DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment HP1c and Cbx7

DIOPT Version :9

Sequence 1:	NP_651093.1	Gene:	HP1c / 42696	FlyBaseID:	FBgn0039019	Length:	237	Species:	Drosophila melanogaster
Sequence 2:	XP_006521207.1	Gene:	Cbx7 / 52609	MGIID:	1196439	Length:	251	Species:	Mus musculus

Alignment Length:	233	Identity:	63/233 - (27%)
Similarity:	93/233 - (39%)	Gaps:	64/233 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 EPNFVVERIMDKRITSEGKVEYYIKWRGYTSADNTWEPEENCDCPNLIQKFEESRAKSKKRGEKK 69
            |..|.||.|..||: .:|||||.:||:|:....:||||||:...|.|:..:||...:.:..|.:|
Mouse     8 EQVFAVESIRKKRV-RKGKVEYLVKWKGWPPKYSTWEPEEHILDPRLVMAYEEKEERDRASGYRK 71

  Fly    70 --PKCEEI-------------QKLRGYER-GLELAEIVGATDVTGDIKYLVRWQFCDEFDLVPSA 118
              ||...:             .|.:|.|: ...||..:.:....|.:|..|             |
Mouse    72 RGPKPRRLLLQRLYSMDLRSSHKAKGNEKLCFSLARPLRSGSPMGVVKAGV-------------A 123

  Fly   119 QIVEKDPQMLIDYFQKMAPYSRHIAMRMKGVPEELRLAASRTSY----PHISSAPVEVPPEVDQS 179
            ::|||.|         :.|.......:.:...:.|||  ||..:    ||:.|........:.:|
Mouse   124 ELVEKGP---------LVPTLPFPLRKARKAHKYLRL--SRKKFPPRGPHLESHSHRRELSLQES 177

  Fly   180 AELAGHLGGIAPQV----------DQAPQHHAPMDLAN 207
            |         ||.|          :|||:..|..||.|
Mouse   178 A---------APDVVQTPGDWEPMEQAPEEEAEADLTN 206

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
HP1c	NP_651093.1	Chromo	9..58	CDD:278797	22/48 (46%)
HP1c	NP_651093.1	Chromo_shadow	89..134	CDD:279701	8/44 (18%)
Cbx7	XP_006521207.1	CD_Cbx7	7..62	CDD:349293	25/54 (46%)
Cbx7	XP_006521207.1	CBX7_C	209..240	CDD:375056
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1628171at2759
OrthoFinder	1	1.000	-	-		FOG0000191
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.920