Protein Alignment HP1c and CBX5

DIOPT Version :9

• Sequence 1: NP_651093.1
• Gene: HP1c / 42696
• FlyBaseID: FBgn0039019
• Length: 237
• Species: Drosophila melanogaster
• Sequence 2: NP_001120793.1
• Gene: CBX5 / 23468
• HGNCID: 1555
• Length: 191
• Species: Homo sapiens
• Alignment Length: 157
• Identity: 56/157 - (35%)
• Similarity: 94/157 - (59%)
• Gaps: 26/157 - (16%)

  Fly     3 KNEPNFVVERIMDKRITSEGKVEYYIKWRGYTSADNTWEPEENCDCPNLIQKFEESRAKSKKRGE 67
            ::|..:|||:::|:|:. :|:|||.:||:|::...||||||:|.|||.||.:|.:...|.|:...
Human    15 EDEEEYVVEKVLDRRVV-KGQVEYLLKWKGFSEEHNTWEPEKNLDCPELISEFMKKYKKMKEGEN 78

  Fly    68 KKPK---------------CEEIQK----------LRGYERGLELAEIVGATDVTGDIKYLVRWQ 107
            .||:               .::|:.          .||:|||||..:|:||||..||:.:|::|:
Human    79 NKPREKSESNKRKSNFSNSADDIKSKKKREQSNDIARGFERGLEPEKIIGATDSCGDLMFLMKWK 143

  Fly   108 FCDEFDLVPSAQIVEKDPQMLIDYFQK 134
            ..||.|||.:.:...|.||::|.::::
Human   144 DTDEADLVLAKEANVKCPQIVIAFYEE 170

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HP1c	NP_651093.1	Chromo	9..58	CDD:278797	25/48 (52%)
		Chromo_shadow	89..134	CDD:279701	18/44 (41%)
CBX5	NP_001120793.1	CD_HP1alpha_Cbx5	19..68	CDD:349298	25/49 (51%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	70..117		6/46 (13%)
		CSD_HP1alpha_Cbx5	116..173	CDD:349302	24/55 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1911
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1628171at2759
OrthoFinder	1	1.000	-	-		FOG0000191
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22812
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X422
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	8	7.880