DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG31139 and POGLUT2

DIOPT Version :10

Sequence 1:NP_732797.1 Gene:CG31139 / 42698 FlyBaseID:FBgn0051139 Length:397 Species:Drosophila melanogaster
Sequence 2:NP_076994.2 Gene:POGLUT2 / 79070 HGNCID:19350 Length:502 Species:Homo sapiens


Alignment Length:388 Identity:115/388 - (29%)
Similarity:184/388 - (47%) Gaps:60/388 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly    44 PHILHALAIHRPC---------VIGDPKCLCHVATIQRDLE--PYVDKGITPEMMAQS--KRLG- 94
            |:||.....|..|         .:.:..|...:|.|||||.  |.||    ||.:|..  ||.| 
Human   125 PYILKGPVYHENCDCPLQDSAAWLREMNCPETIAQIQRDLAHFPAVD----PEKIAVEIPKRFGQ 185

  Fly    95 ----TFYQIIRGRIYRQQKCLHPKRCADVEDLLLDMASGV--ADLEFVLNVRDWP--------QV 145
                ..|.:...::|.:....|......::.:||.:...|  .|:|..:|:.|||        .:
Human   186 RQSLCHYTLKDNKVYIKTHGEHVGFRIFMDAILLSLTRKVKMPDVELFVNLGDWPLEKKKSNSNI 250

  Fly   146 HFLSGLSGPVFSYSITNRHLDIMYPAWSFWTTTGPILQHYPHGVGR--WDWMRKHLVARASELPW 208
            |       |:||:..:....||:.|.:..   |..:|:    .:||  .|.|.   |...:..||
Human   251 H-------PIFSWCGSTDSKDIVMPTYDL---TDSVLE----TMGRVSLDMMS---VQANTGPPW 298

  Fly   209 SAKRAIGFFRGSRSSPERDSLVRLSQRRPDLVDAQYT-ILATDADPVEKMPLVEHCQF------K 266
            .:|.:...:||..|..||..||:||::.|:|:||.:| ......|.....|:|:|..|      |
Human   299 ESKNSTAVWRGRDSRKERLELVKLSRKHPELIDAAFTNFFFFKHDENLYGPIVKHISFFDFFKHK 363

  Fly   267 YLFNFRGVAASFRLRHILLCRSLVLHVGDQWQEFFYSQLKPWVHYVPVASDADVDELAELILYLR 331
            |..|..|..|::||.::|:..|:||.....:.|.||::|:||.||:||.|  ::.:|.|.:.:.:
Human   364 YQINIDGTVAAYRLPYLLVGDSVVLKQDSIYYEHFYNELQPWKHYIPVKS--NLSDLLEKLKWAK 426

  Fly   332 EHDDLAEEIAERGQQFIWLHLRMEDVQCYWSKMLQEYAKLLTYKVQREPGLLEVSNKKAVQLY 394
            :||:.|::||:.||:|...:|..:|:.||:.|:.||||.|...:.|...|:..|..:....|:
Human   427 DHDEEAKKIAKAGQEFARNNLMGDDIFCYYFKLFQEYANLQVSEPQIREGMKRVEPQTEDDLF 489

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG31139NP_732797.1 Glyco_transf_90 61..397 CDD:310354 110/362 (30%)
POGLUT2NP_076994.2 Filamin 24..130 3/4 (75%)
IG_FLMN 29..129 CDD:214720 2/3 (67%)
Glyco_transf_90 151..484 CDD:310354 109/355 (31%)
Prevents secretion from ER. /evidence=ECO:0000255|PROSITE-ProRule:PRU10138 499..502
Blue background indicates that the domain is not in the aligned region.

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