCGAM-RPEATRNKLKTAVHSPGRFRVIGTLSNSEDFAREYHCPVGSTM 998

  Fly   733 NSGDKCLVY 741
            |...||.|:
Mosquito   999 NPPGKCSVW 1007

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl13	NP_651096.1	M13	68..738	CDD:341056	186/809 (23%)
Nep4	XP_061501026.1	None