DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment HP1c and Mphosph8

DIOPT Version :9

Sequence 1:	NP_651093.1	Gene:	HP1c / 42696	FlyBaseID:	FBgn0039019	Length:	237	Species:	Drosophila melanogaster
Sequence 2:	NP_001017375.2	Gene:	Mphosph8 / 290270	RGDID:	1305133	Length:	851	Species:	Rattus norvegicus

Alignment Length:	98	Identity:	36/98 - (36%)
Similarity:	54/98 - (55%)	Gaps:	9/98 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 EPNFVVERIMDKRITSEGKVEYYIKWRGYTSADNTWEPEENC-DCPNLIQKFEESRAKSKKRGEK 68
            |..|.||||:|.:... ||..|.::|:||||.|:|||||.:. ||..::.:|.:..|::|.:..:
  Rat    56 EDVFEVERILDMKCEG-GKNLYKVRWKGYTSDDDTWEPEVHLEDCKEVLLEFRKKVAENKAKAVR 119

  Fly    69 KPKCEEIQKLRGYERGLELAEIVGATDVTGDIK 101
            |    :||||   ....::.|.....|..||.|
  Rat   120 K----DIQKL---SLNNDIFEADSDIDQQGDTK 145

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
HP1c	NP_651093.1	Chromo	9..58	CDD:278797	22/49 (45%)
HP1c	NP_651093.1	Chromo_shadow	89..134	CDD:279701	5/13 (38%)
Mphosph8	NP_001017375.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	21..54
		CHROMO	58..109	CDD:214605	23/51 (45%)
		Histone H3K9me3 binding. /evidence=ECO:0000250\|UniProtKB:Q99549	80..87		5/6 (83%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	133..174		5/13 (38%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	240..302
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	315..428
		ANK	586..710	CDD:238125
		ANK 1	591..620
		ANK repeat	594..622	CDD:293786
		Ank_2	597..686	CDD:289560
		ANK repeat	624..655	CDD:293786
		ANK 2	624..653
		ANK repeat	657..686	CDD:293786
		ANK 3	657..686
		ANK 4	690..719
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1911
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1628171at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820