DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment HP1c and cec-4

DIOPT Version :9

Sequence 1:	NP_651093.1	Gene:	HP1c / 42696	FlyBaseID:	FBgn0039019	Length:	237	Species:	Drosophila melanogaster
Sequence 2:	NP_501231.1	Gene:	cec-4 / 177536	WormBaseID:	WBGene00017990	Length:	270	Species:	Caenorhabditis elegans

Alignment Length:	203	Identity:	38/203 - (18%)
Similarity:	86/203 - (42%)	Gaps:	44/203 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 KNEPNFVVERIMDKRITSEGKVEYYIK---WRGYTSADNTWEPEENCDCPNLIQKFEESRAKSKK 64
            ||..:|  ::|:..::..|..|||.::   .:..|:.:..::.::     :|:..:::   |..|
Worm    24 KNHDDF--KKIIGHKVVEEHYVEYEVELTSGKTITATEFDFKGDD-----SLLSTYKK---KVTK 78

  Fly    65 RGEKKPKCEEIQKLRGYERGLELAEIVGATDVTGDIKYLVRWQFCDEFDLVPSAQIVEKDPQMLI 129
            :.:.......::::..:.:            |.|...|||:|:....  .|.::::.|:|.....
Worm    79 QSDDSSGEYAVERVLAHRK------------VKGSPLYLVQWKGYPH--PVWNSEMWEEDLDNCK 129

  Fly   130 DYFQKMAPYSRHIAMRMKGVPEELRLAASRTSYPHISSAPVEVPPEVDQSA----ELAGHLGGIA 190
            |.   :|.|.:|        .|:|::|.:....|  |..|.:.|..:.:.|    :.....|.||
Worm   130 DL---LAAYKKH--------QEDLKIAQTPKKTP--SKTPKKTPKSLKRRALTPSDDEEEAGPIA 181

  Fly   191 PQVDQAPQ 198
            |:..:.|:
Worm   182 PEPKKTPK 189

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
HP1c	NP_651093.1	Chromo	9..58	CDD:278797	7/51 (14%)
HP1c	NP_651093.1	Chromo_shadow	89..134	CDD:279701	10/44 (23%)
cec-4	NP_501231.1	CHROMO	86..140	CDD:214605	13/78 (17%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1911
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1628171at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820