DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG31139 and Poglut1

DIOPT Version :10

Sequence 1:NP_732797.1 Gene:CG31139 / 42698 FlyBaseID:FBgn0051139 Length:397 Species:Drosophila melanogaster
Sequence 2:NP_759012.1 Gene:Poglut1 / 224143 MGIID:2444232 Length:392 Species:Mus musculus


Alignment Length:370 Identity:166/370 - (44%)
Similarity:241/370 - (65%) Gaps:16/370 - (4%)


- Green bases have known domain annotations that are detailed below.


  Fly    27 CAVNEHNPNSNTSYD-FVPHILHALAIHRPCVIGDPKCLCHVATIQRDLEPYVDKGITPEMMAQ- 89
            |.|.....:|.:.:. |:..|..||..:.||  ....|.|:...|:.||.|: ..||:.:|||: 
Mouse    19 CPVQGRQKDSGSKWKVFLDQINRALENYEPC--SSQNCSCYHGVIEEDLTPF-RGGISRKMMAEV 80

  Fly    90 -SKRLGTFYQIIRGRIYRQQKCLHPKRCADVEDLLLDMASGVADLEFVLNVRDWPQVHFLSGLSG 153
             .::|||.||||:.|::|:..|:.|.||:.||..:|::...:.|:|.|:||||:|||......:.
Mouse    81 VRRKLGTHYQIIKNRLFREDDCMFPSRCSGVEHFILEVIHRLPDMEMVINVRDYPQVPKWMEPTI 145

  Fly   154 PVFSYSITNRHLDIMYPAWSFWTTTGPILQHYPHGVGRWDWMRKHLVARASELPWSAKRAIGFFR 218
            ||||:|.|:.:.|||||||:||.....:...||.|:||||..|:.|:..|::.||..|.:..:||
Mouse   146 PVFSFSKTSEYHDIMYPAWTFWEGGPAVWPLYPTGLGRWDLFREDLLRSAAQWPWEKKNSTAYFR 210

  Fly   219 GSRSSPERDSLVRLSQRRPDLVDAQYT-------ILATDADPVEK-MPLVEHCQFKYLFNFRGVA 275
            |||:|||||.|:.||::.|.||||:||       :..|...|..| :.|::||:::|||||||||
Mouse   211 GSRTSPERDPLILLSRKNPKLVDAEYTKNQAWKSMKDTLGKPAAKDVHLIDHCKYRYLFNFRGVA 275

  Fly   276 ASFRLRHILLCRSLVLHVGDQWQEFFYSQLKPWVHYVPVASDADVDELAELILYLREHDDLAEEI 340
            ||||.:|:.||.|||.||||:|.||||.||||||||:||.:  |:..:.||:.:::.:||:|:||
Mouse   276 ASFRFKHLFLCGSLVFHVGDEWVEFFYPQLKPWVHYIPVKT--DLSNVQELLQFVKANDDIAQEI 338

  Fly   341 AERGQQFIWLHLRMEDVQCYWSKMLQEYAKLLTYKVQREPGLLEV 385
            |:||.|||..||:|:|:.|||..:|.:|:|.|:|.|.|.....::
Mouse   339 AKRGSQFIINHLQMDDITCYWENLLTDYSKFLSYNVTRRKDYYQI 383

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG31139NP_732797.1 Glyco_transf_90 61..397 CDD:310354 157/335 (47%)
Poglut1NP_759012.1 Glyco_transf_90 49..388 CDD:310354 158/340 (46%)
Interaction with the consensus sequence C-X-S-X-[PA]-C in peptide substrates. /evidence=ECO:0000250|UniProtKB:Q8NBL1 103..107 1/3 (33%)
Interaction with the consensus sequence C-X-S-X-[PA]-C in peptide substrates. /evidence=ECO:0000250|UniProtKB:Q8NBL1 172..178 0/5 (0%)
Prevents secretion from ER. /evidence=ECO:0000255|PROSITE-ProRule:PRU10138 389..392
Blue background indicates that the domain is not in the aligned region.

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