DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG31139 and Poglut2

DIOPT Version :10

Sequence 1:NP_732797.1 Gene:CG31139 / 42698 FlyBaseID:FBgn0051139 Length:397 Species:Drosophila melanogaster
Sequence 2:NP_076134.1 Gene:Poglut2 / 72050 MGIID:1919300 Length:502 Species:Mus musculus


Alignment Length:399 Identity:117/399 - (29%)
Similarity:188/399 - (47%) Gaps:50/399 - (12%)


- Green bases have known domain annotations that are detailed below.


  Fly    26 KCAVNEHNPNSNTSYDFVPHILHALAIHRPC---------VIGDPKCLCHVATIQRDLE--PYVD 79
            |..|..|..:...|    |::|.....|..|         .:.:..|...::.||:||.  |.||
Mouse   111 KIEVKHHGQHVAES----PYVLRGPVYHENCDCPLEDSAAWLREMNCSETISQIQKDLAHFPTVD 171

  Fly    80 KGITPEMMAQS--KRLG-----TFYQIIRGRIYRQQKCLHPKRCADVEDLLLDMASGV--ADLEF 135
                ||.:|..  ||.|     ..|.:...::|.:....|......::.:||.:...|  .|:||
Mouse   172 ----PEKIAAEIPKRFGQRQSLCHYTLKDNKVYIKTHGEHVGFRIFMDAILLSLTRKVRMPDVEF 232

  Fly   136 VLNVRDWPQVHFLSGLS-GPVFSYSITNRHLDIMYPAWSFWTTTGPILQHYPHGVGR--WDWMRK 197
            .:|:.|||.....|..: .|:||:..:....||:.|.:..   |..:|:    .:||  .|.|. 
Mouse   233 FVNLGDWPLEKKKSNSNIQPIFSWCGSTESRDIVMPTYDL---TDSVLE----TMGRVSLDMMS- 289

  Fly   198 HLVARASELPWSAKRAIGFFRGSRSSPERDSLVRLSQRRPDLVDAQYT-ILATDADPVEKMPLVE 261
              |...:..||.:|.:...:||..|..||..||:||::.|:|:||.:| ......|.....|:|:
Mouse   290 --VQANTGPPWESKNSTAVWRGRDSRKERLELVKLSRKHPELIDAAFTNFFFFKHDESLYGPIVK 352

  Fly   262 HCQF------KYLFNFRGVAASFRLRHILLCRSLVLHVGDQWQEFFYSQLKPWVHYVPVASDADV 320
            |..|      ||..|..|..|::||.::|:..|:||.....:.|.||::|:||.||:||.|  ::
Mouse   353 HISFFDFFKHKYQINIDGTVAAYRLPYLLVGDSVVLKQDSIYYEHFYNELQPWKHYIPVKS--NL 415

  Fly   321 DELAELILYLREHDDLAEEIAERGQQFIWLHLRMEDVQCYWSKMLQEYAKLLTYKVQREPGLLEV 385
            .:|.|.:.:.:|||..|::||:.||:|...:|..:|:.||:.|:.|.||.|...:.|...|:..|
Mouse   416 SDLLEKLKWAKEHDAEAKKIAKAGQEFARNNLMGDDIFCYYFKLFQGYANLQVSEPQIREGMKRV 480

  Fly   386 SNKKAVQLY 394
            ..:....|:
Mouse   481 EPQSEDDLF 489

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG31139NP_732797.1 Glyco_transf_90 61..397 CDD:310354 109/355 (31%)
Poglut2NP_076134.1 Filamin 24..130 6/22 (27%)
IG_FLMN 29..129 CDD:214720 5/21 (24%)
Glyco_transf_90 151..484 CDD:310354 108/348 (31%)
Prevents secretion from ER. /evidence=ECO:0000255|PROSITE-ProRule:PRU10138 499..502
Blue background indicates that the domain is not in the aligned region.

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