Protein Alignment HP1c and CBX3

DIOPT Version :9

• Sequence 1: NP_651093.1
• Gene: HP1c / 42696
• FlyBaseID: FBgn0039019
• Length: 237
• Species: Drosophila melanogaster
• Sequence 2: NP_009207.2
• Gene: CBX3 / 11335
• HGNCID: 1553
• Length: 183
• Species: Homo sapiens
• Alignment Length: 146
• Identity: 63/146 - (43%)
• Similarity: 95/146 - (65%)
• Gaps: 17/146 - (11%)

  Fly     5 EP-NFVVERIMDKRITSEGKVEYYIKWRGYTSADNTWEPEENCDCPNLIQKFEES-RAKSKKRGE 67
            || .||||:::|:|:.: |||||::||:|:|.||||||||||.|||.||:.|..| :|..:|.|.
Human    26 EPEEFVVEKVLDRRVVN-GKVEYFLKWKGFTDADNTWEPEENLDCPELIEAFLNSQKAGKEKDGT 89

  Fly    68 K--------------KPKCEEIQKLRGYERGLELAEIVGATDVTGDIKYLVRWQFCDEFDLVPSA 118
            |              |.|.:...|.||:.|||:...|:||||.:|::.:|::|:..||.|||.:.
Human    90 KRKSLSDSESDDSKSKKKRDAADKPRGFARGLDPERIIGATDSSGELMFLMKWKDSDEADLVLAK 154

  Fly   119 QIVEKDPQMLIDYFQK 134
            :...|.||::|.::::
Human   155 EANMKCPQIVIAFYEE 170

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HP1c	NP_651093.1	Chromo	9..58	CDD:278797	30/48 (63%)
		Chromo_shadow	89..134	CDD:279701	17/44 (39%)
CBX3	NP_009207.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..28		1/1 (100%)
		CD_HP1gamma_Cbx3	29..78	CDD:349299	31/49 (63%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	79..125		13/45 (29%)
		CSD_HP1gamma_Cbx3	116..173	CDD:349303	21/55 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165142985
Domainoid	1	1.000	78	1.000	Domainoid score	I8841
eggNOG	1	0.900	-	-		E1_KOG1911
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1628171at2759
OrthoFinder	1	1.000	-	-		FOG0000191
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X422
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	9	8.710