Protein Alignment vret and tdrd6a

DIOPT Version :10

• Sequence 1: NP_651092.1
• Gene: vret / 42695
• FlyBaseID: FBgn0263143
• Length: 691
• Species: Drosophila melanogaster
• Sequence 2: NP_001410719.2
• Gene: tdrd6a / 565665
• ZFINID: ZDB-GENE-041001-210
• Length: 2117
• Species: Danio rerio
• Alignment Length: 717
• Identity: 145/717 - (20%)
• Similarity: 236/717 - (32%)
• Gaps: 225/717 - (31%)

  Fly    29 TNESGQKLIMEAPLPPKDEKEQRATRQA-KYPYL---------VVPKSSPYVTEKMLINFFGRAL 83
            |..|..|.|......|.:..||:..:|| .:|.|         :...:||:       ..|.:..
Zfish   206 TGTSDLKRISSIRTKPVEIIEQKEKQQAYMFPELQTDTVETVVITEVTSPF-------RIFCQLK 263

  Fly    84 IKEMEFRRLS---------RV--YFVYFENIAS-----------LETAQQRVQRYPNLIKCITGR 126
            :...|.::|:         ||  ||...||:.|           ..:..|:|....|:::.:...
Zfish   264 VFSQELKKLTEQITQYYEGRVGSYFARAENLGSPCASRGSDGKWYRSVLQQVMSANNVVEVLHVD 328

  Fly   127 PQKEREITSDPVTSTEPMPTPGPAISATERTPVNHNREVPISTGGQNHPEFFRPPLVT------- 184
            ..|::.:   .|.:.:|:.:                             ||||.|:||
Zfish   329 YGKKQFV---QVENVKPLAS-----------------------------EFFRMPVVTYVCSLHG 361

  Fly   185 -----------KDDYKRGSLLATNDPIQRYLNVKYEFALERHDIYKLKDETRIPQVVLHFRSGRT 238
                       :.||.:..||      .|.:..|:::......::         .|.|:
Zfish   362 IVDKGVGWTASQIDYLKSLLL------NRTVIAKFQYQSLSEGVH---------YVTLY------ 405

  Fly   239 IPLSTVAVTEEDKTKSLLEDGVSKCVVCQNWTDTFCKLCKMPFCNASCFADVAEQHKQACGKGEI 303
                    .||:...:.|.:...||.:..:.|                .||.|.|...:..|.:|
Zfish   406 --------GEENTNINKLFELKPKCSLDSDMT----------------LADFAVQKSPSSQKSKI 446

  Fly   304 LNLDEK--VGRKYPKPGLPPSGSKVRITAF-------EQTNVVYVRSAD----IQIDIAYYTVLT 355
            ....|.  :...|       |..||....|       ..|::..|:..|    ..|....|....
Zfish   447 SRTTESTHINETY-------SDLKVNKPVFFTETLTPNSTHMAVVQHVDSPGKFWIQTQRYADEF 504

  Fly   356 EVMMLG-----KDASKLQS---TPVCGQIVLYKF-EGHMSRAMVLNV-DNIKEIYVVFIDFGSVE 410
            :::|.|     .|.:..:|   .||.|.|...|. :|...||.|..| |...|:|  |:|:|:.|
Zfish   505 DLLMNGLGNLYSDPTSTESLIRKPVVGLICAAKAQDGVFYRAAVYKVIDKTAEVY--FLDYGNTE 567

  Fly   411 VTQLERLYECSSYLAGLTCYPVAVKLRGVPRR----------FVGPNIREVMYEL-------DQS 458
            |.....|.:.......|....|...|.||..|          |....:|:.:.:|       |..
Zfish   568 VVDSFNLRQLPLRFQQLPAVAVKCSLHGVKPRLKLWEERATLFFSKLVRDRIIDLHVQDKQQDTH 632

  Fly   459 LVFNIKYS-SREYDTSK-----GMQVVVMTEIDINRSLNRLFKT------ILTPVEPSV------ 505
            :|..:..| ..|.|.||     |..|...:.:|.:.:.:...||      .||..:|..
Zfish   633 IVQLVDPSLDGEKDVSKLLCNAGFAVSEKSIVDYSATRSCGLKTTHASGVFLTGTQPQTPCSSSV 697

  Fly   506 ---SDLGYKEDCLPYIPLHCGKNINVVVM----DNTFIQCGFIYCTSIDLAYEVTKMQRDIQEYG 563
               |...:||...|     .|.::.|.|.    .|.|      :|.....|..:..:.:|||.:.
Zfish   698 VMDSASAFKEYLFP-----IGSSLEVTVSYIENPNDF------WCQKARNAACLEVLMQDIQRFY 751

  Fly   564 EKIAKCATYAPPINELCIAKY--EGKWRRGLSVELVGDGYPSILFIDYGNIVPTHVTDIRPYPPQ 626
            ..    :.:.|.:...|:|::  .|.|.|.|.::.....:..:||||||......:.|:|...|.
Zfish   752 SH----SEFEPLLEAACVARHPETGIWYRALVIQKHQTPHVDVLFIDYGQTKKVAIEDLRKITPA 812

  Fly   627 FI 628
            |:
Zfish   813 FL 814

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vret	NP_651092.1	TUDOR	322..438	CDD:425754	35/136 (26%)
		Tudor_vreteno-like_rpt1	371..424	CDD:410515	19/54 (35%)
		TUDOR	524..640	CDD:425754	26/111 (23%)
		Tudor_vreteno-like_rpt2	576..631	CDD:410516	16/55 (29%)
tdrd6a	NP_001410719.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1125..1216