DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment vret and Tdrd1

DIOPT Version :10

Sequence 1:NP_651092.1 Gene:vret / 42695 FlyBaseID:FBgn0263143 Length:691 Species:Drosophila melanogaster
Sequence 2:XP_006527536.1 Gene:Tdrd1 / 83561 MGIID:1933218 Length:1173 Species:Mus musculus


Alignment Length:531 Identity:97/531 - (18%)
Similarity:189/531 - (35%) Gaps:160/531 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly   237 RTIPLSTVAVTEEDKTKSLLEDGVS-----------------KCVVCQNWTDTFCKLCKMP-FCN 283
            :|.|.|.|...:..|:..|.|:.:|                 .|..|..:....|..||.. :|:
Mouse   120 KTKPSSNVTPEKSKKSHKLFENALSVNNPALFNSLGPPLRSTTCHRCGLFGSLRCSQCKQTYYCS 184

  Fly   284 ASCFADVAEQHKQACGKGEILNLDEKVGRKYP-----------KPGLPPSGSKVRITAFEQTNVV 337
            .:|.......|...|...: .:|::....|.|           :...||..:|......|:....
Mouse   185 TACQRRDWSSHSTICRPVQ-QSLNKLEDNKSPFETKAIEVKSEQVDCPPGVTKEITAGAERVMFS 248

  Fly   338 YVRSADIQIDIAYYTVLTE--------VMMLGKD--------ASKLQST-----------PVCGQ 375
            .:||..::..:.....:||        :.:...:        ::.|:.|           ||.|:
Mouse   249 DLRSLQLKKTMEIKGTVTEFKHPSNFYIQLYSSEVLENMNQLSTSLKETYANVVPEDGYLPVKGE 313

  Fly   376 IVLYKF--EGHMSRAMVLNVDNI-KEIYVVFIDFGSVEVTQLERLYECSSYLAGLTCY-PVAVK- 435
            :.:.|:  :...:||:|..||.: ::.:|::||:|:.|:..::.::..|   .||..: |.|:| 
Mouse   314 VCVAKYTVDQTWNRAIVQAVDVLQRKAHVLYIDYGNEEMIPIDSVHPLS---RGLDLFPPSAIKC 375

  Fly   436 -LRGV-P------------------RRFVGPNIREVMYE-----------------LDQSLV--- 460
             :.|| |                  .:|....:.:::.|                 ||..||   
Mouse   376 CVSGVIPTAGEWSEGCVAAVKALLFEQFCSVKVMDILEEEVLTCAVDLVLQSSGKQLDHVLVEMG 440

  Fly   461 FNIK---YSSREYDTSKGM-----QVVVMTEIDINRSLNRLFKTILTPVEPSVSDLGYKEDCLPY 517
            :.:|   .||.|.......     :|.|.::|..:|  |.|...:||                  
Mouse   441 YGVKPGEQSSTEQSVDHSALEDVGRVTVESKIVTDR--NALIPKVLT------------------ 485

  Fly   518 IPLHCGKNINVVVMDNTFIQCGFI---------YCTSIDLAYEVTKMQRDIQEYGEKIAKCATYA 573
              |:.|...           ||.:         :|..:...:::.::|..:.||...:...:.:.
Mouse   486 --LNVGDEF-----------CGVVAHIQTPEDFFCQQLQSGHKLAELQESLSEYCGHVIPRSDFY 537

  Fly   574 PPINELCIAKY--EGKWRRGLSVELVGDGYPSILFIDYGNIVPTHVTDIRPYPPQFI-FPIMTTQ 635
            |.|.::|.|::  :.:|.|...:....:....:.::||||.....:..:.|..|:.: .|:....
Mouse   538 PTIGDVCCAQFSEDDQWYRASVLAYASEESVLVGYVDYGNFEILSLKRLCPIIPKLLDLPMQALN 602

  Fly   636 LDLIGVPEKPT 646
            ..|.||  ||:
Mouse   603 CVLAGV--KPS 611

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
vretNP_651092.1 TUDOR 322..438 CDD:425754 28/148 (19%)
Tudor_vreteno-like_rpt1 371..424 CDD:410515 15/55 (27%)
TUDOR 524..640 CDD:425754 20/127 (16%)
Tudor_vreteno-like_rpt2 576..631 CDD:410516 11/57 (19%)
Tdrd1XP_006527536.1 zf-MYND 163..199 CDD:460312 8/35 (23%)
Tudor_TDRD1_rpt1 263..392 CDD:410479 27/131 (21%)
Tudor_TDRD1_rpt2 513..594 CDD:410480 15/80 (19%)
TUDOR 716..825 CDD:425754
Tudor_SF 937..1052 CDD:470623
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.