DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment HP1c and cbx5

DIOPT Version :9

Sequence 1:	NP_651093.1	Gene:	HP1c / 42696	FlyBaseID:	FBgn0039019	Length:	237	Species:	Drosophila melanogaster
Sequence 2:	NP_001073653.1	Gene:	cbx5 / 563396	ZFINID:	ZDB-GENE-030131-5553	Length:	204	Species:	Danio rerio

Alignment Length:	173	Identity:	61/173 - (35%)
Similarity:	93/173 - (53%)	Gaps:	45/173 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 NEPNFVVERIMDKRITSEGKVEYYIKWRGYTSADNTWEPEENCDCPNLIQKF------------- 55
            :|..:|||:::|:|:. :|:|||::||:|:|...||||||:|.|||.||.:|
Zfish    17 DEEEYVVEKVLDRRVV-KGRVEYFLKWKGFTEKHNTWEPEKNLDCPELISEFMKTYKKGNSASPP 80

  Fly    56 -----------------------------EESRAKSKKRGEKKPKCEEIQKLRGYERGLELAEIV 91
                                         ||....|.|  .||.|.:||...||:|||||..:|:
Zfish    81 SSKSSSTGPSSARPKDSSGSSSTSKRKNSEEENGSSSK--PKKKKEDEILVARGFERGLEPEKII 143

  Fly    92 GATDVTGDIKYLVRWQFCDEFDLVPSAQIVEKDPQMLIDYFQK 134
            ||||..||:.:|::|:..||.|||.:.:...|.||::|.::::
Zfish   144 GATDSCGDLMFLMKWKDSDEADLVLAKEANHKCPQIVIAFYEE 186

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
HP1c	NP_651093.1	Chromo	9..58	CDD:278797	27/90 (30%)
HP1c	NP_651093.1	Chromo_shadow	89..134	CDD:279701	18/44 (41%)
cbx5	NP_001073653.1	Chromo	21..69	CDD:306815	26/48 (54%)
cbx5	NP_001073653.1	Chromo_shadow	138..190	CDD:307518	19/49 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	77	1.000	Domainoid score	I8756
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1628171at2759
OrthoFinder	1	1.000	-	-		FOG0000191
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22812
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X422
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	8.020