Protein Alignment CG17141 and GNL2

DIOPT Version :10

• Sequence 1: NP_651094.2
• Gene: CG17141 / 42697
• FlyBaseID: FBgn0039020
• Length: 323
• Species: Drosophila melanogaster
• Sequence 2: NP_001310552.1
• Gene: GNL2 / 29889
• HGNCID: 29925
• Length: 799
• Species: Homo sapiens
• Alignment Length: 347
• Identity: 86/347 - (24%)
• Similarity: 132/347 - (38%)
• Gaps: 123/347 - (35%)

  Fly    33 QIQQKLRNVDCIVEIHDARIPLAGRNSQFFDTITGSGVKP--H-ILVLNKVDLL---GAKQQKSV 91
            ::.:.:.:.|.:|::.|||.|: |..|...:|.. ...||  | |.||||.||:   ..|:..:|
Human   209 ELYKVIDSSDVVVQVLDARDPM-GTRSPHIETYL-KKEKPWKHLIFVLNKCDLVPTWATKRWVAV 271

  Fly    92 LQ----------------------QLRRQQPELQHILFTNCKDQRNNGVLDIL----PLA----- 125
            |.                      ||.||..:..|:.|.....  ..|:|.||    |.:
Human   272 LSQDYPTLAFHASLTNPFGKGAFIQLLRQFGKPWHLTFHALLG--FPGLLCILCPWSPCSFYVLW 334

  Fly   126 ------------------------TRL---VSESSRFNRTQAAEHNLMIIGVPNVGKSSVINVLR 163
                                    |||   :.::|....|...:.::..||.||||||||||.||
Human   335 LERALPKFKLQIPGQTSAPEGSRGTRLPYQILKASCSLHTDKKQISVGFIGYPNVGKSSVINTLR 399

  Fly   164 NVHLKKKSAARVGAEAGITRSVGERIKIQENPPVYMIDTPGILQPSIKDDEMGMKLALVGCLPDH 228
            :     |....|...||.|: |.:.|.:...  :::||.||::.||
Human   400 S-----KKVCNVAPIAGETK-VWQYITLMRR--IFLIDCPGVVYPS------------------- 437

  Fly   229 IVGEDLIADYLLYWLNSHRKYDYVEMLKLSSGPSDDISAVL----AEYAHREELFHKVKQYDGRV 289
               ||...|.:|..:        |::.|:.| |.|.|.|||    .||..:.   :|:..::...
Human   438 ---EDSETDIVLKGV--------VQVEKIKS-PEDHIGAVLERAKPEYISKT---YKIDSWENAE 487

  Fly   290 EVMTNLLAAARKFIHFFRSGQL 311
            :.:..|.         ||:|:|
Human   488 DFLEKLA---------FRTGKL 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17141	NP_651094.2	GTPase_YlqF	20..317	CDD:274669	86/347 (25%)
GNL2	NP_001310552.1	NGP1NT	43..174	CDD:462379
		NGP_1	209..433	CDD:206751	62/235 (26%)
		RbgA	218..524	CDD:440775	86/338 (25%)