DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG31139 and POGLUT3

DIOPT Version :10

Sequence 1:NP_732797.1 Gene:CG31139 / 42698 FlyBaseID:FBgn0051139 Length:397 Species:Drosophila melanogaster
Sequence 2:NP_714916.3 Gene:POGLUT3 / 143888 HGNCID:28496 Length:507 Species:Homo sapiens


Alignment Length:398 Identity:106/398 - (26%)
Similarity:167/398 - (41%) Gaps:82/398 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly    30 NEHNPNSNTSYDFVPHILHALAIHRPCVI-GDPK-------CLCHVATIQRDLEPYVDKGITPEM 86
            :||...|       |:||.....|..|.. .||:       |......|.:|...:....:...:
Human   122 DEHVAQS-------PYILKGPVYHEYCECPEDPQAWQKTLSCPTKEPQIAKDFASFPSINLQQML 179

  Fly    87 MAQSKRLG------TFYQIIRGRIYRQQ--KCLHPKRCADVEDLLLDMASGV--ADLEFVLNVRD 141
            ....||.|      ..|.|:...:||:.  |....|..:|  ::||.:...|  .||||.:|:.|
Human   180 KEVPKRFGDERGAIVHYTILNNHVYRRSLGKYTDFKMFSD--EILLSLTRKVLLPDLEFYVNLGD 242

  Fly   142 WPQVH-FLSGLSGPV----------------FSYSITNRHLDIM----YPAWSFWTTTGPILQHY 185
            ||..| .::|...|:                .:|.||:..|:.|    ....|....|||     
Human   243 WPLEHRKVNGTPSPIPIISWCGSLDSRDVVLPTYDITHSMLEAMRGVTNDLLSIQGNTGP----- 302

  Fly   186 PHGVGRWDWMRKHLVARASELPWSAKRAIGFFRGSRSSPERDSLVRLSQRRPDLVDAQYT----- 245
                   .|:.|            .:||  ||||..|..||..||:||:..|.|:||..|     
Human   303 -------SWINK------------TERA--FFRGRDSREERLQLVQLSKENPQLLDAGITGYFFF 346

  Fly   246 -ILATDADPVEKMPLVEHCQFKYLFNFRGVAASFRLRHILLCRSLVLHVGDQWQEFFYSQLKPWV 309
             ....:....:.|...:..::||..|..|..|::|..:::|..||||.....:.|.||..|:||.
Human   347 QEKEKELGKAKLMGFFDFFKYKYQVNVDGTVAAYRYPYLMLGDSLVLKQDSPYYEHFYMALEPWK 411

  Fly   310 HYVPVASDADVDELAELILYLREHDDLAEEIAERGQQFIWLHLRMEDVQCYWSKMLQEYAKLLTY 374
            ||||:  ..::.:|.|.:.:.:|:|:.|::||:.||......|:...:.||:.::||:||:..:.
Human   412 HYVPI--KRNLSDLLEKVKWAKENDEEAKKIAKEGQLMARDLLQPHRLYCYYYQVLQKYAERQSS 474

  Fly   375 KVQREPGL 382
            |.:...|:
Human   475 KPEVRDGM 482

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG31139NP_732797.1 Glyco_transf_90 61..397 CDD:310354 97/366 (27%)
POGLUT3NP_714916.3 Filamin 24..134 6/18 (33%)
Filamin 27..131 CDD:395505 4/15 (27%)
Glyco_transf_90 151..485 CDD:329112 96/362 (27%)
Prevents secretion from ER. /evidence=ECO:0000255|PROSITE-ProRule:PRU10138 504..507
Blue background indicates that the domain is not in the aligned region.

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