DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17141 and Mtg1

DIOPT Version :9

Sequence 1:	NP_651094.2	Gene:	CG17141 / 42697	FlyBaseID:	FBgn0039020	Length:	323	Species:	Drosophila melanogaster
Sequence 2:	NP_955005.2	Gene:	Mtg1 / 212508	MGIID:	2685015	Length:	326	Species:	Mus musculus

Alignment Length:	313	Identity:	141/313 - (45%)
Similarity:	198/313 - (63%)	Gaps:	11/313 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 FRNAFRLPSKQRINWFPGHMTKGMRQIQQKLRNVDCIVEIHDARIPLAGRNSQFFDTITGSGVKP 72
            :|..|.|.......||||||.||::::|..|::|||::|:||||||.:|||..|.:.:   |:||
Mouse    15 WRECFPLQGHDVARWFPGHMAKGLKKMQSSLKSVDCVIEVHDARIPFSGRNPLFQELL---GLKP 76

  Fly    73 HILVLNKVDLLGAKQQKSVLQQLRRQQPELQHILFTNCKDQRNNGVLDILPLATRLVSESSRFNR 137
            |:|||||:||....:|:.::|:|  ::..|.::|||||....|  :..|:|....|:..|.|::|
Mouse    77 HLLVLNKMDLADLTEQQKIVQRL--EEKGLSNVLFTNCVKDEN--IKQIVPKVMELIRCSYRYHR 137

  Fly   138 TQAAEHNLMIIGVPNVGKSSVINVLRNVHLKKKSAARVGAEAGITRSVGERIKIQENPPVYMIDT 202
            .:..|:.:|::|||||||||:||.||..||:...|||||.|.||||:|..||::.|.|.|:::||
Mouse   138 AETPEYCIMVVGVPNVGKSSLINSLRRQHLRTGKAARVGGEPGITRAVTSRIQVCERPLVFLLDT 202

  Fly   203 PGILQPSIKDDEMGMKLALVGCLPDHIVGEDLIADYLLYWLNSHRKYDYVEMLKLSSGPSDDISA 267
            ||:|.|.|:..|.|:||||.|.:.||:|||:.:||||||.||.|..:.||:...|:|. .|.|..
Mouse   203 PGVLAPRIESVETGLKLALCGTVLDHLVGEETMADYLLYTLNRHGLFGYVQHYALASA-CDQIEW 266

  Fly   268 VLAEYAHREELFHKVKQYDGRVEV---MTNLLAAARKFIHFFRSGQLGHMNLD 317
            ||...|.:.....|||...|...|   ..:...|||.|:..||||.||.:.||
Mouse   267 VLKNVAIKLRKTRKVKVLTGTGNVNVIQPDYAMAARDFLRTFRSGLLGQVMLD 319

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17141	NP_651094.2	GTPase_YlqF	20..317	CDD:274669	136/299 (45%)
CG17141	NP_651094.2	YlqF	22..206	CDD:206749	88/183 (48%)
Mtg1	NP_955005.2	GTPase_YlqF	29..319	CDD:274669	136/297 (46%)
Mtg1	NP_955005.2	YlqF	29..206	CDD:206749	88/183 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167834540
Domainoid	1	1.000	123	1.000	Domainoid score	I5597
eggNOG	1	0.900	-	-		E1_COG1161
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H44527
Inparanoid	1	1.050	261	1.000	Inparanoid score	I3092
Isobase	1	0.950	-	0	Normalized mean entropy	S2703
OMA	1	1.010	-	-		QHG58595
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003800
OrthoInspector	1	1.000	-	-		oto94017
orthoMCL	1	0.900	-	-		OOG6_101533
Panther	1	1.100	-	-	LDO	PTHR45782
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R757
SonicParanoid	1	1.000	-	-		X3162
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.740