Protein Alignment HP1c and Cbx3

DIOPT Version :10

• Sequence 1: NP_651093.1
• Gene: HP1c / 42696
• FlyBaseID: FBgn0039019
• Length: 237
• Species: Drosophila melanogaster
• Sequence 2: NP_031650.3
• Gene: Cbx3 / 12417
• MGIID: 108515
• Length: 183
• Species: Mus musculus
• Alignment Length: 146
• Identity: 63/146 - (43%)
• Similarity: 95/146 - (65%)
• Gaps: 17/146 - (11%)

  Fly     5 EP-NFVVERIMDKRITSEGKVEYYIKWRGYTSADNTWEPEENCDCPNLIQKFEES-RAKSKKRGE 67
            || .||||:::|:|:.: |||||::||:|:|.||||||||||.|||.||:.|..| :|..:|.|.
Mouse    26 EPEEFVVEKVLDRRVVN-GKVEYFLKWKGFTDADNTWEPEENLDCPELIEAFLNSQKAGKEKDGT 89

  Fly    68 K--------------KPKCEEIQKLRGYERGLELAEIVGATDVTGDIKYLVRWQFCDEFDLVPSA 118
            |              |.|.:...|.||:.|||:...|:||||.:|::.:|::|:..||.|||.:.
Mouse    90 KRKSLSDSESDDSKSKKKRDAADKPRGFARGLDPERIIGATDSSGELMFLMKWKDSDEADLVLAK 154

  Fly   119 QIVEKDPQMLIDYFQK 134
            :...|.||::|.::::
Mouse   155 EANMKCPQIVIAFYEE 170

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HP1c	NP_651093.1	CD_CSD	8..55	CDD:475127	30/46 (65%)
		CSD	85..135	CDD:349275	18/50 (36%)
Cbx3	NP_031650.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..28		1/1 (100%)
		CD_HP1gamma_Cbx3	29..78	CDD:349299	31/49 (63%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	78..125		13/46 (28%)
		CSD_HP1gamma_Cbx3	116..173	CDD:349303	21/55 (38%)