DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG31139 and Poglut1

DIOPT Version :10

Sequence 1:NP_732797.1 Gene:CG31139 / 42698 FlyBaseID:FBgn0051139 Length:397 Species:Drosophila melanogaster
Sequence 2:NP_001094122.1 Gene:Poglut1 / 288091 RGDID:1306248 Length:392 Species:Rattus norvegicus


Alignment Length:354 Identity:167/354 - (47%)
Similarity:236/354 - (66%) Gaps:15/354 - (4%)


- Green bases have known domain annotations that are detailed below.


  Fly    42 FVPHILHALAIHRPCVIGDPKCLCHVATIQRDLEPYVDKGITPEMMAQ--SKRLGTFYQIIRGRI 104
            |:..|..||..:.||  ....|.|:...|:.||.|: ..||:.:|||:  .:||||.||||:.|:
  Rat    35 FIDQINRALENYEPC--SSQNCSCYHGVIEEDLTPF-RGGISRKMMAEVVRRRLGTHYQIIKHRL 96

  Fly   105 YRQQKCLHPKRCADVEDLLLDMASGVADLEFVLNVRDWPQVHFLSGLSGPVFSYSITNRHLDIMY 169
            :|:..|:.|.||:.||..:|::...:.|:|.|:||||:|||......:.||||:|.|:.:.||||
  Rat    97 FREDDCMFPSRCSGVEHFILEVIRRLPDMEMVINVRDYPQVPKWMEPTIPVFSFSKTSEYHDIMY 161

  Fly   170 PAWSFWTTTGPILQHYPHGVGRWDWMRKHLVARASELPWSAKRAIGFFRGSRSSPERDSLVRLSQ 234
            |||:||.....:...||.|:||||..|:.|:..|::.||..|.:..:|||||:|||||.|:.||:
  Rat   162 PAWTFWEGGPAVWPLYPTGLGRWDLFREDLLRSAAQWPWEKKNSTAYFRGSRTSPERDPLILLSR 226

  Fly   235 RRPDLVDAQYT-------ILATDADPVEK-MPLVEHCQFKYLFNFRGVAASFRLRHILLCRSLVL 291
            :.|.||||:||       :..|...|..| :.|::||::||||||||||||||.:|:.||.|||.
  Rat   227 KNPKLVDAEYTKNQAWKSMKDTLGKPAAKDVHLIDHCKYKYLFNFRGVAASFRFKHLFLCGSLVF 291

  Fly   292 HVGDQWQEFFYSQLKPWVHYVPVASDADVDELAELILYLREHDDLAEEIAERGQQFIWLHLRMED 356
            ||||:|.||||.||||||||:||.:  |:.::.||:.:::.:||||:|||:||.|||..||:|:|
  Rat   292 HVGDEWVEFFYPQLKPWVHYIPVKT--DLSDVQELLQFVKANDDLAQEIAKRGSQFIINHLQMDD 354

  Fly   357 VQCYWSKMLQEYAKLLTYKVQREPGLLEV 385
            :.|||..:|.||:|.|:|.|.|.....::
  Rat   355 ITCYWENLLTEYSKFLSYNVTRRKDYYQI 383

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG31139NP_732797.1 Glyco_transf_90 61..397 CDD:310354 161/335 (48%)
Poglut1NP_001094122.1 Glyco_transf_90 49..388 CDD:310354 162/340 (48%)
Interaction with the consensus sequence C-X-S-X-[PA]-C in peptide substrates. /evidence=ECO:0000250|UniProtKB:Q8NBL1 103..107 1/3 (33%)
Interaction with the consensus sequence C-X-S-X-[PA]-C in peptide substrates. /evidence=ECO:0000250|UniProtKB:Q8NBL1 172..178 0/5 (0%)
Prevents secretion from ER. /evidence=ECO:0000255|PROSITE-ProRule:PRU10138 389..392
Blue background indicates that the domain is not in the aligned region.

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