DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG31139 and Poglut3

DIOPT Version :10

Sequence 1:NP_732797.1 Gene:CG31139 / 42698 FlyBaseID:FBgn0051139 Length:397 Species:Drosophila melanogaster
Sequence 2:NP_997610.1 Gene:Poglut3 / 68304 MGIID:1923765 Length:503 Species:Mus musculus


Alignment Length:384 Identity:105/384 - (27%)
Similarity:170/384 - (44%) Gaps:53/384 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly    30 NEHNPNSNTSYDFVPHILHALAIHR--PCVIGDPK-------CLCHVATIQRDLEPYVDKGITPE 85
            :||..:|       |:||.....|.  .|...||:       |......|::|...:....:...
Mouse   117 SEHVAHS-------PYILKGPVYHEYCDCPEDDPQVWQETLSCPASEPQIEQDFVSFPSINLQQM 174

  Fly    86 MMAQSKRLG------TFYQIIRGRIYRQQ--KCLHPKRCADVEDLLLDMASGVA--DLEFVLNVR 140
            :.....|.|      ..|.|:...|||:.  |....|..:|  ::||.:|..|.  ||||.:|:.
Mouse   175 LKEVPTRFGDERGAVVHYTILNNHIYRRSLGKYTDFKMFSD--EILLSLARKVTLPDLEFYINLG 237

  Fly   141 DWPQVH-FLSGLSGPV----FSYSITNRHLDIMYPAWSFWTTTGPILQHYPHGVGRWDWMRKHLV 200
            |||..| .::...||:    :..|:.:|  ||:.|.:....:|...::...:.:         |.
Mouse   238 DWPLEHRKVNDTPGPIPIISWCGSLDSR--DIILPTYDVTHSTLEAMRGVTNDL---------LS 291

  Fly   201 ARASELP-WSAKRAIGFFRGSRSSPERDSLVRLSQRRPDLVDAQYT------ILATDADPVEKMP 258
            .:.:..| |..|....||||..|..||..||.||:..|.|:||..|      ....:....:.|.
Mouse   292 VQGNTGPSWINKTEKAFFRGRDSREERLQLVLLSKENPQLLDAGITGYFFFQEKEKELGKAKLMG 356

  Fly   259 LVEHCQFKYLFNFRGVAASFRLRHILLCRSLVLHVGDQWQEFFYSQLKPWVHYVPVASDADVDEL 323
            ..:..::||..|..|..|::|..:::|..||||.....:.|.||..||||.||||:  ..::.:|
Mouse   357 FFDFFKYKYQVNVDGTVAAYRYPYLMLGDSLVLKQESPYYEHFYVALKPWKHYVPI--KRNLGDL 419

  Fly   324 AELILYLREHDDLAEEIAERGQQFIWLHLRMEDVQCYWSKMLQEYAKLLTYKVQREPGL 382
            .|.:.:.:|:|:.|::||:.||......|:...:.||:.::||:||:....|.....|:
Mouse   420 LEKVKWAKENDEEAKKIAKEGQLTARDLLQPPRLYCYYYRVLQKYAERQASKPMIRDGM 478

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG31139NP_732797.1 Glyco_transf_90 61..397 CDD:310354 96/351 (27%)
Poglut3NP_997610.1 Filamin. /evidence=ECO:0000255|PROSITE-ProRule:PRU00087 19..129 6/18 (33%)
Filamin 22..126 CDD:395505 4/15 (27%)
Glyco_transf_90 147..481 CDD:329112 95/347 (27%)
Prevents secretion from ER. /evidence=ECO:0000255|PROSITE-ProRule:PRU10138 500..503
Blue background indicates that the domain is not in the aligned region.

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