DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG17141 and LSG1

DIOPT Version :9

Sequence 1:NP_651094.2 Gene:CG17141 / 42697 FlyBaseID:FBgn0039020 Length:323 Species:Drosophila melanogaster
Sequence 2:NP_060855.2 Gene:LSG1 / 55341 HGNCID:25652 Length:658 Species:Homo sapiens


Alignment Length:426 Identity:80/426 - (18%)
Similarity:132/426 - (30%) Gaps:175/426 - (41%)


- Green bases have known domain annotations that are detailed below.


  Fly     9 RNAFRLPSKQRINWFPGHMTKGM-RQIQQKLRNVDCIVEIHDARIPLAGRNSQFFDTITGSGV-K 71
            |...||..:|::...|....... ||:.:.:...|.:|:|.|||.||..|.......:..... |
Human   141 RQLVRLEEEQKLILTPFERNLDFWRQLWRVIERSDIVVQIVDARNPLLFRCEDLECYVKEMDANK 205

  Fly    72 PHILVLNKVDLLGAKQQKSVLQQLRRQ-------------------------------------- 98
            .:::::||.|||.|:|:.:......::                                      
Human   206 ENVILINKADLLTAEQRSAWAMYFEKEDVKVIFWSALAGAIPLNGDSEEEANRDDRQSNTTKFGH 270

  Fly    99 ----QPELQH------------------------ILFTNC-----------------------KD 112
                |.|:.|                        ..:.:|                       :|
Human   271 SSFDQAEISHSESEHLPARDSPSLSENPTTDEDDSEYEDCPEEEEDDWQTCSEEDGPKEEDCSQD 335

  Fly   113 QRNNGVLDILPLATRLVSES-SRFNRTQAAEHNLM-----------------------------I 147
            .:.:...|         ||: ||....:...||..                             :
Human   336 WKESSTAD---------SEARSRKTPQKRQIHNFSHLVSKQELLELFKELHTGRKVKDGQLTVGL 391

  Fly   148 IGVPNVGKSSVIN-VLRNVHLKKKSAARVGAEAGITRSVGERIKIQENPPVYMIDTPGILQPSIK 211
            :|.|||||||.|| ::.|   ||.|   |.|..|.|:.. :.:.::  |.:.:.|.||::.||..
Human   392 VGYPNVGKSSTINTIMGN---KKVS---VSATPGHTKHF-QTLYVE--PGLCLCDCPGLVMPSFV 447

  Fly   212 DDEMGMKLALVGCLP-----DHIVGEDLIADYL-------LYWLN---------SHR-------- 247
            ..:..|..:  |.||     ||:....|:...:       .|.:|         .||        
Human   448 STKAEMTCS--GILPIDQMRDHVPPVSLVCQNIPRHVLEATYGINIITPREDEDPHRPPTSEELL 510

  Fly   248 -KYDYVEMLKLSSG-PSDDISA--VLAEYAHREELF 279
             .|.|:.....:.| |....||  :|.:|...:.|:
Human   511 TAYGYMRGFMTAHGQPDQPRSARYILKDYVSGKLLY 546

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG17141NP_651094.2 GTPase_YlqF 20..317 CDD:274669 76/415 (18%)
YlqF 22..206 CDD:206749 54/305 (18%)
LSG1NP_060855.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..31
RbgA 151..554 CDD:224083 76/416 (18%)
HSR1_MMR1 163..444 CDD:206750 53/298 (18%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 250..355 10/113 (9%)
P-loop_NTPase 366..>404 CDD:304359 8/37 (22%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 623..658
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG1161
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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