DRSC/TRiP Functional Genomics Resources

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Protein Alignment vret and Tdrd1

DIOPT Version :10

Sequence 1:NP_651092.1 Gene:vret / 42695 FlyBaseID:FBgn0263143 Length:691 Species:Drosophila melanogaster
Sequence 2:XP_038959137.1 Gene:Tdrd1 / 292129 RGDID:1306140 Length:1174 Species:Rattus norvegicus


Alignment Length:639 Identity:116/639 - (18%)
Similarity:227/639 - (35%) Gaps:170/639 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly   140 STEPMPTPGPAISATERTPVNHNREVPISTGGQNHPEF-FRPPLVTKDDYKRGSLLATNDPIQRY 203
            ||..|..|........:.|.:.:...|:..  .|||.| .:.|   ::..|:.:.|....     
  Rat    10 STCKMAEPFNFEKKESKLPPHDSLRSPVPQ--HNHPNFRLKSP---ENGNKKNNFLLCEQ----- 64

  Fly   204 LNVKYEFALERHDIYKLK-------------DETRIPQVVLHFRSGRTIPLS------------- 242
             |.:|..:.|.:.:....             |...:|       :|..:.||             
  Rat    65 -NKQYLASQEDNSVVSSNPAGINGEVGGSKGDRKTLP-------TGNPVSLSLGNNSPPNQVKTK 121

  Fly   243 -TVAVTEEDKTKS--LLEDGVS-----------------KCVVCQNWTDTFCKLCKMP-FCNASC 286
             :.|||.|...||  |.|:.:|                 .|..|..:....|..||.. :|:.:|
  Rat   122 PSNAVTPEKSKKSHKLFENALSVNNPALFNSLGPPLRSTTCHRCGLFGSLRCSQCKQTYYCSTAC 186

  Fly   287 FADVAEQHKQACG--KGEILNLDEK--------VGRKYPKPGLPPSGSKVRITAFEQTNVVYVRS 341
            .......|...|.  :..:..|::.        :..|..:...|...:|......|:.....:||
  Rat   187 QRRDWSSHSTICRPVQQSLHKLEDNKSPFETKTIDVKNEQVACPLGVTKEMTAGAERVMFSDLRS 251

  Fly   342 ADIQIDIAYYTVLTE--------VMMLGKD--------ASKLQST-----------PVCGQIVLY 379
            ..::..:.....:||        |.:...:        ::.|:.|           ||.|::.:.
  Rat   252 LQLRKSMEIKGTVTEFKHPGHFYVQLYSSEVLEYMNQLSASLKETYANMVPEDGYLPVKGEVCVA 316

  Fly   380 KF--EGHMSRAMVLNVDNI-KEIYVVFIDFGSVEVTQLERLYECSSYL-----AGLTCYPVAVKL 436
            |:  :...:||:|..||.: |:.:|::||:|:.|:..::|:::.|..:     :.:.||...|  
  Rat   317 KYTVDQTWNRAVVEGVDVLQKKAHVLYIDYGNEEIIPVDRIHQLSRSISLFPPSAIKCYVSGV-- 379

  Fly   437 RGVPRRFVGPNIREVMYELDQSLVFNIKYSSREYDTSKGMQVVVMTEIDINRSLNRLFKTI---- 497
              ||.  .|....:.:..: ::|:|....|.:..|.|:...:....::.:..|..:|...:    
  Rat   380 --VPA--AGEWTEDCVVAV-KALLFEQYCSIKVVDISEEEGLTCAVDVVLQSSGKQLDHVLVEMG 439

  Fly   498 --LTPVEPSVS----DLGYKED----------------CLP-YIPLHCGKNINVVVMDNTFIQCG 539
              :.|.|||..    |.|..||                .:| .:.|:.|...           ||
  Rat   440 YGVKPDEPSSKKQSMDPGTSEDTGRLTAENRIGAERNALVPTVLTLNVGDEF-----------CG 493

  Fly   540 FI---------YCTSIDLAYEVTKMQRDIQEYGEKIAKCATYAPPINELCIAKY--EGKWRRGLS 593
            .:         :|..:...:::.::|..:.||...:...:.:.|.|.::|.|::  :.:|.|...
  Rat   494 VVAHIQTPEDFFCQQLQSGHKLAELQESLSEYCSHVTPRSDFYPTIGDMCCAQFSEDDQWYRASV 558

  Fly   594 VELVGDGYPSILFIDYGNIVPTHVTDIRPYPPQFI-FPIMTTQLDLIGVPEKPT 646
            :....:....:.::||||.....:..:.|..|:.: .|:......|.||  ||:
  Rat   559 LAYASEESVLVGYVDYGNFEILSLKRLCPIIPKLLDLPMQALNCVLAGV--KPS 610

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
vretNP_651092.1 TUDOR 322..438 CDD:425754 29/150 (19%)
Tudor_vreteno-like_rpt1 371..424 CDD:410515 17/55 (31%)
TUDOR 524..640 CDD:425754 20/127 (16%)
Tudor_vreteno-like_rpt2 576..631 CDD:410516 11/57 (19%)
Tdrd1XP_038959137.1 zf-MYND 162..198 CDD:460312 8/35 (23%)
Tudor_TDRD1_rpt1 262..391 CDD:410479 28/134 (21%)
Tudor_TDRD1_rpt2 512..593 CDD:410480 15/80 (19%)
TUDOR 709..825 CDD:425754
Tudor_SF 938..1053 CDD:470623
Blue background indicates that the domain is not in the aligned region.

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